Development Level

Tbio 9 | 10,625
Tdark 5 | 7,003
Tchem 3 | 1,890
Tclin 3 | 602

IMPC Phenotype

decreased mean corpuscular vol... 1 | 50
increased mean corpuscular vol... 1 | 91

Disease

osteosarcoma 8 | 7,933
ovarian cancer 8 | 8,491
lung carcinoma 7 | 2,844
psoriasis 7 | 6,685
Cancer 6 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
medulloblastoma, large-cell 5 | 6,234
tuberculosis 5 | 1,563
Hypertension 4 | 293
Liver disease 4 | 219
interstitial cystitis 4 | 2,299
lung cancer 4 | 4,473
pancreatic cancer 4 | 2,300
primary pancreatic ductal adenocarcinoma 4 | 1,271
Cholestasis 3 | 93
Hepatitis C 3 | 90
Kidney disease 3 | 397
Prostatic Neoplasms 3 | 471
adrenocortical carcinoma 3 | 1,427
atypical teratoid / rhabdoid tumor 3 | 4,369
diabetes mellitus 3 | 1,663
glioblastoma 3 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
lung adenocarcinoma 3 | 2,714
malignant mesothelioma 3 | 3,163
Alcohol dependence 2 | 107
Atherosclerosis 2 | 275
Bilirubin metabolic disorder 2 | 39
Breast cancer 2 | 3,098
Cardiovascular system disease 2 | 194
Cholangitis 2 | 20
Choledocholithiasis 2 | 13
Coronary artery disease 2 | 240
Fatty liver disease 2 | 86
Hepatitis B 2 | 103
Human immunodeficiency virus infection 2 | 6
Liver diseases 2 | 66
Metabolic syndrome X 2 | 155
Obesity 2 | 616
Progeria 2 | 22
Schizophrenia 2 | 503
Substance abuse 2 | 55
adult high grade glioma 2 | 2,148
astrocytic glioma 2 | 2,241
breast carcinoma 2 | 1,614
cutaneous lupus erythematosus 2 | 1,056
ependymoma 2 | 2,514
group 4 medulloblastoma 2 | 1,875
non primary Sjogren syndrome sicca 2 | 840
non-small cell lung cancer 2 | 2,798
oligodendroglioma 2 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
periodontitis 2 | 269
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 1,530
spina bifida 2 | 1,064
Adenocarcinoma of lung (disorder) 1 | 48
Adverse reaction to drug 1 | 54
Alcoholic Intoxication, Chronic 1 | 41
Animal Mammary Neoplasms 1 | 135
Atrophic 1 | 10
Autoimmune hepatitis 1 | 13
Barrett's esophagus 1 | 185
Brucellosis 1 | 24
Choroid Plexus Papilloma 1 | 10
Chronic Obstructive Airway Disease 1 | 47
Colorectal Neoplasms 1 | 217
Common variable immunodeficiency 1 | 98
Contagious pustular dermatitis 1 | 12
Diarrhea 1 | 155
Exanthem 1 | 39
Growth Disorders 1 | 33
Human immunodeficiency virus infectious disease 1 | 129
Kidney Diseases 1 | 86
Leber congenital amaurosis 1 | 72
Liver Cirrhosis, Experimental 1 | 108
Liver Neoplasms, Experimental 1 | 48
Lung Injury 1 | 20
Lung Neoplasms 1 | 171
Mammary Neoplasms 1 | 410
Mammary Neoplasms, Experimental 1 | 149
Melanoma 1 | 261
Meningitis 1 | 46
Myocardial Infarction 1 | 126
Neoplastic Cell Transformation 1 | 81
Neural Tube Defects 1 | 31
Neutropenia 1 | 78
Pain agnosia 1 | 99
Pancreatitis 1 | 97
Precancerous Conditions 1 | 69
Pyelonephritis 1 | 12
Renal Cell Carcinoma 1 | 199
Squamous cell carcinoma 1 | 96
Succinic semialdehyde dehydrogenase deficiency 1 | 16
active ulcerative colitis 1 | 477
fascioscapulohumeral muscular dystrophy 1 | 100
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
hereditary spastic paraplegia 1 | 313
sarcoidosis 1 | 368

Tissue

Digestive Tract 19 | 18,472
Endocrine System 19 | 18,511
Female tissues 19 | 18,646
Liver and Pancreas 19 | 18,135
Male tissues 19 | 17,968
Nervous System 19 | 18,560
Respiratory system 19 | 17,483
Skin and soft tissues 19 | 18,114
Urinary Tract 19 | 18,443
Blood and immune system 18 | 17,994
Cardiovascular System 18 | 17,957

Target Family

Enzyme 18 | 4,146
Non-IDG 2 | 11,969

Reactome Pathway

Aflatoxin activation and detox... 20 | 20
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aflatoxin B1 aldehyde reductase member 2 AKR7A2 Tbio Enzyme -2.54957 354.9 158
Cytochrome P450 1A2 CYP1A2 Tchem Non-IDG -3.31421 2022.5 420
Cytochrome P450 3A5 CYP3A5 Tclin Enzyme -2.80197 609.8 100
Dipeptidase 3 DPEP3 Tdark Enzyme -0.73860 4.89 74
Dipeptidase 2 DPEP2 Tdark Enzyme -0.86722 6.28 32
Aflatoxin B1 aldehyde reductase member 4 AKR7L Tdark Enzyme -0.98768 15.0 0
Microsomal glutathione S-transferase 3 MGST3 Tchem Enzyme -1.38561 24.6 57
Aminoacylase-1 ACY1 Tbio Enzyme -2.00158 99.7 257
Gamma-glutamyltransferase 5 GGT5 Tbio Enzyme -1.87678 73.9 68
Gamma-glutamyltransferase 6 GGT6 Tdark Enzyme -0.29857 2.02 94