Development Level

Tbio 6 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
decreased grip strength 1 | 116
increased blood uric acid leve... 1 | 5
increased circulating chloride... 1 | 41
increased granulocyte number 1 | 1
polycystic kidney 1 | 15

Disease

Carcinoma 8 | 11,493
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Cancer 7 | 2,499
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
ovarian cancer 7 | 8,520
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung cancer 6 | 4,740
pancreatic cancer 6 | 2,398
psoriasis 6 | 6,694
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
lung carcinoma 5 | 2,843
osteosarcoma 5 | 7,950
subependymal giant cell astrocytoma 5 | 2,287
Alzheimer's disease 4 | 658
Liver Cirrhosis, Experimental 4 | 769
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
group 3 medulloblastoma 4 | 4,104
invasive ductal carcinoma 4 | 2,951
medulloblastoma, large-cell 4 | 6,241
primary pancreatic ductal adenocarcinoma 4 | 1,109
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Kidney cancer 3 | 2,613
Mammary Neoplasms 3 | 425
Myocardial Reperfusion Injury 3 | 37
Neurodegenerative Diseases 3 | 38
Neurodegenerative Disorders 3 | 79
Parkinson's disease 3 | 392
Reperfusion Injury 3 | 86
Toxic encephalopathy 3 | 141
fibroadenoma 3 | 559
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
ulcerative colitis 3 | 1,819
Acute coronary syndrome 2 | 39
Adult onset 2 | 82
Alzheimer Disease 2 | 83
Amyotrophic lateral sclerosis 2 | 451
Autosomal recessive predisposition 2 | 1,442
Brain disease 2 | 96
COPD 2 | 118
Cerebral Hemorrhage 2 | 42
Cerebrovascular disease 2 | 238
Chemical and Drug Induced Liver Injury 2 | 195
Deglutition Disorders 2 | 132
Dementia 2 | 175
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Disease Models, Animal 2 | 155
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Edema 2 | 81
Failure to gain weight 2 | 365
Heart disease 2 | 306
Huntington's disease 2 | 76
Hypersensitivity reaction type II disease 2 | 253
Kidney disease 2 | 430
Myopathy 2 | 185
Neurodegenerative disease 2 | 414
Neuropathy 2 | 261
Osteoporosis 2 | 363
Pediatric failure to thrive 2 | 365
Schizophrenia 2 | 1,160
Short stature 2 | 531
Spermatic cord torsion 2 | 12
Splenomegaly 2 | 190
Status Epilepticus 2 | 98
Weight Gain 2 | 100
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
primitive neuroectodermal tumor 2 | 3,035
Abnormal brain FDG positron emission tomography 1 | 9
Chronic diarrhea 1 | 29
Colitis, Ulcerative 1 | 59
Copper-Overload Cirrhosis 1 | 11
Degenerative disc disease 1 | 35
Difficulty making arithmetical calculations 1 | 8
EEG with continuous slow activity 1 | 7
Learning Disorders 1 | 29
Mycoplasma Infections 1 | 3
Neurotoxicity Syndromes 1 | 26
Pemphigus 1 | 23
Peptic Ulcer 1 | 27
Repeated speech 1 | 9
Restrictive behavior 1 | 7
Ureterocele 1 | 14
Zollinger-Ellison syndrome 1 | 18

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 4 | 4,145

Reactome Pathway

Caspase-mediated cleavage of c... 11 | 11
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth arrest-specific protein 2 GAS2 Tbio Non-IDG -1.70451 49.0 218
Spectrin alpha chain, non-erythrocytic 1 SPTAN1 Tbio Non-IDG -2.42514 269.0 268
Caspase-6 CASP6 Tchem Enzyme -2.49135 293.6 874
Caspase-7 CASP7 Tchem Enzyme -2.69052 418.1 800
Gelsolin GSN Tbio Non-IDG -3.11676 1340.4 481
Plectin PLEC Tbio Non-IDG -2.50749 337.2 130
Caspase-8 CASP8 Tchem Enzyme -3.54224 3121.4 1045
Caspase-3 CASP3 Tchem Enzyme -4.32112 18132.3 1689
Drebrin-like protein DBNL Tbio Non-IDG -1.16567 21.1 172
Microtubule-associated protein tau MAPT Tchem Non-IDG -3.88207 7239.3 3951