Development Level

Tdark 17 | 6,593
Tbio 11 | 11,651
Tchem 2 | 1,388

IMPC Phenotype

abnormal vibrissa morphology 1 | 25
decreased heart rate 1 | 18
increased mean corpuscular vol... 1 | 92
prolonged RR interval 1 | 8

Disease

Carcinoma 7 | 11,493
diabetes mellitus 6 | 1,728
ovarian cancer 5 | 8,520
Breast cancer 4 | 3,578
Inflammatory bowel disease 3 | 151
Otitis Media 3 | 52
Pneumonia 3 | 174
Tonsillitis 3 | 16
cystic fibrosis 3 | 1,696
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
periodontitis 3 | 293
psoriasis 3 | 6,694
ulcerative colitis 3 | 1,819
Acne 2 | 52
Adverse reaction to drug 2 | 61
Arthritis 2 | 290
Arthritis, Rheumatoid 2 | 174
Astrocytoma, Pilocytic 2 | 3,081
Atrioventricular Septal Defect 2 | 22
Bacterial vaginosis 2 | 15
Bipolar Disorder 2 | 666
Brain Injuries 2 | 65
Cancer 2 | 2,499
Candidiasis 2 | 55
Common cold 2 | 69
Congenital diaphragmatic hernia 2 | 67
Dermatitis 2 | 157
Drug-Related Side Effects and Adverse Reactions 2 | 62
Keratitis 2 | 62
Leprosy 2 | 73
Lyme disease 2 | 26
Mastitis 2 | 48
Rheumatoid arthritis 2 | 1,191
cutaneous lupus erythematosus 2 | 1,057
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
tuberculosis 2 | 2,010
urothelial carcinoma 2 | 318
ventricular septal defect 2 | 20
Arthralgia 1 | 90
Autoimmune Diseases 1 | 67
Carcinoma of colon 1 | 32
Cardiomyopathies 1 | 110
Cerebrovascular disease 1 | 238
Chagas disease 1 | 39
Cholestasis 1 | 155
Cholesteatoma 1 | 16
Colorectal Neoplasms 1 | 243
Contracture 1 | 96
Contracture of joint 1 | 93
Deglutition Disorders 1 | 132
Dental caries 1 | 164
Dyspareunia 1 | 12
Dyspnea 1 | 76
Eosinophilia 1 | 28
Filariasis 1 | 21
Flexion contracture 1 | 93
Flexion contractures of joints 1 | 93
Gastritis 1 | 47
Gastroesophageal reflux disease 1 | 110
Heartburn 1 | 78
Human immunodeficiency virus infectious disease 1 | 138
Hypersensitivity 1 | 63
Infiltrate of lung 1 | 17
Inflammation 1 | 120
Inflammatory Bowel Diseases 1 | 35
Influenza 1 | 142
Kidney disease 1 | 430
Leishmaniasis 1 | 47
Leptospirosis 1 | 18
Liver disease 1 | 237
Lytic lesion 1 | 32
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO 1 | 11
Malabsorption 1 | 82
Malaria 1 | 160
Meningitis 1 | 67
Muscle Weakness 1 | 170
Nausea and vomiting 1 | 97
Neurodegenerative disease 1 | 414
Perinatal necrotizing enterocolitis 1 | 21
Peritonitis 1 | 43
Plague 1 | 19
Pneumonia, Pneumococcal 1 | 6
Pulmonary Fibrosis 1 | 106
Reperfusion Injury 1 | 86
Rotting teeth 1 | 73
Skin Ulcer 1 | 48
Streptococcal pneumonia 1 | 6
Telangiectasia of the skin 1 | 39
Tinea pedis 1 | 29
Tularemia 1 | 23
Vitiligo 1 | 73
active ulcerative colitis 1 | 764
hypopigmented skin patch 1 | 59
pulmonary tuberculosis 1 | 9
substance-related disorder 1 | 162

Tissue

Male tissues 27 | 17,142
Endocrine System 14 | 18,159
Skin and soft tissues 10 | 17,230
Digestive Tract 9 | 17,369
Female tissues 8 | 17,400
Liver and Pancreas 7 | 16,750
Blood and immune system 6 | 16,909
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Urinary Tract 6 | 16,678
Cardiovascular System 3 | 15,192

Target Family

Non-IDG 29 | 12,091
GPCR 1 | 408

Reactome Pathway

Beta defensins 30 | 30
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-C chemokine receptor type 6 CCR6 Tchem GPCR -1.81445 63.7 519
Beta-defensin 4A DEFB4A Tbio Non-IDG -2.72493 88.3 132
Beta-defensin 1 DEFB1 Tbio Non-IDG -2.65365 445.4 355
Beta-defensin 121 DEFB121 Tdark Non-IDG 0.48 0.33 45
Beta-defensin 127 DEFB127 Tbio Non-IDG -0.65801 4.72 3
Beta-defensin 130B DEFB130A Tdark Non-IDG 0.48 0.50 0
Beta-defensin 130A DEFB130A Tbio Non-IDG 0.48 0.50 0
Beta-defensin 108B DEFB108B Tdark Non-IDG 0.01 1.30 10
Beta-defensin 124 DEFB124 Tbio Non-IDG 0.27 0.76 17
Beta-defensin 129 DEFB129 Tdark Non-IDG -0.20412 1.03 30