Development Level

Tbio 17 | 11,445
Tchem 6 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased fasted circulating g... 3 | 65
decreased total body fat amoun... 3 | 207
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
decreased neutrophil cell numb... 2 | 42
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased lean body mass 2 | 172
pale yolk sac 2 | 25
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal brain morphology 1 | 13
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged uterus 1 | 11
hydroencephaly 1 | 14
hydrometra 1 | 53
hyperactivity 1 | 148
impaired righting response 1 | 26
increased circulating alkaline... 1 | 122
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
pallor 1 | 34
small superior vagus ganglion 1 | 74

Disease

Carcinoma 21 | 11,493
ovarian cancer 21 | 8,520
osteosarcoma 20 | 7,950
medulloblastoma, large-cell 17 | 6,241
psoriasis 17 | 6,694
glioblastoma 16 | 5,792
Cancer 12 | 2,499
atypical teratoid / rhabdoid tumor 12 | 5,112
malignant mesothelioma 12 | 3,232
adult high grade glioma 11 | 3,801
ependymoma 11 | 4,679
lung cancer 11 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
pituitary cancer 10 | 1,972
group 3 medulloblastoma 9 | 4,104
astrocytoma 8 | 1,146
diabetes mellitus 8 | 1,728
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
invasive ductal carcinoma 8 | 2,951
primitive neuroectodermal tumor 8 | 3,035
Bipolar Disorder 7 | 666
Breast cancer 7 | 3,578
Kidney cancer 7 | 2,613
Prostatic Neoplasms 7 | 495
acute quadriplegic myopathy 7 | 1,158
pancreatic cancer 7 | 2,398
Pick disease 6 | 1,894
Schizophrenia 6 | 1,160
astrocytic glioma 6 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
non-small cell lung cancer 6 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
tuberculosis 6 | 2,010
Autistic Disorder 5 | 364
Hypertension 5 | 396
Obesity 5 | 678
Rheumatoid arthritis 5 | 1,191
gastric carcinoma 5 | 807
oligodendroglioma 5 | 2,850
Astrocytoma, Pilocytic 4 | 3,081
Atherosclerosis 4 | 291
Atopic dermatitis 4 | 952
acute myeloid leukemia 4 | 783
lung carcinoma 4 | 2,843
non primary Sjogren syndrome sicca 4 | 891
Cerebrovascular disease 3 | 238
Coronary artery disease 3 | 268
Endometriosis 3 | 540
Fatty liver disease 3 | 103
Heart disease 3 | 306
Hypertensive disease 3 | 292
Lipid metabolism disorder 3 | 114
Liver disease 3 | 237
Major Depressive Disorder 3 | 301
Multiple myeloma 3 | 1,332
Unipolar Depression 3 | 250
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
primary pancreatic ductal adenocarcinoma 3 | 1,109
ulcerative colitis 3 | 1,819
Breast Neoplasms 2 | 445
Cardiac Arrhythmia 2 | 103
Chemical and Drug Induced Liver Injury 2 | 195
Chronic Lymphocytic Leukemia 2 | 262
Depressive disorder 2 | 409
Disease Models, Animal 2 | 155
Heart failure 2 | 162
Highly variable severity 2 | 157
Hyperinsulinism 2 | 133
Hypoglycemia 2 | 152
Kidney Diseases 2 | 114
Kidney disease 2 | 430
Liver Cirrhosis 2 | 181
Liver Cirrhosis, Experimental 2 | 769
Liver neoplasms 2 | 130
Lung disease 2 | 142
Mammary Neoplasms 2 | 425
Mammary Neoplasms, Experimental 2 | 154
Mental Depression 2 | 333
Mesothelioma, Malignant 2 | 105
Polycystic ovary syndrome 2 | 360
Pulmonary embolism 2 | 55
Systemic lupus erythematosus 2 | 194
Variable expressivity 2 | 157
active ulcerative colitis 2 | 764
colon cancer 2 | 1,478
dermatomyositis 2 | 966
gastric cancer 2 | 459
head and neck cancer 2 | 271
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
urothelial carcinoma 2 | 318

Tissue

Endocrine System 26 | 18,159
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678
Blood and immune system 25 | 16,909
Cardiovascular System 25 | 15,192
Digestive Tract 25 | 17,369
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 24 | 16,393

Target Family

Non-IDG 8 | 12,091
Transcription Factor 6 | 1,400
Enzyme 5 | 4,145
Epigenetic 4 | 242
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

Reactome Pathway

BMAL1:CLOCK,NPAS2 activates ci... 26 | 26
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-arginine methyltransferase CARM1 CARM1 Tchem Epigenetic -2.04034 130.8 476
D site-binding protein DBP Tbio Transcription Factor -1.50821 28.6 93
Helicase with zinc finger domain 2 HELZ2 Tdark Enzyme -0.50849 4.27 30
Trimethylguanosine synthase TGS1 Tbio Enzyme -1.40283 26.5 103
Chromodomain-helicase-DNA-binding protein 9 CHD9 Tbio Epigenetic -0.90481 7.77 30
Class E basic helix-loop-helix protein 40 BHLHE40 Tbio Transcription Factor -1.77841 66.6 224
Class E basic helix-loop-helix protein 41 BHLHE41 Tbio Transcription Factor -2.02777 112.1 254
Nuclear receptor coactivator 6 NCOA6 Tbio Non-IDG -1.83369 72.1 54
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 SMARCD3 Tbio Non-IDG -1.30404 22.1 170