Development Level

Tbio 8 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

decreased blood urea nitrogen ... 1 | 51
increased circulating alkaline... 1 | 122

Disease

osteosarcoma 6 | 7,950
Cancer 5 | 2,499
group 3 medulloblastoma 5 | 4,104
Carcinoma 4 | 11,493
lung cancer 4 | 4,740
Autosomal recessive predisposition 3 | 1,442
medulloblastoma, large-cell 3 | 6,241
tuberculosis 3 | 2,010
Adenoma 2 | 167
Adenomatous Polyposis Coli 2 | 16
Cockayne syndrome 2 | 60
Colorectal adenoma 2 | 15
Xeroderma pigmentosum group G 2 | 16
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
glioblastoma 2 | 5,792
malignant mesothelioma 2 | 3,232
ovarian cancer 2 | 8,520
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
Acquired immunodeficiency syndrome 1 | 197
Adenocarcinoma 1 | 122
Adenocarcinoma of lung 1 | 142
Adenocarcinoma of lung (disorder) 1 | 60
Aphasia 1 | 26
Apraxia 1 | 26
Arthropathy 1 | 43
Asbestosis 1 | 20
Bloom syndrome 1 | 29
Brain Diseases 1 | 24
Carcinoma of colon 1 | 32
Carcinoma, Renal Cell 1 | 124
Chromosome Aberrations 1 | 16
Colorectal Adenomatous Polyposis, Autosomal Recessive 1 | 1
Colorectal Neoplasms 1 | 243
Dermatologic disorders 1 | 93
Dyslipidemias 1 | 27
Encephalitis 1 | 64
Epididymitis 1 | 8
Familial adenomatous polyposis 1 | 32
Fatty Liver 1 | 70
Fibrous dysplasia 1 | 15
Frontotemporal dementia 1 | 51
Gastric Cancer, Hereditary Diffuse 1 | 12
Gastrointestinal system disease 1 | 54
Glucose Intolerance 1 | 19
Hearing Loss, Noise-Induced 1 | 5
Heart Diseases 1 | 43
Hemangioma 1 | 69
Hyperinsulinism 1 | 133
Hyperlipidemia 1 | 43
IgG Deficiency 1 | 22
Immunoglobulin A deficiency (disorder) 1 | 19
Immunologic Deficiency Syndromes 1 | 113
Impaired Ig class-switch recombination (CSR) 1 | 3
Impaired glucose tolerance 1 | 28
Increased IgM levels 1 | 16
Increased susceptibility to bacterial infections 1 | 42
Insulin Resistance 1 | 72
Intracranial hypotension 1 | 10
Isolated cases 1 | 72
Juvenile polyposis syndrome 1 | 7
Leiomyoma 1 | 32
Lymphadenopathy 1 | 62
Lymphatic system disease 1 | 15
Lymphoma 1 | 81
Lymphoproliferative syndrome 1 | 58
Lynch syndrome 1 | 35
Malignant neoplasm of skin 1 | 15
Measles 1 | 22
Meningioma 1 | 41
Metabolic Syndrome 1 | 20
Metabolic syndrome X 1 | 52
Motor Skills Disorders 1 | 8
Movement disease 1 | 11
Multiple colonic adenomatous polyps 1 | 3
Multiple system atrophy 1 | 29
Neoplasm of stomach 1 | 11
Nerve Degeneration 1 | 121
Neurilemmoma 1 | 23
Noise-induced hearing loss 1 | 5
Pancreatitis 1 | 123
Papilledema 1 | 11
Peutz-Jeghers syndrome 1 | 21
Pilomatrixoma 1 | 12
Prenatal Injuries 1 | 11
Prone to bacterial infection 1 | 42
Recurrent bacterial infection 1 | 42
Renal Cell Carcinoma 1 | 214
Renal Cell Carcinoma, Nonpapillary 1 | 7
Skin Diseases 1 | 71
Skin Neoplasms 1 | 69
Somatic mutation 1 | 61
Stomach Carcinoma 1 | 11
Takayasu's arteritis 1 | 53
Thyroiditis 1 | 29
Urologic Neoplasms 1 | 8
Xeroderma pigmentosum group D 1 | 33
Xeroderma pigmentosum group F 1 | 22
sarcoidosis 1 | 370

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Enzyme 9 | 4,145

Reactome Pathway

Base-Excision Repair, AP Site ... 9 | 9
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endonuclease III-like protein 1 NTHL1 Tbio Enzyme -1.85066 66.8 155
Adenine DNA glycosylase MUTYH Tbio Enzyme -2.86910 750.8 255
G/T mismatch-specific thymine DNA glycosylase TDG Tbio Enzyme -2.46252 297.6 225
Single-strand selective monofunctional uracil DNA glycosylase SMUG1 Tbio Enzyme -4.31831 20587.4 199
Uracil-DNA glycosylase UNG Tbio Enzyme -2.82957 680.9 352
N-glycosylase/DNA lyase OGG1 Tbio Enzyme -3.26147 1834.9 293
Endonuclease 8-like 2 NEIL2 Tbio Enzyme -1.74921 49.0 107
DNA-3-methyladenine glycosylase MPG Tchem Enzyme -2.84708 687.5 316
Endonuclease 8-like 1 NEIL1 Tbio Enzyme -2.01238 106.1 202