Development Level

Tdark 24 | 7,003
Tbio 5 | 10,625
Tchem 3 | 1,890

Disease

diabetes mellitus 6 | 1,663
ovarian cancer 6 | 8,492
ulcerative colitis 5 | 2,087
Pneumonia 4 | 133
lung cancer 4 | 4,473
osteosarcoma 4 | 7,933
psoriasis 4 | 6,685
Asthma 3 | 349
Breast cancer 3 | 3,099
Cancer 3 | 2,346
IGA Glomerulonephritis 3 | 454
Otitis media 3 | 32
Tonsillitis 3 | 18
cutaneous lupus erythematosus 3 | 1,056
cystic fibrosis 3 | 1,670
glioblastoma 3 | 5,572
interstitial cystitis 3 | 2,299
lung carcinoma 3 | 2,844
periodontitis 3 | 269
tuberculosis 3 | 1,563
Acne 2 | 20
Arthritis 2 | 248
Atherosclerosis 2 | 275
Atopic dermatitis 2 | 944
Atrioventricular septal defect 2 | 14
Bacterial vaginosis 2 | 15
Candidiasis 2 | 48
Common cold 2 | 63
Congenital diaphragmatic hernia 2 | 44
Dermatitis 2 | 141
Hypersensitivity 2 | 63
Hypersensitivity reaction type II disease 2 | 235
Inflammatory bowel disease 2 | 142
Keratitis 2 | 42
Kidney disease 2 | 397
Leprosy 2 | 77
Lyme disease 2 | 23
Mastitis 2 | 48
Obesity 2 | 616
Rheumatoid Arthritis 2 | 1,171
hepatocellular carcinoma 2 | 550
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
invasive ductal carcinoma 2 | 2,950
medulloblastoma, large-cell 2 | 6,234
pancreatic cancer 2 | 2,300
pilocytic astrocytoma 2 | 3,086
urothelial carcinoma 2 | 318
ventricular septal defect 2 | 20
Acquired immunodeficiency syndrome 1 | 164
Age related macular degeneration 1 | 84
Allergic hypersensitivity disease 1 | 123
Bipolar Disorder 1 | 266
Carcinoma of colon 1 | 32
Cardiomyopathies 1 | 90
Celiac disease 1 | 112
Cholesteatoma 1 | 13
Chronic obstructive pulmonary disease 1 | 147
Colorectal Neoplasms 1 | 217
Contact Dermatitis 1 | 80
Coronary artery disease 1 | 240
Dermatitis, Allergic Contact 1 | 66
Dermatophytosis 1 | 12
Drug-Induced Liver Injury 1 | 118
Filariasis 1 | 21
Human immunodeficiency virus infectious disease 1 | 129
Infertility 1 | 163
Inflammation 1 | 109
Inflammatory Bowel Diseases 1 | 87
Influenza 1 | 142
Leishmaniasis 1 | 49
Leptospirosis 1 | 17
Liver disease 1 | 219
Liver diseases 1 | 66
Lung disease 1 | 136
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding) 1 | 12
Malaria 1 | 140
Male infertility 1 | 170
Meningitis 1 | 46
Multiple Sclerosis 1 | 498
Neurodegenerative disease 1 | 383
Peritonitis 1 | 37
Pulmonary Fibrosis 1 | 66
Reperfusion Injury 1 | 84
Status Epilepticus 1 | 85
Tinea pedis 1 | 30
Tularemia 1 | 22
Vitiligo 1 | 71
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 918
adult high grade glioma 1 | 2,148
breast carcinoma 1 | 1,614
chronic kidney disease 1 | 90
chronic rhinosinusitis 1 | 512
head and neck cancer 1 | 270
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
non-inflammatory breast cancer 1 | 208
pancreatic carcinoma 1 | 567
pituitary cancer 1 | 1,972
pulmonary tuberculosis 1 | 8
sarcoidosis 1 | 368

Tissue

Female tissues 20 | 18,647
Nervous System 19 | 18,561
Urinary Tract 18 | 18,444
Endocrine System 17 | 18,512
Digestive Tract 16 | 18,473
Cardiovascular System 13 | 17,958
Male tissues 13 | 17,969
Liver and Pancreas 12 | 18,136
Skin and soft tissues 12 | 18,115
Blood and immune system 10 | 17,995
Respiratory system 7 | 17,484

Target Family

Non-IDG 30 | 11,969
GPCR 2 | 408

Reactome Pathway

Beta defensins 32 | 32
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-defensin 118 DEFB118 Tdark Non-IDG -0.54407 3.57 6
C-C chemokine receptor type 2 CCR2 Tchem GPCR -3.03237 1034.3 447
Beta-defensin 126 DEFB126 Tbio Non-IDG -1.29871 21.4 11
Putative beta-defensin 108A DEFB108P1 Tdark Non-IDG 0.01 1.31 0
C-C chemokine receptor type 6 CCR6 Tchem GPCR -1.79196 58.1 422
Beta-defensin 135 DEFB135 Tdark Non-IDG 0.78 0.14 5
Beta-defensin 136 DEFB136 Tdark Non-IDG 0.00000 3
Beta-defensin 133 DEFB133 Tdark Non-IDG 0.00000 6
Beta-defensin 110 DEFB110 Tdark Non-IDG 0.34 0.44 9
Beta-defensin 114 DEFB114 Tbio Non-IDG -0.60687 5.88 5