Development Level

Tbio 55 | 11,445
Tchem 4 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal spleen morphology 1 | 55
embryonic lethality prior to o... 1 | 239
hemorrhage 1 | 23
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
prolonged QT interval 1 | 38

Disease

ovarian cancer 30 | 8,520
lung cancer 23 | 4,740
Multiple myeloma 20 | 1,332
medulloblastoma, large-cell 18 | 6,241
Carcinoma 17 | 11,493
diabetes mellitus 16 | 1,728
osteosarcoma 15 | 7,950
Diamond-Blackfan anemia 13 | 31
glioblastoma 13 | 5,792
atypical teratoid / rhabdoid tumor 12 | 5,112
Cancer 11 | 2,499
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
psoriasis 10 | 6,694
Anemia 9 | 365
Abnormality of the urinary system 8 | 21
Anemia, Diamond-Blackfan 8 | 16
Anemia, Macrocytic 8 | 18
Cardiac Arrhythmia 8 | 103
Cardiac conduction abnormalities 8 | 78
Cleft Palate 8 | 271
Conduction disorder of the heart 8 | 79
Delayed Puberty 8 | 97
EKG abnormalities 8 | 78
Electrocardiogram abnormal 8 | 81
Electrocardiogram change 8 | 78
Fatigue 8 | 182
Hand deformities 8 | 32
Intermittent migraine headaches 8 | 68
Migraine Disorders 8 | 76
Pallor 8 | 40
Uranostaphyloschisis 8 | 167
Waldenstrons macroglobulinemia 8 | 765
genital abnormal 8 | 17
oligodendroglioma 8 | 2,850
reproductive system abnormality 8 | 17
Breast cancer 7 | 3,578
acute quadriplegic myopathy 7 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
Breast Neoplasms 6 | 445
Mammary Neoplasms 6 | 425
astrocytoma 6 | 1,146
malignant mesothelioma 6 | 3,232
Disease Progression 5 | 136
Stomach Neoplasms 5 | 300
cystic fibrosis 5 | 1,696
pancreatic cancer 5 | 2,398
primitive neuroectodermal tumor 5 | 3,035
sonic hedgehog group medulloblastoma 5 | 467
Astrocytoma, Pilocytic 4 | 3,081
Infantile onset 4 | 238
Reticulocytopenia 4 | 10
acute myeloid leukemia 4 | 783
hereditary spastic paraplegia 4 | 318
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
mucosa-associated lymphoid tissue lymphoma 4 | 484
non-small cell lung cancer 4 | 2,890
pediatric high grade glioma 4 | 1,064
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
HIV Infections 3 | 102
Hereditary spherocytosis type 4 3 | 18
Irregular astigmatism 3 | 12
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Retinitis pigmentosa 29 3 | 6
adult high grade glioma 3 | 3,801
inflammatory breast cancer 3 | 286
juvenile dermatomyositis 3 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Acquired metabolic disease 2 | 336
Adenocarcinoma of lung 2 | 142
Amyotrophic lateral sclerosis 2 | 451
Carcinoma, Hepatocellular 2 | 228
Disease Models, Animal 2 | 155
Downward slant of palpebral fissure 2 | 158
Duchenne muscular dystrophy 2 | 601
Hypertension 2 | 396
Hypoplastic myelodysplasia 2 | 18
Hypoxia 2 | 33
Liver carcinoma 2 | 240
MYELODYSPLASTIC SYNDROME 2 | 53
Neoplasm Invasiveness 2 | 161
Polycystic ovary syndrome 2 | 360
Shwachman-Diamond syndrome 2 | 17
Thrombocytosis 2 | 38
Turner syndrome 2 | 28
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
dermatomyositis 2 | 966
fascioscapulohumeral muscular dystrophy 2 | 100
gastric carcinoma 2 | 807
glioblastoma multiforme 2 | 142
medulloblastoma 2 | 720
posterior fossa group A ependymoma 2 | 468
spina bifida 2 | 1,074
tuberculosis and treatment for 3 months 2 | 179

Tissue

Blood and immune system 59 | 16,909
Endocrine System 59 | 18,159
Male tissues 59 | 17,142
Cardiovascular System 58 | 15,192
Digestive Tract 58 | 17,369
Female tissues 58 | 17,400
Liver and Pancreas 58 | 16,750
Nervous System 58 | 16,725
Respiratory system 58 | 16,393
Skin and soft tissues 58 | 17,230
Urinary Tract 58 | 16,678

Target Family

Non-IDG 60 | 12,091

Reactome Pathway

Activation of the mRNA upon bi... 60 | 60
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Eukaryotic translation initiation factor 3 subunit C EIF3C Tbio Non-IDG -1.20680 14.1 159
Eukaryotic translation initiation factor 3 subunit B EIF3B Tbio Non-IDG -1.83618 70.5 84
40S ribosomal protein S21 RPS21 Tbio Non-IDG -1.92202 82.6 72
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.19489 157.7 218
40S ribosomal protein S30 FAU Tbio Non-IDG -2.15283 258.8 284
40S ribosomal protein S24 RPS24 Tbio Non-IDG -1.91732 77.3 92
40S ribosomal protein S26 RPS26 Tbio Non-IDG -1.58194 37.1 71
40S ribosomal protein S15 RPS15 Tbio Non-IDG -2.22249 154.8 149
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139