Development Level

Tbio 51 | 11,445
Tdark 7 | 6,588
Tchem 6 | 1,598
Tclin 1 | 613

IMPC Phenotype

embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal vibrissa morphology 1 | 25
brachydactyly 1 | 19
decreased circulating bilirubi... 1 | 19
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
hydrometra 1 | 53
increased blood urea nitrogen ... 1 | 48
increased fasted circulating g... 1 | 76
increased or absent threshold ... 1 | 101
limb grasping 1 | 41
male infertility 1 | 123
premature death 1 | 5
preweaning lethality, complete... 1 | 979
prolonged PR interval 1 | 15

Disease

psoriasis 33 | 6,694
Carcinoma 30 | 11,493
ovarian cancer 30 | 8,520
Cancer 25 | 2,499
lung cancer 25 | 4,740
Breast cancer 21 | 3,578
osteosarcoma 21 | 7,950
glioblastoma 18 | 5,792
pancreatic cancer 18 | 2,398
invasive ductal carcinoma 16 | 2,951
Amyloidosis 15 | 67
medulloblastoma, large-cell 15 | 6,241
Alzheimer's disease 14 | 658
atypical teratoid / rhabdoid tumor 14 | 5,112
ependymoma 14 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
lung adenocarcinoma 14 | 2,716
malignant mesothelioma 14 | 3,232
Schizophrenia 13 | 1,160
group 3 medulloblastoma 13 | 4,104
Kidney disease 12 | 430
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
lung carcinoma 12 | 2,843
non-small cell lung cancer 12 | 2,890
diabetes mellitus 11 | 1,728
ductal carcinoma in situ 11 | 1,745
Astrocytoma, Pilocytic 10 | 3,081
Hypertension 10 | 396
breast carcinoma 10 | 1,638
Dementia 9 | 175
Hypertensive disease 9 | 292
Arthritis 8 | 290
adult high grade glioma 8 | 3,801
cystic fibrosis 8 | 1,696
interstitial cystitis 8 | 2,312
primitive neuroectodermal tumor 8 | 3,035
Anemia 7 | 365
Osteoporosis 7 | 363
colon cancer 7 | 1,478
dermatomyositis 7 | 966
oligodendroglioma 7 | 2,850
pituitary cancer 7 | 1,972
primary pancreatic ductal adenocarcinoma 7 | 1,109
tuberculosis 7 | 2,010
Atherosclerosis 6 | 291
Bipolar Disorder 6 | 666
Cerebrovascular disease 6 | 238
Chemical and Drug Induced Liver Injury 6 | 195
Diarrhea 6 | 253
Edema 6 | 81
Endometriosis 6 | 540
Generalized amyloid deposition 6 | 6
Heart disease 6 | 306
Kidney Diseases 6 | 114
Multiple myeloma 6 | 1,332
Neurodegenerative disease 6 | 414
Obesity 6 | 678
active ulcerative colitis 6 | 764
astrocytic glioma 6 | 2,597
cutaneous lupus erythematosus 6 | 1,057
pancreatic carcinoma 6 | 562
subependymal giant cell astrocytoma 6 | 2,287
Alzheimer Disease 5 | 83
Cholestasis 5 | 155
Cleft Palate 5 | 271
Coronary artery disease 5 | 268
Down syndrome 5 | 499
Epilepsy 5 | 792
Hyperparathyroidism 5 | 48
Hyperthyroidism 5 | 53
Hypothyroidism 5 | 122
Intellectual disability 5 | 1,016
Kidney cancer 5 | 2,613
Liver Cirrhosis, Experimental 5 | 769
Liver disease 5 | 237
Nephrotic Syndrome 5 | 78
Neuropathy 5 | 261
Polycystic ovary syndrome 5 | 360
Splenomegaly 5 | 190
active Crohn's disease 5 | 922
group 4 medulloblastoma 5 | 1,855
juvenile dermatomyositis 5 | 1,187
non-small cell lung carcinoma 5 | 317
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Adenoma 4 | 167
Cushing's syndrome 4 | 48
Depressive disorder 4 | 409
Duchenne muscular dystrophy 4 | 601
Hepatomegaly 4 | 285
Melanoma 4 | 711
Pick disease 4 | 1,894
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
Toxic encephalopathy 4 | 141
Waldenstrons macroglobulinemia 4 | 765
astrocytoma 4 | 1,146
esophageal adenocarcinoma 4 | 737
gastric cancer 4 | 459
ulcerative colitis 4 | 1,819

Tissue

Endocrine System 63 | 18,159
Digestive Tract 62 | 17,369
Blood and immune system 61 | 16,909
Female tissues 61 | 17,400
Liver and Pancreas 61 | 16,750
Skin and soft tissues 61 | 17,230
Urinary Tract 60 | 16,678
Male tissues 59 | 17,142
Respiratory system 57 | 16,393
Nervous System 56 | 16,725
Cardiovascular System 55 | 15,192

Target Family

Non-IDG 56 | 12,091
Enzyme 9 | 4,145

Reactome Pathway

Amyloid fiber formation 65 | 65
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
Histone H2B type 1-N HIST1H2BN Tbio Non-IDG -1.51422 30.2 60
Histone H2B type 1-L HIST1H2BL Tdark Non-IDG 0.35 0.40 48
Histone H2B type 1-M HIST1H2BM Tdark Non-IDG 0.17 0.33 21
Histone H2A type 1-J HIST1H2AJ Tdark Non-IDG -0.13212 1.19 16
Cystatin-C CST3 Tbio Non-IDG -3.52815 3278.8 866
N-acetyltransferase 8 NAT8 Tbio Enzyme -1.74418 54.5 143
Histone H2A type 1-B/E HIST1H2AB Tbio Non-IDG -1.27041 18.5 133
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143