Development Level

Tbio 4 | 10,625
Tchem 2 | 1,890
Tdark 1 | 7,003

IMPC Phenotype

abnormal skin morphology 1 | 23
abnormal tooth morphology 1 | 24

Disease

malignant mesothelioma 6 | 3,163
Carcinoma 5 | 2,147
lung carcinoma 5 | 2,844
Epidermolysis bullosa 4 | 21
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
lung cancer 4 | 4,473
non-small cell lung cancer 4 | 2,798
ovarian cancer 4 | 8,491
Adult junctional epidermolysis bullosa (disorder) 3 | 5
Breast cancer 3 | 3,098
Epidermolysis bullosa, junctional, Herlitz type 3 | 3
Herlitz Disease 3 | 3
Junctional epidermolysis bullosa 3 | 9
breast carcinoma 3 | 1,614
esophageal adenocarcinoma 3 | 737
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
medulloblastoma, large-cell 3 | 6,234
pancreatic cancer 3 | 2,300
primary pancreatic ductal adenocarcinoma 3 | 1,271
Adult junctional epidermolysis bullosa 2 | 3
Barrett's esophagus 2 | 185
Epidermolysis bullosa dystrophica 2 | 6
Generalized junctional epidermolysis bullosa, non-Herlitz type 2 | 3
Osteogenesis imperfecta 2 | 34
active ulcerative colitis 2 | 477
atypical teratoid / rhabdoid tumor 2 | 4,369
glioblastoma 2 | 5,572
invasive ductal carcinoma 2 | 2,950
junctional epidermolysis bullosa Herlitz type 2 | 2
lung adenocarcinoma 2 | 2,714
non-small cell lung carcinoma 2 | 413
osteosarcoma 2 | 7,933
pediatric high grade glioma 2 | 2,712
psoriasis 2 | 6,685
Allergic rhinitis (disorder) 1 | 12
Amelogenesis imperfecta 1 | 26
Amelogenesis imperfecta 1A 1 | 1
Amelogenesis imperfecta local hypoplastic form 1 | 1
Amyotrophic Lateral Sclerosis 1 | 432
Atrial heart septal defect 1 | 15
Atrial septal defect 6 1 | 1
Attention deficit hyperactivity disorder 1 | 156
Autosomal recessive non-syndromic intellectual disability 1 | 8
Blindness 1 | 84
Bullous pemphigoid 1 | 17
Cancer 1 | 2,346
Cardiovascular system disease 1 | 194
Cataract 1 | 104
Cicatricial pemphigoid 1 | 5
Colorectal Neoplasms 1 | 217
Dental enamel hypoplasia 1 | 12
Dentinogenesis imperfecta 1 | 24
Ellis-Van Creveld syndrome 1 | 19
Epidermolysis bullosa dystrophica, Bart type 1 | 1
Epidermolysis bullosa dystrophica, Hallopeau-Siemens type 1 | 1
Epidermolysis bullosa dystrophica, Pasini type 1 | 1
Epidermolysis bullosa dystrophica, autosomal dominant 1 | 1
Epidermolysis bullosa dystrophica, autosomal recessive 1 | 1
Epidermolysis bullosa dystrophica, pretibial type 1 | 1
Epidermolysis bullosa pruriginosa 1 | 1
Generalized atrophic benign epidermolysis bullosa 1 | 3
Glaucoma 1 | 135
Hallopeau-Siemens Disease 1 | 2
Kindler syndrome 1 | 10
Laryngoonychocutaneous syndrome 1 | 1
Lupus Erythematosus, Systemic 1 | 73
Mammary Neoplasms 1 | 410
Myopia 1 | 99
Nail Diseases 1 | 3
Neurotic excoriation 1 | 2
OSTEOGENESIS IMPERFECTA, TYPE XIII 1 | 1
Osteogenesis Imperfecta, Type 13 1 | 1
Osteogenesis imperfecta 13 1 | 1
Osteogenesis imperfecta type III (disorder) 1 | 11
Ostium primum atrial septal defect 1 | 1
Ostium secundum atrial septal defect 1 | 8
Patent ductus arteriosus 1 | 23
Skin Ulcer 1 | 4
Transient bullous dermolysis of the newborn 1 | 1
Trichorhinophalangeal syndrome type II 1 | 14
Umbilical hernia 1 | 18
Vitreous detachment 1 | 9
active Crohn's disease 1 | 918
astrocytic glioma 1 | 2,241
chronic kidney disease 1 | 90
cutaneous lupus erythematosus 1 | 1,056
cystic fibrosis 1 | 1,670
inflammatory breast cancer 1 | 404
medulloblastoma 1 | 1,524
non diabetic and post-ischemic heart failure 1 | 200
oligodendroglioma 1 | 2,849
osteogenesis imperfecta type 3 1 | 11
pilocytic astrocytoma 1 | 3,086
post-traumatic stress disorder 1 | 45
posterior fossa group A ependymoma 1 | 1,511
systemic lupus erythematosus 1 | 172
tuberculosis 1 | 1,563
ulcerative colitis 1 | 2,087

Tissue

Blood and immune system 7 | 17,994
Cardiovascular System 7 | 17,957
Digestive Tract 7 | 18,472
Endocrine System 7 | 18,511
Female tissues 7 | 18,646
Liver and Pancreas 7 | 18,135
Male tissues 7 | 17,968
Nervous System 7 | 18,560
Respiratory system 7 | 17,483
Skin and soft tissues 7 | 18,114
Urinary Tract 7 | 18,443

Target Family

Non-IDG 7 | 11,969

Reactome Pathway

Anchoring fibril formation 7 | 7
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Collagen alpha-1(VII) chain COL7A1 Tbio Non-IDG -2.55582 363.5 81
Tolloid-like protein 1 TLL1 Tbio Non-IDG -1.40917 23.4 60
Bone morphogenetic protein 1 BMP1 Tchem Non-IDG -2.34268 220.1 155
Laminin subunit alpha-3 LAMA3 Tchem Non-IDG -2.52531 330.0 103
Tolloid-like protein 2 TLL2 Tdark Non-IDG -0.95989 5.61 29
Laminin subunit gamma-2 LAMC2 Tbio Non-IDG -2.05137 104.8 153
Laminin subunit beta-3 LAMB3 Tbio Non-IDG -2.05445 111.5 149