Development Level

Tbio 11 | 11,651
Tchem 2 | 1,388

IMPC Phenotype

abnormal coat appearance 1 | 31
decreased circulating glucose ... 1 | 126
increased lean body mass 1 | 172
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 12 | 11,493
glioblastoma 8 | 5,792
ovarian cancer 8 | 8,520
Astrocytoma, Pilocytic 6 | 3,081
ependymoma 6 | 4,679
lung cancer 6 | 4,740
Mucopolysaccharidosis 5 | 26
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
diabetes mellitus 5 | 1,728
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
oligodendroglioma 5 | 2,850
osteosarcoma 5 | 7,950
psoriasis 5 | 6,694
Breast cancer 4 | 3,578
Duchenne muscular dystrophy 4 | 601
Pick disease 4 | 1,894
colon cancer 4 | 1,478
group 3 medulloblastoma 4 | 4,104
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
Atherosclerosis 3 | 291
Autosomal recessive predisposition 3 | 1,442
Big calvaria 3 | 147
Cancer 3 | 2,499
Coarse facial features 3 | 108
Hyperkyphosis 3 | 111
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Kyphosis deformity of spine 3 | 114
Macroglossia 3 | 65
Multiple myeloma 3 | 1,332
Short stature 3 | 531
Thickened facial skin with coarse facial features 3 | 108
aldosterone-producing adenoma 3 | 665
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
limb girdle muscular dystrophy 2A 3 | 213
pancreatic cancer 3 | 2,398
ulcerative colitis 3 | 1,819
Blind Vision 2 | 111
Blindness, Legal 2 | 110
Concave bridge of nose 2 | 195
Congenital deafness 2 | 185
Congenital pes cavus 2 | 88
Contracture 2 | 96
Contracture of joint 2 | 93
Deafness 2 | 198
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Down syndrome 2 | 499
Ehlers-Danlos syndrome 2 | 43
Epilepsy 2 | 792
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Gangliosidosis 2 | 20
Glaucoma 2 | 239
Hearing Loss, Partial 2 | 185
Hepatomegaly 2 | 285
Hernia, Inguinal 2 | 89
Long narrow head 2 | 75
Melanoma 2 | 711
Myopia 2 | 176
Narrow cranium shape 2 | 75
Narrow head shape 2 | 75
Narrow skull shape 2 | 75
Nerve Degeneration 2 | 121
Neuro-degenerative disease 2 | 43
Neurodegenerative Disorders 2 | 79
Neurodegenerative disease 2 | 414
Osteoarthritis 2 | 184
Pfaundler-Hurler Syndrome 2 | 12
Schizophrenia 2 | 1,160
Seizures 2 | 596
Turridolichocephaly 2 | 75
Umbilical hernia 2 | 93
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
gastric carcinoma 2 | 807
hearing impairment 2 | 199
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pterygium 2 | 76
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074
tuberculosis 2 | 2,010

Tissue

Endocrine System 13 | 18,159
Nervous System 13 | 16,725
Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 6 | 4,145

Reactome Pathway

CS/DS degradation 13 | 13
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hyaluronidase-1 HYAL1 Tbio Enzyme -1.88328 77.3 220
Hyaluronidase-3 HYAL3 Tbio Enzyme -0.92743 7.88 126
Neurocan core protein NCAN Tbio Non-IDG -2.19768 158.4 127
Iduronate 2-sulfatase IDS Tbio Enzyme -1.85004 64.1 138
Beta-hexosaminidase subunit beta HEXB Tchem Enzyme -2.18934 146.3 132
Decorin DCN Tbio Non-IDG -3.05208 1155.4 480
Versican core protein VCAN Tbio Non-IDG -2.88501 795.4 190
Alpha-L-iduronidase IDUA Tbio Enzyme -2.45679 291.5 129
Chondroitin sulfate proteoglycan 4 CSPG4 Tbio Non-IDG -2.20166 186.1 395
Chondroitin sulfate proteoglycan 5 CSPG5 Tbio Non-IDG -2.55925 360.8 181