Development Level

Tbio 142 | 11,445
Tchem 14 | 1,598
Tclin 6 | 613
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 3 | 499
decreased blood urea nitrogen ... 2 | 51
decreased circulating amylase ... 2 | 28
decreased lymphocyte cell numb... 2 | 83
decreased total body fat amoun... 2 | 207
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal cecum morphology 1 | 7
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged uterus 1 | 11
hypoactivity 1 | 132
impaired righting response 1 | 26
increased CD4-positive, alpha ... 1 | 4
increased bone mineral content 1 | 108
increased circulating amylase ... 1 | 25
increased eosinophil cell numb... 1 | 11
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Cancer 96 | 2,499
psoriasis 96 | 6,694
diabetes mellitus 79 | 1,728
Carcinoma 76 | 11,493
ovarian cancer 74 | 8,520
Ankylosing spondylitis 72 | 140
Behcet's disease 70 | 89
Arthritis 65 | 290
Hypersensitivity reaction type II disease 60 | 253
Uveitis 58 | 103
dermatomyositis 58 | 966
Acquired immunodeficiency syndrome 56 | 197
Herpes zoster 56 | 68
Juvenile rheumatoid arthritis 56 | 111
Human immunodeficiency virus infectious disease 52 | 138
Stevens-Johnson syndrome 51 | 92
Psoriatic arthritis 49 | 86
glioblastoma 49 | 5,792
lung cancer 49 | 4,740
osteosarcoma 49 | 7,950
Rheumatoid arthritis 45 | 1,191
tuberculosis 44 | 2,010
Dermatitis 38 | 157
Multiple myeloma 38 | 1,332
Behcet's syndrome 36 | 50
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 78
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
lung carcinoma 29 | 2,843
medulloblastoma, large-cell 28 | 6,241
Astrocytoma, Pilocytic 27 | 3,081
Kidney disease 27 | 430
Anemia 25 | 365
Multiple Sclerosis 25 | 540
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
Leprosy 23 | 73
Liver disease 23 | 237
Birdshot chorioretinopathy 22 | 23
Hemochromatosis 22 | 54
Hepatitis B 22 | 108
Primary immunodeficiency disease 22 | 54
Skin disease 22 | 66
cutaneous lupus erythematosus 22 | 1,057
invasive ductal carcinoma 22 | 2,951
juvenile dermatomyositis 22 | 1,187
subependymal giant cell astrocytoma 22 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
adult high grade glioma 20 | 3,801
ependymoma 20 | 4,679
Breast cancer 19 | 3,578
astrocytoma 19 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
malignant mesothelioma 19 | 3,232
non-small cell lung cancer 18 | 2,890
HIV Infections 17 | 102
Pre-Eclampsia 16 | 68
pancreatic cancer 16 | 2,398
atypical teratoid / rhabdoid tumor 15 | 5,112
interstitial cystitis 15 | 2,312
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Psoriasis susceptibility 1 14 | 14
Liver Cirrhosis, Experimental 13 | 769
Waldenstrons macroglobulinemia 13 | 765
group 4 medulloblastoma 13 | 1,855
ulcerative colitis 13 | 1,819
primary Sjogren syndrome 12 | 735
active Crohn's disease 11 | 922
group 3 medulloblastoma 11 | 4,104
lung adenocarcinoma 11 | 2,716
Autosomal recessive predisposition 10 | 1,442
Duchenne muscular dystrophy 10 | 601
Schizophrenia 10 | 1,160
esophageal adenocarcinoma 10 | 737
astrocytic glioma 9 | 2,597
cystic fibrosis 9 | 1,696
oligodendroglioma 9 | 2,850
Bipolar Disorder 7 | 666
Fever 7 | 138
Hypertension 7 | 396
Hypertensive disease 7 | 292
Obesity 7 | 678
Otitis Media 7 | 52
acute quadriplegic myopathy 7 | 1,158
adrenocortical carcinoma 7 | 1,428
pituitary cancer 7 | 1,972
Atherosclerosis 6 | 291
Atopic dermatitis 6 | 952
Diarrhea 6 | 253
Pick disease 6 | 1,894
active ulcerative colitis 6 | 764
breast carcinoma 6 | 1,638
mucosa-associated lymphoid tissue lymphoma 6 | 484
periodontitis 6 | 293
primary pancreatic ductal adenocarcinoma 6 | 1,109
primitive neuroectodermal tumor 6 | 3,035

Tissue

Endocrine System 97 | 18,159
Digestive Tract 96 | 17,369
Female tissues 96 | 17,400
Respiratory system 96 | 16,393
Blood and immune system 95 | 16,909
Liver and Pancreas 95 | 16,750
Male tissues 95 | 17,142
Nervous System 95 | 16,725
Urinary Tract 95 | 16,678
Cardiovascular System 94 | 15,192
Skin and soft tissues 94 | 17,230

Target Family

Non-IDG 118 | 12,091
Enzyme 44 | 4,145
Kinase 4 | 634
Ion Channel 1 | 344

Reactome Pathway

Antigen processing-Cross prese... 167 | 167
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
C-type lectin domain family 4 member K CD207 Tbio Non-IDG -2.49714 321.5 295
HLA class I histocompatibility antigen, Cw-17 alpha chain HLA-C Tbio Non-IDG -1.90661 830.5 0
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
HLA class I histocompatibility antigen, Cw-15 alpha chain HLA-C Tbio Non-IDG -1.90661 830.5 0
Cytochrome b-245 heavy chain CYBB Tchem Ion Channel -3.09698 1276.8 315
Lymphocyte antigen 96 LY96 Tchem Non-IDG -2.77678 541.2 369