Development Level

Tclin 2 | 613

Disease

Acute exacerbation of asthma 2 | 14
Administration of Local Anesthetic Nerve Block 2 | 14
Allergic Reactions 2 | 7
Asthma management 2 | 19
Attention deficit hyperactivity disorder 2 | 278
Bronchiectasis 2 | 64
Bronchitis 2 | 43
Cerebral Ischemia 2 | 37
Cerebrovascular Occlusion 2 | 5
Cerebrovascular disease 2 | 238
Conscious sedation 2 | 10
Dermal Necrosis 2 | 6
Diagnostic Test for Pheochromocytoma 2 | 6
Disorder of blood vessel 2 | 4
Dyspnea 2 | 76
Exacerbation of asthma 2 | 11
Hypertension Secondary to Pheochromocytoma 2 | 6
Hypertensive Emergencies 2 | 10
Hypertensive disorder 2 | 56
Increased Intraocular Pressure after Ocular Procedure 2 | 3
Local anesthesia, by infiltration 2 | 14
Low blood pressure 2 | 9
Muscle Spasticity of Cerebral Origin 2 | 8
Muscle spasticity of spinal origin 2 | 8
Nasal congestion 2 | 21
Nasal discharge 2 | 24
Ocular Itching 2 | 4
Ocular hypertension 2 | 42
Open-angle glaucoma 2 | 27
Orthostatic hypotension 2 | 9
Parkinson's disease 2 | 392
Paroxysmal hypertension 2 | 6
Percutaneous coronary intervention 2 | 9
Peripheral vascular disease 2 | 87
Persistent pulmonary hypertension of the newborn 2 | 8
Pheochromocytoma 2 | 24
Prevention of Cerebral Thrombosis 2 | 29
Prevention of Hypertension in Pheochromocytoma 2 | 6
Pulmonary emphysema 2 | 48
Red eye 2 | 7
Rosacea 2 | 25
Severe pain 2 | 11
Spasticity 2 | 26
Subacute Stent Thrombosis Prevention 2 | 5
Wheezing 2 | 7
anaphylaxis 2 | 11
psoriasis 2 | 6,694
Adult onset 1 | 82
Asthma 1 | 385
Benign adult familial myoclonic epilepsy 1 | 2
Bipolar Disorder 1 | 666
Blepharospasm 1 | 13
Carcinoma 1 | 11,493
Cardiomegaly 1 | 116
Coronary artery disease 1 | 268
Cyanosis 1 | 17
EEG with irregular generalized spike and wave complexes 1 | 1
EPILEPSY, FAMILIAL ADULT MYOCLONIC, 1 1 | 2
Electroencephalogram abnormal 1 | 101
Enhancement of the C-reflex 1 | 1
Epilepsy 1 | 792
Epilepsy, Familial Adult Myoclonic, 2 1 | 1
Epilepsy, Myoclonic, Benign Adult Familial, Type 2 1 | 1
Fibrosis 1 | 44
Generalized seizures 1 | 9
Generalized seizures, recurrent 1 | 9
Giant somatosensory evoked potentials (SEPs) 1 | 1
Gilles de la Tourette syndrome 1 | 47
Heart failure 1 | 162
Hypertension 1 | 396
Intellectual disability 1 | 1,016
Jerk-locked premyoclonus spikes 1 | 1
Local anesthesia 1 | 40
Lung diseases 1 | 50
Mood Disorders 1 | 184
Myoclonus 1 | 74
Nonprogressive 1 | 12
Pain agnosia 1 | 104
Persistent erythema of skin 1 | 2
Photoparoxysmal response on EEG 1 | 1
Seizures, Focal 1 | 14
Tonic - clonic seizures 1 | 44
Tremor 1 | 113
Tremor of hands 1 | 3
adult high grade glioma 1 | 3,801
astrocytoma 1 | 1,146
breast carcinoma 1 | 1,638
fibroadenoma 1 | 559
glioblastoma 1 | 5,792
lung adenocarcinoma 1 | 2,716
lung cancer 1 | 4,740
malignant mesothelioma 1 | 3,232
non primary Sjogren syndrome sicca 1 | 891
ovarian cancer 1 | 8,520
primitive neuroectodermal tumor 1 | 3,035

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

GPCR 2 | 408

Reactome Pathway

Adrenaline signalling through ... 2 | 2
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-2B adrenergic receptor ADRA2B Tclin GPCR -2.15839 139.8 0
Alpha-2C adrenergic receptor ADRA2C Tclin GPCR -1.97108 93.5 343