Development Level

Tbio 25 | 11,445
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
hypoactivity 3 | 132
abnormal behavior 2 | 298
abnormal body wall morphology 2 | 9
abnormal embryo size 2 | 220
embryonic lethality prior to o... 2 | 239
abnormal craniofacial morpholo... 1 | 33
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal skin morphology 1 | 50
absent startle reflex 1 | 24
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
enlarged spleen 1 | 41
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased or absent threshold ... 1 | 101
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
protruding tongue 1 | 3

Disease

ovarian cancer 21 | 8,520
psoriasis 9 | 6,694
Multiple myeloma 8 | 1,332
osteosarcoma 8 | 7,950
lung cancer 7 | 4,740
medulloblastoma, large-cell 7 | 6,241
Carcinoma 6 | 11,493
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
Breast cancer 4 | 3,578
ependymoma 4 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
oligodendroglioma 4 | 2,850
progressive supranuclear palsy 4 | 676
spina bifida 4 | 1,074
ulcerative colitis 4 | 1,819
Cancer 3 | 2,499
acute myeloid leukemia 3 | 783
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
dermatomyositis 3 | 966
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
primary pancreatic ductal adenocarcinoma 3 | 1,109
tuberculosis 3 | 2,010
Anemia 2 | 365
Astrocytoma, Pilocytic 2 | 3,081
Cleft Palate 2 | 271
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Neurodegenerative disease 2 | 414
Pick disease 2 | 1,894
Pick's disease 2 | 15
Vascular disease 2 | 319
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
malignant mesothelioma 2 | 3,232
medulloblastoma 2 | 720
pancreatic cancer 2 | 2,398
primary Sjogren syndrome 2 | 735
subependymal giant cell astrocytoma 2 | 2,287
Acquired immunodeficiency syndrome 1 | 197
Apathy 1 | 16
Aphasia 1 | 26
Apraxias 1 | 27
Autosomal dominant Robinow syndrome 1 1 | 15
Autosomal recessive Robinow syndrome 1 | 27
CATARACT 16, MULTIPLE TYPES 1 | 15
Carcinoma, Non-Small-Cell Lung 1 | 107
Carcinoma, Squamous Cell 1 | 110
Cleft uvula 1 | 27
Danon disease 1 | 8
Deglutition Disorders 1 | 132
Dentin dysplasia 1 | 19
Dysgraphia 1 | 20
Dyslexia 1 | 43
Echolalia 1 | 12
Excess nuchal skin 1 | 30
Familial cancer of breast 1 | 12
Forgetful 1 | 40
Frontal release signs 1 | 3
Human immunodeficiency virus infectious disease 1 | 138
Intermediate coronary syndrome 1 | 11
Irritation - emotion 1 | 68
Kaposi's sarcoma 1 | 22
Keratoconjunctivitis sicca 1 | 25
Leukemia, Myeloid, Acute 1 | 105
Liddle syndrome 1 | 14
Memory Loss 1 | 40
Memory impairment 1 | 40
Muscle Cramp 1 | 55
Muscle Rigidity 1 | 49
Mutism 1 | 17
Myoclonus 1 | 74
Pain 1 | 103
Paralysed 1 | 42
Periventricular nodular heterotopia 1 | 30
Poor speech 1 | 37
Prevention of Cardiac Transplant Rejection 1 | 15
Prevention of Kidney Transplant Rejection 1 | 17
Prevention of Liver Transplant Rejection 1 | 15
Problems speaking 1 | 37
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Respiratory insufficiency due to muscle weakness 1 | 37
Restlessness 1 | 14
Severe Recalcitrant Psoriasis 1 | 12
Social disinhibition 1 | 14
Submucous cleft of hard palate 1 | 11
Tear film insufficiency 1 | 15
lingual-facial-buccal dyskinesia 1 | 13

Tissue

Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678

Target Family

Non-IDG 25 | 12,091
Enzyme 2 | 4,145

Reactome Pathway

Budding and maturation of HIV ... 27 | 27
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Charged multivesicular body protein 7 CHMP7 Tbio Non-IDG -0.61033 3.61 30
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Charged multivesicular body protein 3 CHMP3 Tbio Non-IDG -1.39658 35.6 64
Programmed cell death 6-interacting protein PDCD6IP Tbio Non-IDG -1.59404 35.1 216
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Charged multivesicular body protein 2b CHMP2B Tbio Non-IDG -1.71624 54.4 193
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Peptidyl-prolyl cis-trans isomerase A PPIA Tclin Enzyme -2.97822 870.7 436
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139