Development Level

Tbio 18 | 11,178
Tchem 10 | 1,885
Tclin 1 | 612
Tdark 1 | 6,569

IMPC Phenotype

decreased mean corpuscular vol... 2 | 79
hyperactivity 2 | 148
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
abnormal bone mineralization 1 | 38
abnormal glucose homeostasis 1 | 4
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
edema 1 | 59
enlarged lymph nodes 1 | 37
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
thrombocytosis 1 | 27

Disease

ovarian cancer 21 | 8,297
Cancer 20 | 2,388
medulloblastoma, large-cell 20 | 6,086
atypical teratoid / rhabdoid tumor 19 | 4,971
osteosarcoma 19 | 7,766
glioblastoma 16 | 5,635
psoriasis 15 | 6,514
Carcinoma 14 | 11,192
adult high grade glioma 14 | 3,701
lung cancer 14 | 4,607
ependymoma 13 | 4,559
Breast cancer 10 | 3,469
group 4 medulloblastoma 10 | 1,806
malignant mesothelioma 10 | 3,135
lung adenocarcinoma 9 | 2,627
Astrocytoma, Pilocytic 8 | 3,006
Bipolar Disorder 8 | 646
Schizophrenia 8 | 1,136
astrocytic glioma 8 | 2,530
oligodendroglioma 8 | 2,768
primitive neuroectodermal tumor 8 | 2,957
group 3 medulloblastoma 7 | 4,002
pancreatic cancer 7 | 2,322
Breast Neoplasms 6 | 423
hepatocellular carcinoma 6 | 536
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,902
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,204
Multiple myeloma 5 | 1,296
acute myeloid leukemia 5 | 760
acute quadriplegic myopathy 5 | 1,133
colon cancer 5 | 1,428
dermatomyositis 5 | 941
diabetes mellitus 5 | 1,683
ductal carcinoma in situ 5 | 1,686
invasive ductal carcinoma 5 | 2,867
juvenile dermatomyositis 5 | 1,147
non-small cell lung cancer 5 | 2,799
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,911
Carcinoma, Hepatocellular 4 | 217
Cell Transformation, Neoplastic 4 | 90
Chronic Lymphocytic Leukemia 4 | 254
Epilepsy 4 | 775
Esophageal Neoplasms 4 | 68
Leukemia, Lymphocytic, Chronic, B-Cell 4 | 33
Liver carcinoma 4 | 229
Mammary Neoplasms 4 | 403
Neoplastic Cell Transformation 4 | 83
Seizures 4 | 584
Waldenstrons macroglobulinemia 4 | 742
adrenocortical carcinoma 4 | 1,385
breast carcinoma 4 | 1,589
nasopharyngeal carcinoma 4 | 1,024
primary pancreatic ductal adenocarcinoma 4 | 1,071
spina bifida 4 | 1,053
subependymal giant cell astrocytoma 4 | 2,230
tuberculosis 4 | 1,963
ulcerative colitis 4 | 1,765
Adenocarcinoma 3 | 116
Adenocarcinoma of lung (disorder) 3 | 59
Alzheimer's disease 3 | 640
Brain Ischemia 3 | 107
Carcinoma, Squamous Cell 3 | 107
Colorectal Neoplasms 3 | 235
Depressive disorder 3 | 401
Diabetes Mellitus, Experimental 3 | 101
Diabetes Mellitus, Type 2 3 | 136
High forehead 3 | 101
Kidney cancer 3 | 2,548
Kidney disease 3 | 411
Liver Cirrhosis, Experimental 3 | 733
Liver Neoplasms, Experimental 3 | 58
Lung Neoplasms 3 | 217
Lymphoid leukemia 3 | 156
Melanoma 3 | 689
Mesothelioma, Malignant 3 | 103
Microstomia 3 | 76
Neoplasm Metastasis 3 | 160
Parkinson's disease 3 | 378
Pick disease 3 | 1,856
Polycystic ovary syndrome 3 | 348
Prostatic Neoplasms 3 | 472
Rheumatoid arthritis 3 | 1,156
Squamous cell carcinoma 3 | 125
Stomach Neoplasms 3 | 287
Tall forehead 3 | 101
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 492
gastric cancer 3 | 445
interstitial cystitis 3 | 2,237
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,872
medulloblastoma 3 | 702
non primary Sjogren syndrome sicca 3 | 861
pancreatic carcinoma 3 | 555
pituitary cancer 3 | 1,915
tuberculosis and treatment for 6 months 3 | 399
Down syndrome 2 | 480
Male infertility 2 | 199
Mental Depression 2 | 325
Vascular disease 2 | 294
esophageal adenocarcinoma 2 | 696
urothelial carcinoma 2 | 303

Tissue

Blood and immune system 29 | 16,909
Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 20 | 12,091
Transcription Factor 6 | 1,400
Kinase 3 | 634
Enzyme 1 | 4,145

Reactome Pathway

Activation of BH3-only protein... 30 | 30
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Apoptosis-stimulating of p53 protein 2 TP53BP2 Tbio Non-IDG -1.85307 72.5 189
14-3-3 protein eta YWHAH Tchem Non-IDG -1.62035 42.0 212
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Calcineurin subunit B type 1 PPP3R1 Tbio Non-IDG -2.60752 391.4 125
14-3-3 protein gamma YWHAG Tbio Non-IDG -1.87443 78.9 387
Tumor protein p73 TP73 Tbio Transcription Factor -1.92832 82.6 708
Bcl2-associated agonist of cell death BAD Tchem Non-IDG -2.08893 103.4 2565
14-3-3 protein epsilon YWHAE Tchem Non-IDG -2.23108 170.5 348