Development Level

Tbio 17 | 11,445
Tchem 7 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal tail morphology 1 | 25
embryonic lethality prior to t... 1 | 278
increased grip strength 1 | 41
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 16 | 8,520
Carcinoma 15 | 11,493
Breast cancer 10 | 3,578
medulloblastoma, large-cell 10 | 6,241
lung cancer 9 | 4,740
osteosarcoma 9 | 7,950
Cancer 8 | 2,499
glioblastoma 7 | 5,792
pancreatic cancer 7 | 2,398
psoriasis 7 | 6,694
Waldenstrons macroglobulinemia 6 | 765
Huntington's disease 5 | 76
Major Depressive Disorder 5 | 301
Multiple myeloma 5 | 1,332
adult high grade glioma 5 | 3,801
astrocytoma 5 | 1,146
atypical teratoid / rhabdoid tumor 5 | 5,112
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Astrocytoma, Pilocytic 4 | 3,081
Hypoplastic mandible condyle 4 | 275
Kidney cancer 4 | 2,613
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Schizophrenia 4 | 1,160
Unipolar Depression 4 | 250
esophageal adenocarcinoma 4 | 737
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
pancreatic carcinoma 4 | 562
pituitary cancer 4 | 1,972
Acquired scoliosis 3 | 281
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Carcinoma, Squamous Cell 3 | 110
Cataract 3 | 297
Curvature of spine 3 | 282
Epilepsy 3 | 792
HIV Infections 3 | 102
Joint laxity 3 | 54
Lens Opacities 3 | 231
Mammary Neoplasms 3 | 425
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
Short stature 3 | 531
Squamous cell carcinoma 3 | 129
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
chronic rhinosinusitis 3 | 512
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
malignant mesothelioma 3 | 3,232
Acquired flat foot 2 | 72
Agoraphobia 2 | 21
Angle class 3 malocclusion 2 | 57
Auricular malformation 2 | 41
Broad thumbs 2 | 28
Corneal abnormalities 2 | 6
Cornela disease 2 | 6
Decreased projection of maxilla 2 | 66
Defective enamel matrix 2 | 35
Deficiency of upper jaw bones 2 | 66
Dental Enamel Hypoplasia 2 | 43
Dental caries 2 | 164
Duane Retraction Syndrome 2 | 13
Dysplasia of tooth enamel 2 | 35
Enophthalmos 2 | 75
Flared iliac wings 2 | 13
Flatfoot 2 | 73
Hirsutism 2 | 47
Hyperactive behavior 2 | 91
Hyperplasia of foramen magnum 2 | 6
Hypoplasia of the maxilla 2 | 66
Hypotrophic maxilla 2 | 66
Increased circumference of foramen magnum 2 | 6
Increased diameter of foramen magnum 2 | 6
Keloid 2 | 37
Large foramen magnum 2 | 6
Legg-Calve-Perthes disease 2 | 14
Low posterior hairline 2 | 52
Malocclusion 2 | 57
Maxillary retrognathia 2 | 66
Phonophobia 2 | 11
Poor coordination 2 | 11
Recurrent upper respiratory tract infection 2 | 21
Retrusion of upper jaw bones 2 | 66
Self Mutilation 2 | 14
Simple ear 2 | 41
Spina bifida occulta 2 | 19
Sunken eyes 2 | 63
Thin dental enamel 2 | 35

Tissue

Blood and immune system 25 | 16,909
Endocrine System 25 | 18,159
Digestive Tract 24 | 17,369
Male tissues 24 | 17,142
Respiratory system 23 | 16,393
Urinary Tract 23 | 16,678
Female tissues 22 | 17,400
Nervous System 22 | 16,725
Skin and soft tissues 22 | 17,230
Cardiovascular System 21 | 15,192
Liver and Pancreas 21 | 16,750

Target Family

Non-IDG 20 | 12,091
Enzyme 2 | 4,145
Epigenetic 2 | 242
Transcription Factor 1 | 1,400

Reactome Pathway

Attenuation phase 25 | 25
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA-binding death effector domain-containing protein 2 DEDD2 Tbio Non-IDG -0.55115 3.37 164
Heat shock-related 70 kDa protein 2 HSPA2 Tbio Non-IDG -1.98655 104.3 162
Heat shock 70 kDa protein 1A HSPA1B Tchem Non-IDG -3.10995 0.00000 1174
Heat shock 70 kDa protein 1B HSPA1B Tbio Non-IDG -1.61862 0.00000 60
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Serpin H1 SERPINH1 Tbio Non-IDG -3.18763 1526.9 346
Heat shock 70 kDa protein 6 HSPA6 Tbio Non-IDG -1.75259 92.5 173
Heat shock factor-binding protein 1 HSBP1 Tbio Non-IDG -0.97962 10.1 68
Tumor necrosis factor receptor superfamily member 21 TNFRSF21 Tbio Non-IDG -2.23109 178.7 413
Heat shock protein 105 kDa HSPH1 Tbio Non-IDG -1.69371 52.4 316