Development Level

Tbio 41 | 10,625
Tchem 7 | 1,890
Tdark 3 | 7,003

IMPC Term

preweaning lethality, incomple... 2 | 260
abnormal coping response 1 | 12
abnormal epididymis morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal vitreous body morphol... 1 | 7
decreased CD4-positive, CD25-p... 1 | 24
decreased mean corpuscular vol... 1 | 50
decreased total body fat amoun... 1 | 186
enlarged epididymis 1 | 27
improved glucose tolerance 1 | 56
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased mean corpuscular hem... 1 | 93
persistence of hyaloid vascula... 1 | 22
straub tail 1 | 26

Disease

osteosarcoma 22 | 7,933
medulloblastoma, large-cell 20 | 6,234
ovarian cancer 20 | 8,492
psoriasis 19 | 6,685
atypical teratoid / rhabdoid tumor 18 | 4,369
glioblastoma 18 | 5,572
lung carcinoma 14 | 2,844
pilocytic astrocytoma 14 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,956
lung cancer 13 | 4,473
oligodendroglioma 13 | 2,849
invasive ductal carcinoma 12 | 2,950
malignant mesothelioma 12 | 3,163
pancreatic cancer 12 | 2,300
pediatric high grade glioma 12 | 2,712
ependymoma 11 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
primitive neuroectodermal tumor 11 | 3,031
non-small cell lung cancer 10 | 2,798
pituitary cancer 10 | 1,972
ulcerative colitis 10 | 2,087
Breast cancer 9 | 3,099
Cancer 9 | 2,346
Lysinuric protein intolerance 9 | 15
cystic fibrosis 9 | 1,670
group 4 medulloblastoma 9 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
subependymal giant cell astrocytoma 9 | 2,287
tuberculosis 9 | 1,563
Cystinuria 8 | 18
Epilepsy 8 | 346
atypical teratoid/rhabdoid tumor 8 | 1,095
colon cancer 8 | 1,475
ductal carcinoma in situ 8 | 1,745
interstitial cystitis 8 | 2,299
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
Hartnup disease 7 | 13
Pick disease 7 | 1,893
posterior fossa group B ependymoma 7 | 1,530
primary pancreatic ductal adenocarcinoma 7 | 1,271
Schizophrenia 6 | 503
active Crohn's disease 6 | 918
astrocytic glioma 6 | 2,241
lung adenocarcinoma 6 | 2,714
sonic hedgehog group medulloblastoma 6 | 1,482
Amyotrophic Lateral Sclerosis 5 | 432
Atopic dermatitis 5 | 944
adult high grade glioma 5 | 2,148
astrocytoma 5 | 1,493
breast carcinoma 5 | 1,614
cutaneous lupus erythematosus 5 | 1,056
group 3 medulloblastoma 5 | 2,254
posterior fossa group A ependymoma 5 | 1,511
IGA Glomerulonephritis 4 | 454
Iminoglycinuria 4 | 4
gastric carcinoma 4 | 832
nephrosclerosis 4 | 329
non primary Sjogren syndrome sicca 4 | 840
Allan-Herndon-Dudley syndrome 3 | 11
Barrett's esophagus 3 | 185
Carcinoma 3 | 2,147
Duchenne muscular dystrophy 3 | 602
Endometriosis 3 | 535
HYPERGLYCINURIA (disorder) 3 | 3
Hyperglycinuria 3 | 3
Melanoma 3 | 261
Multiple myeloma 3 | 1,328
Parkinson's disease 3 | 364
Polycystic Ovary Syndrome 3 | 335
Rheumatoid Arthritis 3 | 1,171
Toxic encephalopathy 3 | 131
active ulcerative colitis 3 | 477
acute quadriplegic myopathy 3 | 1,157
adrenocortical carcinoma 3 | 1,427
diabetes mellitus 3 | 1,663
facioscapulohumeral dystrophy 3 | 286
juvenile dermatomyositis 3 | 1,189
medulloblastoma 3 | 1,524
nasopharyngeal carcinoma 3 | 1,056
spina bifida 3 | 1,064
uncontrolled asthma 3 | 67
Alzheimer's disease 2 | 644
Down syndrome 2 | 548
Glaucoma 2 | 135
Nephrolithiasis 2 | 31
Neurodegenerative disease 2 | 383
Pellagra 2 | 25
Prostatic Neoplasms 2 | 471
Seizures 2 | 95
Vascular disease 2 | 281
X-linked cerebral adrenoleukodystrophy 2 | 115
aldosterone-producing adenoma 2 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
fibroadenoma 2 | 557
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
mucosa-associated lymphoid tissue lymphoma 2 | 480
non diabetic and post-ischemic heart failure 2 | 200
primary Sjogren syndrome 2 | 789
progressive supranuclear palsy 2 | 674
systemic lupus erythematosus 2 | 172

Tissue

Digestive Tract 50 | 18,473
Endocrine System 50 | 18,512
Female tissues 50 | 18,647
Liver and Pancreas 50 | 18,136
Nervous System 50 | 18,561
Skin and soft tissues 50 | 18,115
Male tissues 49 | 17,969
Urinary Tract 49 | 18,444
Blood and immune system 48 | 17,995
Cardiovascular System 48 | 17,958
Respiratory system 48 | 17,484

Target Family

Transporter 51 | 473

Reactome Pathway

Amino acid and oligopeptide SL... 51 | 51
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium-coupled neutral amino acid transporter 5 SLC38A5 Tbio Transporter -3.02540 1028.1 61
Large neutral amino acids transporter small subunit 2 SLC7A8 Tbio Transporter -1.14964 15.8 88
Sodium-coupled neutral amino acid transporter 3 SLC38A3 Tbio Transporter 0.00000 46
Sodium-dependent phosphate transport protein 1 SLC17A1 Tbio Transporter -1.72792 42.9 28
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.84839 135.6 220
High affinity cationic amino acid transporter 1 SLC7A1 Tbio Transporter -2.68661 466.7 136
Cationic amino acid transporter 3 SLC7A3 Tbio Transporter -2.17447 140.1 25
Sodium-coupled neutral amino acid transporter 2 SLC38A2 Tbio Transporter -1.93885 83.9 78
Proton-coupled amino acid transporter 2 SLC36A2 Tbio Transporter -1.77546 59.0 73
Sodium- and chloride-dependent betaine transporter SLC6A12 Tchem Transporter -2.32183 191.9 86