Development Level

Tbio 10 | 11,445
Tchem 10 | 1,598
Tdark 5 | 6,588

IMPC Phenotype

cataract 2 | 92
abnormal lens morphology 1 | 81
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
increased body weight 1 | 25
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 14 | 11,493
osteosarcoma 12 | 7,950
ovarian cancer 12 | 8,520
psoriasis 12 | 6,694
lung cancer 8 | 4,740
pancreatic cancer 8 | 2,398
atypical teratoid / rhabdoid tumor 7 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung adenocarcinoma 7 | 2,716
lung carcinoma 7 | 2,843
medulloblastoma, large-cell 7 | 6,241
Breast cancer 6 | 3,578
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
non-small cell lung cancer 6 | 2,890
Schizophrenia 5 | 1,160
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
Astrocytoma, Pilocytic 4 | 3,081
Bipolar Disorder 4 | 666
Toxic encephalopathy 4 | 141
active Crohn's disease 4 | 922
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
group 3 medulloblastoma 4 | 4,104
primitive neuroectodermal tumor 4 | 3,035
Arthritis 3 | 290
Atherosclerosis 3 | 291
Coronary artery disease 3 | 268
Kidney cancer 3 | 2,613
adrenocortical carcinoma 3 | 1,428
cystic fibrosis 3 | 1,696
nasopharyngeal carcinoma 3 | 1,058
oligodendroglioma 3 | 2,850
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Acute pancreatitis 2 | 10
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Cerebellar Dysmetria 2 | 56
Depressive disorder 2 | 409
Dysarthria 2 | 192
Dystonia 2 | 164
Dystonic disease 2 | 106
Epilepsy 2 | 792
Gas gangrene 2 | 17
Ileocolitis 2 | 5
Infantile onset 2 | 238
Liver Cirrhosis, Experimental 2 | 769
MAJOR AFFECTIVE DISORDER 2 2 | 22
Membranous glomerulonephritis 2 | 13
Muscle Spasticity 2 | 195
Muscle hypotonia 2 | 571
Nephrotic Syndrome 2 | 78
Neurodegeneration with brain iron accumulation 2 | 20
Neutral lipid storage disease 2 | 12
Pick disease 2 | 1,894
Progressive disorder 2 | 142
Proteinuria 2 | 144
acute quadriplegic myopathy 2 | 1,158
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
group 4 medulloblastoma 2 | 1,855
malignant mesothelioma 2 | 3,232
non-small cell lung carcinoma 2 | 317
pancreatic carcinoma 2 | 562
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010
Abnormal vision 1 | 52
Amblyopia 1 | 38
Bladder Diverticulum 1 | 15
Cachexia 1 | 50
Carcinoma of colon 1 | 32
Carcinoma, Non-Small-Cell Lung 1 | 107
Childhood onset 1 | 38
Complex partial seizure with impairment of consciousness 1 | 9
Complex partial seizures 1 | 9
Deglutition Disorders 1 | 132
Esotropia 1 | 31
Exotropia 1 | 35
Hyperactive behavior 1 | 91
Lupus nephritis 1 | 13
Muscle Rigidity 1 | 49
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Nevus 1 | 19
Nonorganic psychosis 1 | 84
Panic disorder 1 | 61
Parkinsonian Disorders 1 | 56
Postural instability 1 | 19
Scotoma 1 | 22
Splenic marginal zone lymphoma 1 | 7
Thyroid cancer 1 | 36

Tissue

Blood and immune system 25 | 16,909
Digestive Tract 25 | 17,369
Female tissues 24 | 17,400
Skin and soft tissues 24 | 17,230
Endocrine System 23 | 18,159
Male tissues 23 | 17,142
Urinary Tract 23 | 16,678
Respiratory system 22 | 16,393
Liver and Pancreas 21 | 16,750
Nervous System 21 | 16,725
Cardiovascular System 19 | 15,192

Target Family

Enzyme 24 | 4,145
Non-IDG 1 | 12,091

Reactome Pathway

Acyl chain remodelling of PC 25 | 25
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phospholipase A2 PLA2G1B Tchem Enzyme -3.17567 1113.8 211
Phospholipase A2, membrane associated PLA2G2A Tchem Enzyme -2.83666 743.3 137
Cytosolic phospholipase A2 PLA2G4A Tchem Enzyme -2.68316 506.7 274
85/88 kDa calcium-independent phospholipase A2 PLA2G6 Tchem Enzyme -2.50583 353.3 143
Group 10 secretory phospholipase A2 PLA2G10 Tchem Enzyme -2.41226 298.2 57
Secretory phospholipase A2 receptor PLA2R1 Tbio Enzyme -2.11543 169.5 104
Lysophospholipid acyltransferase 5 LPCAT3 Tbio Enzyme -2.21771 162.8 32
Group IID secretory phospholipase A2 PLA2G2D Tchem Enzyme -2.16892 139.3 119
HRAS-like suppressor 3 PLA2G16 Tbio Non-IDG -1.96915 96.3 230
Calcium-independent phospholipase A2-gamma PNPLA8 Tbio Enzyme -1.96549 89.5 114