Development Level

Tchem 8 | 1,598
Tbio 6 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

cataract 2 | 92
abnormal lens morphology 1 | 81
decreased leukocyte cell numbe... 1 | 73
increased body weight 1 | 25
increased circulating sodium l... 1 | 71
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 9 | 8,520
psoriasis 9 | 6,694
Carcinoma 7 | 11,493
lung cancer 7 | 4,740
osteosarcoma 7 | 7,950
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
pancreatic cancer 6 | 2,398
active Crohn's disease 5 | 922
glioblastoma 5 | 5,792
lung carcinoma 5 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Toxic encephalopathy 4 | 141
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
medulloblastoma, large-cell 4 | 6,241
non-small cell lung cancer 4 | 2,890
pituitary cancer 4 | 1,972
Arthritis 3 | 290
Astrocytoma, Pilocytic 3 | 3,081
Atherosclerosis 3 | 291
Bipolar Disorder 3 | 666
Breast cancer 3 | 3,578
Coronary artery disease 3 | 268
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
group 3 medulloblastoma 3 | 4,104
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Acute pancreatitis 2 | 10
Cancer 2 | 2,499
Gas gangrene 2 | 17
Liver Cirrhosis, Experimental 2 | 769
MAJOR AFFECTIVE DISORDER 2 2 | 22
Membranous glomerulonephritis 2 | 13
Nephrotic Syndrome 2 | 78
Pick disease 2 | 1,894
Proteinuria 2 | 144
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
malignant mesothelioma 2 | 3,232
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
ulcerative colitis 2 | 1,819
Acute chest syndrome 1 | 9
Amyotrophic lateral sclerosis 1 | 451
Autistic Disorder 1 | 364
Barrett's esophagus 1 | 182
Bladder Diverticulum 1 | 15
Breast Neoplasms 1 | 445
Carcinoma of colon 1 | 32
Cerebrovascular disease 1 | 238
Colorectal Neoplasms 1 | 243
Depressive disorder 1 | 409
Dermatitis 1 | 157
Duchenne muscular dystrophy 1 | 601
Endometriosis 1 | 540
Epilepsy 1 | 792
Eye disease 1 | 62
IGA Glomerulonephritis 1 | 50
Kidney disease 1 | 430
Liver cancer 1 | 604
Lupus nephritis 1 | 13
Mammary Neoplasms 1 | 425
Mood Disorders 1 | 184
Myocardial Ischemia 1 | 169
Osteoarthritis 1 | 184
Reperfusion Injury 1 | 86
Schizoaffective Disorder 1 | 55
Skin cancer 1 | 469
Splenic marginal zone lymphoma 1 | 7
Substance-Related Disorders 1 | 115
Thyroid cancer 1 | 36
Weight Gain 1 | 100
acute quadriplegic myopathy 1 | 1,158
adrenocortical adenoma 1 | 131
colon cancer 1 | 1,478
glioblastoma multiforme 1 | 142
head and neck cancer 1 | 271
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
hepatocellular carcinoma 1 | 547
inflammatory breast cancer 1 | 286
limb girdle muscular dystrophy 2A 1 | 213
nasopharyngeal carcinoma 1 | 1,058
non diabetic and post-ischemic heart failure 1 | 200
non-small cell lung carcinoma 1 | 317
tuberculosis and treatment for 3 months 1 | 179
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Female tissues 15 | 17,400
Male tissues 15 | 17,142
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Endocrine System 14 | 18,159
Liver and Pancreas 13 | 16,750
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Cardiovascular System 11 | 15,192

Target Family

Enzyme 16 | 4,145

Reactome Pathway

Acyl chain remodelling of PG 16 | 16
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Group IIE secretory phospholipase A2 PLA2G2E Tchem Enzyme -0.44734 2.04 30
Cytosolic phospholipase A2 delta PLA2G4D Tbio Enzyme -0.54284 3.41 45
Phospholipase A2, membrane associated PLA2G2A Tchem Enzyme -2.83666 743.3 137
Group IIF secretory phospholipase A2 PLA2G2F Tchem Enzyme -0.17609 1.39 2
Calcium-dependent phospholipase A2 PLA2G5 Tchem Enzyme -1.38065 26.2 137
Cytosolic phospholipase A2 PLA2G4A Tchem Enzyme -2.68316 506.7 274
Cytosolic phospholipase A2 zeta PLA2G4F Tdark Enzyme 0.59 0.40 38
Group 3 secretory phospholipase A2 PLA2G3 Tbio Enzyme -0.91137 8.37 128
Group IID secretory phospholipase A2 PLA2G2D Tchem Enzyme -2.16892 139.3 119
Group 10 secretory phospholipase A2 PLA2G10 Tchem Enzyme -2.41226 298.2 57