Development Level

Tbio 13 | 10,625
Tchem 5 | 1,890

Disease

ovarian cancer 10 | 8,484
medulloblastoma, large-cell 9 | 6,234
Cancer 8 | 2,346
glioblastoma 8 | 5,572
lung cancer 8 | 4,466
psoriasis 8 | 6,685
lung carcinoma 6 | 2,844
malignant mesothelioma 6 | 3,162
osteosarcoma 6 | 7,933
group 4 medulloblastoma 5 | 1,875
juvenile dermatomyositis 5 | 1,189
subependymal giant cell astrocytoma 5 | 2,287
Influenza 4 | 142
cutaneous lupus erythematosus 4 | 1,056
dermatomyositis 4 | 933
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
lung adenocarcinoma 4 | 2,713
Asthma 3 | 349
Breast cancer 3 | 3,094
Carcinoma 3 | 2,147
Herpes simplex 3 | 19
Multiple Sclerosis 3 | 498
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
astrocytoma 3 | 1,493
breast carcinoma 3 | 1,614
cystic fibrosis 3 | 1,665
diabetes mellitus 3 | 1,663
gastric carcinoma 3 | 832
invasive ductal carcinoma 3 | 2,950
pancreatic cancer 3 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
pediatric high grade glioma 3 | 2,712
pilocytic astrocytoma 3 | 3,086
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 674
tuberculosis 3 | 1,557
ulcerative colitis 3 | 2,087
Age related macular degeneration 2 | 84
Amyotrophic Lateral Sclerosis 2 | 431
Arthritis 2 | 248
Colorectal Neoplasms 2 | 217
Duchenne muscular dystrophy 2 | 602
Encephalitis 2 | 54
Gastritis 2 | 44
Gaucher disease type 1 2 | 171
Hantavirus pulmonary syndrome 2 | 7
Hypersensitivity reaction type II disease 2 | 235
IGA Glomerulonephritis 2 | 454
Inflammation 2 | 109
Liver disease 2 | 219
Lung disease 2 | 132
Multiple myeloma 2 | 1,327
Myofibrillar myopathy 1 2 | 5
Myofibrillar myopathy 3 2 | 4
Neoplasm Metastasis 2 | 138
Perinatal necrotizing enterocolitis 2 | 18
Pick's disease 2 | 14
Reperfusion Injury 2 | 84
Respiratory Syncytial Virus Infections 2 | 5
Rheumatoid Arthritis 2 | 1,160
active Crohn's disease 2 | 918
acute myeloid leukemia 2 | 780
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
aldosterone-producing adenoma 2 | 664
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 2,514
group 3 medulloblastoma 2 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
non-small cell lung cancer 2 | 2,798
periodontitis 2 | 269
Brain disease 1 | 83
Congenital heart disease 1 | 63
Fatty Liver 1 | 48
Fatty liver disease 1 | 84
Frontotemporal dementia 1 | 41
Gaucher disease type 3 1 | 76
Hemolytic anemia 1 | 66
Hypogonadism 1 | 70
Leptospirosis 1 | 17
Liver Cirrhosis 1 | 101
Lupus erythematosus 1 | 80
Mastitis 1 | 48
Melanoma 1 | 261
Meningitis 1 | 46
Neonatal abstinence syndrome 1 | 9
Neoplasm Invasiveness 1 | 127
Neurogenic bowel 1 | 6
Non-alcoholic Fatty Liver Disease 1 | 40
Panic disorder 1 | 55
Pulmonary valve stenosis 1 | 10
Rhinitis 1 | 46
Severe acute respiratory syndrome 1 | 26
Stevens-Johnson syndrome 1 | 78
Vitiligo 1 | 71
non-inflammatory breast cancer 1 | 208
ovarian neoplasm 1 | 97

Tissue

Blood and immune system 18 | 17,995
Cardiovascular System 18 | 17,958
Digestive Tract 18 | 18,473
Endocrine System 18 | 18,512
Female tissues 18 | 18,647
Liver and Pancreas 18 | 18,136
Male tissues 18 | 17,969
Nervous System 18 | 18,561
Urinary Tract 18 | 18,444
Respiratory system 17 | 17,484
Skin and soft tissues 17 | 18,115

Target Family

Non-IDG 13 | 11,971
Kinase 2 | 634
Transcription Factor 2 | 1,400
Enzyme 1 | 4,146

Reactome Pathway

Activation of IRF3/IRF7 mediat... 18 | 18
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.21113 124.2 150
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG 56.7 150
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.06784 1308.8 971
Toll-like receptor 3 TLR3 Tchem Non-IDG -3.00214 1147.2 751
Lymphocyte antigen 96 LY96 Tbio Non-IDG -2.69962 490.7 314
TIR domain-containing adapter molecule 2 TICAM2 Tbio Non-IDG -0.56310 11.6 230
TIR domain-containing adapter molecule 1 TICAM1 Tbio Non-IDG -1.44846 31.8 191
Polyubiquitin-C UBC Tbio Non-IDG -2.87012 56.7 130
Polyubiquitin-B UBB Tbio Non-IDG 92.3 370
Serine/threonine-protein kinase TBK1 TBK1 Tchem Kinase -2.64096 447.9 420