Development Level

Tchem 5 | 1,598
Tclin 5 | 613
Tbio 3 | 11,445

IMPC Phenotype

decreased body weight 3 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased total body fat amoun... 2 | 207
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal head morphology 1 | 10
decreased bone mineral content 1 | 151
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased heart weight 1 | 27
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating fructosa... 1 | 13
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
tremors 1 | 39

Disease

atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 11 | 4,679
glioblastoma 11 | 5,792
group 3 medulloblastoma 11 | 4,104
medulloblastoma, large-cell 11 | 6,241
Astrocytoma, Pilocytic 10 | 3,081
Carcinoma 10 | 11,493
adult high grade glioma 10 | 3,801
primitive neuroectodermal tumor 10 | 3,035
Schizophrenia 9 | 1,160
osteosarcoma 9 | 7,950
oligodendroglioma 8 | 2,850
Bipolar Disorder 7 | 666
Pick disease 7 | 1,894
Toxic encephalopathy 7 | 141
astrocytic glioma 7 | 2,597
Epilepsy 6 | 792
Parkinson's disease 6 | 392
ovarian cancer 6 | 8,520
Alcoholic Intoxication, Chronic 5 | 289
Alcoholism 5 | 45
Arteriosclerotic Parkinsonism 5 | 8
Depressive disorder 5 | 409
Extrapyramidal disease 5 | 8
General anesthesia 5 | 53
Influenza A Prevention 5 | 7
Influenza due to Influenza A virus 5 | 7
Local anesthesia 5 | 40
Major Depressive Disorder 5 | 301
Mental Depression 5 | 333
Parkinsonism 5 | 18
Postencephalitic parkinsonism 5 | 12
psoriasis 5 | 6,694
subependymal giant cell astrocytoma 5 | 2,287
Alzheimer's disease 4 | 658
Cerebrovascular disease 4 | 238
Cocaine-Related Disorders 4 | 92
Huntington's disease 4 | 76
Intellectual disability 4 | 1,016
Unipolar Depression 4 | 250
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
Alcohol dependence 3 | 107
Amyotrophic lateral sclerosis 3 | 451
Autistic Disorder 3 | 364
Breast cancer 3 | 3,578
Dementia 3 | 175
Highly variable severity 3 | 157
Hyperalgesia 3 | 83
Kidney cancer 3 | 2,613
Moderate to Severe Alzheimer's Type Dementia 3 | 5
Mood Disorders 3 | 184
Opiate dependence 3 | 29
Variable expressivity 3 | 157
juvenile dermatomyositis 3 | 1,187
lung cancer 3 | 4,740
non primary Sjogren syndrome sicca 3 | 891
primary Sjogren syndrome 3 | 735
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Autism Spectrum Disorders 2 | 75
Autism spectrum disorder 2 | 101
Brain Ischemia 2 | 110
Dull intelligence 2 | 645
Encephalitis 2 | 64
Fetal alcohol syndrome 2 | 22
High pressure neurological syndrome 2 | 9
Large intestine cancer 2 | 126
Lennox-Gastaut syndrome 2 | 34
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Morphine dependence 2 | 16
Neurodevelopmental Disorders 2 | 70
Polycystic ovary syndrome 2 | 360
Poor school performance 2 | 645
Seizures 2 | 596
Simple partial seizure 2 | 26
Skin cancer 2 | 469
Substance Withdrawal Syndrome 2 | 55
Substance abuse 2 | 59
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
pancreatic cancer 2 | 2,398
Arsenic Poisoning 1 | 62
Colorectal Neoplasms 1 | 243
Dermatologic disorders 1 | 93
Distal amyotrophy 1 | 51
Distal sensory impairment 1 | 52
Fragile X syndrome 1 | 34
Long QT syndrome 1 1 | 20
Myocardial Infarction 1 | 151
Nerve Degeneration 1 | 121
Rubinstein-Taybi syndrome 1 | 10
Skin Diseases 1 | 71
Somatic mutation 1 | 61
Testicular cancer 1 | 25
West Syndrome 1 | 28

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Liver and Pancreas 13 | 16,750
Nervous System 13 | 16,725
Skin and soft tissues 13 | 17,230
Female tissues 12 | 17,400
Male tissues 12 | 17,142
Respiratory system 12 | 16,393
Urinary Tract 12 | 16,678
Cardiovascular System 10 | 15,192

Target Family

Ion Channel 5 | 344
Kinase 4 | 634
Non-IDG 2 | 12,091
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

Reactome Pathway

CREB phosphorylation through t... 13 | 13
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
Calcium/calmodulin-dependent protein kinase type II subunit beta CAMK2B Tchem Kinase -1.14550 13.6 344
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.82317 50.9 620
Glutamate receptor ionotropic, NMDA 2C GRIN2C Tclin Ion Channel -2.21470 153.6 208
A-kinase anchor protein 9 AKAP9 Tbio Enzyme -2.22554 169.7 142
Glutamate receptor ionotropic, NMDA 2A GRIN2A Tclin Ion Channel -3.09828 1158.1 555
Calcium/calmodulin-dependent protein kinase type II subunit delta CAMK2D Tchem Kinase -1.37613 16.9 229
Glutamate receptor ionotropic, NMDA 2D GRIN2D Tclin Ion Channel -2.11112 128.4 110
Glutamate receptor ionotropic, NMDA 1 GRIN1 Tclin Ion Channel -2.84574 693.1 873
Neurofilament light polypeptide NEFL Tbio Non-IDG 0.00000 543