Development Level

Tbio 12 | 11,651
Tchem 4 | 1,388

IMPC Phenotype

abnormal cecum morphology 1 | 7
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
enlarged cecum 1 | 5
enlarged uterus 1 | 11
increased eosinophil cell numb... 1 | 11
increased neutrophil cell numb... 1 | 46
small superior vagus ganglion 1 | 74

Disease

Carcinoma 10 | 11,493
medulloblastoma, large-cell 8 | 6,241
ovarian cancer 8 | 8,520
Cancer 7 | 2,499
lung cancer 7 | 4,740
psoriasis 7 | 6,694
glioblastoma 6 | 5,792
osteosarcoma 6 | 7,950
adult high grade glioma 4 | 3,801
group 4 medulloblastoma 4 | 1,855
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
Breast cancer 3 | 3,578
Encephalitis, Herpes Simplex 3 | 4
Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere 3 | 5
HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 1 3 | 5
Herpes encephalitis 3 | 6
Influenza 3 | 142
Multiple Sclerosis 3 | 540
astrocytic glioma 3 | 2,597
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
pancreatic cancer 3 | 2,398
progressive supranuclear palsy 3 | 676
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Amyotrophic lateral sclerosis 2 | 451
Anemia 2 | 365
Astrocytoma, Pilocytic 2 | 3,081
Brain Injuries 2 | 65
Cerebrovascular disease 2 | 238
Cleft Palate 2 | 271
Colorectal Neoplasms 2 | 243
Dysarthria 2 | 192
Fatigue 2 | 182
Gastritis 2 | 47
Gaucher disease type 1 2 | 180
Hantavirus pulmonary syndrome 2 | 6
Hypoplastic mandible condyle 2 | 275
Inflammation 2 | 120
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Major Depressive Disorder 2 | 301
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Microphthalmia with limb anomalies 2 | 40
Multiple myeloma 2 | 1,332
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Neoplasm Metastasis 2 | 168
Perinatal necrotizing enterocolitis 2 | 21
Pick's disease 2 | 15
Reperfusion Injury 2 | 86
Respiratory Failure 2 | 104
Respiratory Syncytial Virus Infections 2 | 5
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Unipolar Depression 2 | 250
Uranostaphyloschisis 2 | 167
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
periodontitis 2 | 293
pituitary cancer 2 | 1,972
Acquired cubitus valgus 1 | 18
Acute coronary syndrome 1 | 39
Anomalous pulmonary artery 1 | 4
Behcet's syndrome 1 | 50
Bundle-Branch Block 1 | 8
Cardiofaciocutaneous syndrome 1 | 15
Cleft uvula 1 | 27
Diabetic Neuropathies 1 | 14
Endometritis 1 | 21
Enlarged thorax 1 | 18
Factor XII deficiency 1 | 13
LEOPARD syndrome 1 | 20
Limited elbow movement 1 | 6
Neurofibrosarcoma 1 | 7
Noonan syndrome 1 | 34
Papule 1 | 43
Pneumoconiosis 1 | 15
Postnatal growth retardation 1 | 57
Scapular weakness 1 | 23
Senile lentigo 1 | 10
Submucous cleft of hard palate 1 | 11
Substance abuse 1 | 59
Winged scapula 1 | 23

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Non-IDG 11 | 12,091
Kinase 2 | 634
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

Reactome Pathway

Activation of IRF3/IRF7 mediat... 16 | 16
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase TBK1 TBK1 Tchem Kinase -2.76728 569.1 455
TIR domain-containing adapter molecule 1 TICAM1 Tbio Non-IDG -1.50467 33.0 226
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.11032 1400.0 1077
Interferon regulatory factor 7 IRF7 Tbio Transcription Factor -2.48812 287.5 464
Toll-like receptor 4 TLR4 Tchem Non-IDG -3.81927 6905.8 1289
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
TRAF family member-associated NF-kappa-B activator TANK Tbio Non-IDG -1.81992 67.5 373
TIR domain-containing adapter molecule 2 TICAM2 Tbio Non-IDG -1.18212 14.6 258
Lymphocyte antigen 96 LY96 Tbio Non-IDG -2.77678 541.2 369