Development Level

Tbio 41 | 10,625
Tchem 7 | 1,890
Tdark 3 | 7,003

IMPC Phenotype

preweaning lethality, incomple... 2 | 260
abnormal coping response 1 | 12
abnormal epididymis morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal vitreous body morphol... 1 | 7
decreased CD4-positive, CD25-p... 1 | 24
decreased mean corpuscular vol... 1 | 50
decreased total body fat amoun... 1 | 186
enlarged epididymis 1 | 27
improved glucose tolerance 1 | 56
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased mean corpuscular hem... 1 | 93
persistence of hyaloid vascula... 1 | 22
straub tail 1 | 26

Disease

osteosarcoma 22 | 7,933
medulloblastoma, large-cell 20 | 6,234
ovarian cancer 20 | 8,491
psoriasis 19 | 6,685
atypical teratoid / rhabdoid tumor 18 | 4,369
glioblastoma 18 | 5,572
lung carcinoma 14 | 2,844
pilocytic astrocytoma 14 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,956
lung cancer 13 | 4,473
oligodendroglioma 13 | 2,849
invasive ductal carcinoma 12 | 2,950
malignant mesothelioma 12 | 3,163
pancreatic cancer 12 | 2,300
pediatric high grade glioma 12 | 2,712
ependymoma 11 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
primitive neuroectodermal tumor 11 | 3,031
non-small cell lung cancer 10 | 2,798
pituitary cancer 10 | 1,972
ulcerative colitis 10 | 2,087
Breast cancer 9 | 3,098
Cancer 9 | 2,346
Lysinuric protein intolerance 9 | 15
cystic fibrosis 9 | 1,670
group 4 medulloblastoma 9 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
subependymal giant cell astrocytoma 9 | 2,287
tuberculosis 9 | 1,563
Cystinuria 8 | 18
Epilepsy 8 | 346
atypical teratoid/rhabdoid tumor 8 | 1,095
colon cancer 8 | 1,475
ductal carcinoma in situ 8 | 1,745
interstitial cystitis 8 | 2,299
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
Hartnup disease 7 | 13
Pick disease 7 | 1,893
posterior fossa group B ependymoma 7 | 1,530
primary pancreatic ductal adenocarcinoma 7 | 1,271
Schizophrenia 6 | 503
active Crohn's disease 6 | 918
astrocytic glioma 6 | 2,241
lung adenocarcinoma 6 | 2,714
sonic hedgehog group medulloblastoma 6 | 1,482
Amyotrophic Lateral Sclerosis 5 | 432
Atopic dermatitis 5 | 944
adult high grade glioma 5 | 2,148
astrocytoma 5 | 1,493
breast carcinoma 5 | 1,614
cutaneous lupus erythematosus 5 | 1,056
group 3 medulloblastoma 5 | 2,254
posterior fossa group A ependymoma 5 | 1,511
IGA Glomerulonephritis 4 | 454
Iminoglycinuria 4 | 4
gastric carcinoma 4 | 832
nephrosclerosis 4 | 329
non primary Sjogren syndrome sicca 4 | 840
Allan-Herndon-Dudley syndrome 3 | 11
Barrett's esophagus 3 | 185
Carcinoma 3 | 2,147
Duchenne muscular dystrophy 3 | 602
Endometriosis 3 | 535
HYPERGLYCINURIA (disorder) 3 | 3
Hyperglycinuria 3 | 3
Melanoma 3 | 261
Multiple myeloma 3 | 1,327
Parkinson's disease 3 | 364
Polycystic Ovary Syndrome 3 | 334
Rheumatoid Arthritis 3 | 1,170
Toxic encephalopathy 3 | 131
active ulcerative colitis 3 | 477
acute quadriplegic myopathy 3 | 1,157
adrenocortical carcinoma 3 | 1,427
diabetes mellitus 3 | 1,663
facioscapulohumeral dystrophy 3 | 286
juvenile dermatomyositis 3 | 1,189
medulloblastoma 3 | 1,524
nasopharyngeal carcinoma 3 | 1,056
spina bifida 3 | 1,064
uncontrolled asthma 3 | 67
Alzheimer's disease 2 | 644
Down syndrome 2 | 548
Glaucoma 2 | 135
Nephrolithiasis 2 | 31
Neurodegenerative disease 2 | 383
Pellagra 2 | 25
Prostatic Neoplasms 2 | 471
Seizures 2 | 95
Vascular disease 2 | 281
X-linked cerebral adrenoleukodystrophy 2 | 115
aldosterone-producing adenoma 2 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
fibroadenoma 2 | 557
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
mucosa-associated lymphoid tissue lymphoma 2 | 480
non diabetic and post-ischemic heart failure 2 | 200
primary Sjogren syndrome 2 | 788
progressive supranuclear palsy 2 | 674
systemic lupus erythematosus 2 | 172

Tissue

Digestive Tract 50 | 18,472
Endocrine System 50 | 18,511
Female tissues 50 | 18,646
Liver and Pancreas 50 | 18,135
Nervous System 50 | 18,560
Skin and soft tissues 50 | 18,114
Male tissues 49 | 17,968
Urinary Tract 49 | 18,443
Blood and immune system 48 | 17,994
Cardiovascular System 48 | 17,957
Respiratory system 48 | 17,483

Target Family

Transporter 51 | 473

Reactome Pathway

Amino acid and oligopeptide SL... 51 | 51
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.84839 135.6 220
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 Tbio Transporter -1.37527 22.6 67
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -1.98538 103.1 38
Y+L amino acid transporter 1 SLC7A7 Tbio Transporter -1.71025 51.9 32
Cationic amino acid transporter 2 SLC7A2 Tbio Transporter -1.51303 33.6 47
Sodium- and chloride-dependent taurine transporter SLC6A6 Tchem Transporter -2.45345 270.0 85
Sodium-coupled monocarboxylate transporter 1 SLC5A8 Tbio Transporter -1.87440 72.7 92
Solute carrier family 15 member 4 SLC15A4 Tbio Transporter -1.80561 84.5 40
Sialin SLC17A5 Tbio Transporter -2.90917 800.3 60
Neutral amino acid transporter B(0) SLC1A5 Tbio Transporter -2.55051 323.7 122