Development Level

Tdark 24 | 7,003
Tbio 5 | 10,625
Tchem 3 | 1,890

Disease

diabetes mellitus 6 | 1,663
ovarian cancer 6 | 8,491
ulcerative colitis 5 | 2,087
Pneumonia 4 | 133
lung cancer 4 | 4,473
osteosarcoma 4 | 7,933
psoriasis 4 | 6,685
Asthma 3 | 349
Breast cancer 3 | 3,098
Cancer 3 | 2,346
IGA Glomerulonephritis 3 | 454
Otitis media 3 | 32
Tonsillitis 3 | 18
cutaneous lupus erythematosus 3 | 1,056
cystic fibrosis 3 | 1,670
glioblastoma 3 | 5,572
interstitial cystitis 3 | 2,299
lung carcinoma 3 | 2,844
periodontitis 3 | 269
tuberculosis 3 | 1,563
Acne 2 | 20
Arthritis 2 | 248
Atherosclerosis 2 | 275
Atopic dermatitis 2 | 944
Atrioventricular septal defect 2 | 14
Bacterial vaginosis 2 | 15
Candidiasis 2 | 48
Common cold 2 | 63
Congenital diaphragmatic hernia 2 | 44
Dermatitis 2 | 141
Hypersensitivity 2 | 63
Hypersensitivity reaction type II disease 2 | 235
Inflammatory bowel disease 2 | 142
Keratitis 2 | 42
Kidney disease 2 | 397
Leprosy 2 | 77
Lyme disease 2 | 23
Mastitis 2 | 48
Obesity 2 | 616
Rheumatoid Arthritis 2 | 1,170
hepatocellular carcinoma 2 | 550
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
invasive ductal carcinoma 2 | 2,950
medulloblastoma, large-cell 2 | 6,234
pancreatic cancer 2 | 2,300
pilocytic astrocytoma 2 | 3,086
urothelial carcinoma 2 | 318
ventricular septal defect 2 | 20
Acquired immunodeficiency syndrome 1 | 164
Age related macular degeneration 1 | 84
Allergic hypersensitivity disease 1 | 123
Bipolar Disorder 1 | 266
Carcinoma of colon 1 | 32
Cardiomyopathies 1 | 90
Celiac disease 1 | 112
Cholesteatoma 1 | 13
Chronic obstructive pulmonary disease 1 | 147
Colorectal Neoplasms 1 | 217
Contact Dermatitis 1 | 80
Coronary artery disease 1 | 240
Dermatitis, Allergic Contact 1 | 66
Dermatophytosis 1 | 12
Drug-Induced Liver Injury 1 | 118
Filariasis 1 | 21
Human immunodeficiency virus infectious disease 1 | 129
Infertility 1 | 163
Inflammation 1 | 109
Inflammatory Bowel Diseases 1 | 87
Influenza 1 | 142
Leishmaniasis 1 | 49
Leptospirosis 1 | 17
Liver disease 1 | 219
Liver diseases 1 | 66
Lung disease 1 | 136
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding) 1 | 12
Malaria 1 | 140
Male infertility 1 | 170
Meningitis 1 | 46
Multiple Sclerosis 1 | 498
Neurodegenerative disease 1 | 383
Peritonitis 1 | 37
Pulmonary Fibrosis 1 | 66
Reperfusion Injury 1 | 84
Status Epilepticus 1 | 85
Tinea pedis 1 | 30
Tularemia 1 | 22
Vitiligo 1 | 71
Waldenstrons macroglobulinemia 1 | 764
active Crohn's disease 1 | 918
adult high grade glioma 1 | 2,148
breast carcinoma 1 | 1,614
chronic kidney disease 1 | 90
chronic rhinosinusitis 1 | 512
head and neck cancer 1 | 270
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
non-inflammatory breast cancer 1 | 208
pancreatic carcinoma 1 | 567
pituitary cancer 1 | 1,972
pulmonary tuberculosis 1 | 8
sarcoidosis 1 | 368

Tissue

Female tissues 20 | 18,646
Nervous System 19 | 18,560
Urinary Tract 18 | 18,443
Endocrine System 17 | 18,511
Digestive Tract 16 | 18,472
Cardiovascular System 13 | 17,957
Male tissues 13 | 17,968
Liver and Pancreas 12 | 18,135
Skin and soft tissues 12 | 18,114
Blood and immune system 10 | 17,994
Respiratory system 7 | 17,483

Target Family

Non-IDG 30 | 11,969
GPCR 2 | 408

Reactome Pathway

Beta defensins 32 | 32
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Toll-like receptor 2 TLR2 Tchem Non-IDG -3.47133 3173.5 946
Beta-defensin 119 DEFB119 Tdark Non-IDG -0.12494 1.33 42
Beta-defensin 123 DEFB123 Tdark Non-IDG -0.53360 3.65 0
Beta-defensin 125 DEFB125 Tdark Non-IDG 0.12 0.82 6
Beta-defensin 134 DEFB134 Tdark Non-IDG 0.18 0.57 6
Beta-defensin 127 DEFB127 Tdark Non-IDG -0.64836 4.65 5
Beta-defensin 129 DEFB129 Tdark Non-IDG -0.04139 1.53 22
Beta-defensin 1 DEFB1 Tbio Non-IDG -2.61974 414.0 305
Beta-defensin 108B DEFB108B Tdark Non-IDG 0.01 1.31 9
Beta-defensin 124 DEFB124 Tdark Non-IDG 0.27 0.67 16