Development Level

Tbio 18 | 10,625
Tchem 11 | 1,890
Tclin 1 | 602
Tdark 1 | 7,003

IMPC Term

increased circulating alkaline... 2 | 119
abnormal bone mineralization 1 | 55
abnormal glucose homeostasis 1 | 5
abnormal respiratory quotient 1 | 9
abnormal retina morphology 1 | 100
abnormal skin morphology 1 | 23
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
increased circulating LDL chol... 1 | 15
increased circulating choleste... 1 | 53
increased leukocyte cell numbe... 1 | 37
preweaning lethality, complete... 1 | 633
thrombocytosis 1 | 23

Disease

Cancer 22 | 2,346
ovarian cancer 22 | 8,484
medulloblastoma, large-cell 20 | 6,234
osteosarcoma 19 | 7,933
atypical teratoid / rhabdoid tumor 18 | 4,369
psoriasis 15 | 6,685
glioblastoma 14 | 5,572
lung cancer 14 | 4,466
adult high grade glioma 12 | 2,148
Breast cancer 10 | 3,094
lung adenocarcinoma 9 | 2,713
malignant mesothelioma 9 | 3,162
ependymoma 8 | 2,514
oligodendroglioma 8 | 2,849
pilocytic astrocytoma 8 | 3,086
primitive neuroectodermal tumor 8 | 3,031
astrocytic glioma 7 | 2,241
group 4 medulloblastoma 7 | 1,875
medulloblastoma 7 | 1,524
pancreatic cancer 7 | 2,300
diabetes mellitus 6 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
Mammary Neoplasms 5 | 410
Multiple myeloma 5 | 1,327
Schizophrenia 5 | 501
acute myeloid leukemia 5 | 780
acute quadriplegic myopathy 5 | 1,157
colon cancer 5 | 1,475
dermatomyositis 5 | 933
ductal carcinoma in situ 5 | 1,745
hepatocellular carcinoma 5 | 532
invasive ductal carcinoma 5 | 2,950
juvenile dermatomyositis 5 | 1,189
non-small cell lung cancer 5 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
Alzheimer's disease 4 | 644
Chronic Lymphocytic Leukemia 4 | 242
Colorectal Neoplasms 4 | 217
Esophageal Neoplasms 4 | 67
Kidney disease 4 | 396
Liver carcinoma 4 | 217
Neoplastic Cell Transformation 4 | 81
Parkinson's disease 4 | 364
Prostatic Neoplasms 4 | 471
Squamous cell carcinoma 4 | 94
Waldenstrons macroglobulinemia 4 | 765
adrenocortical carcinoma 4 | 1,427
nasopharyngeal carcinoma 4 | 1,056
pancreatic carcinoma 4 | 567
posterior fossa group A ependymoma 4 | 1,511
primary pancreatic ductal adenocarcinoma 4 | 1,271
spina bifida 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 1,557
tuberculosis and treatment for 6 months 4 | 686
ulcerative colitis 4 | 2,087
Adenocarcinoma 3 | 115
Adenoma 3 | 165
Asthma 3 | 349
Brain Ischemia 3 | 87
Brain disease 3 | 83
Diabetes Mellitus, Experimental 3 | 106
Lung Neoplasms 3 | 171
Lung disease 3 | 132
Lymphoid leukemia 3 | 69
Neoplasm Metastasis 3 | 138
Obesity 3 | 616
Pick disease 3 | 1,893
Rheumatoid Arthritis 3 | 1,160
Stomach Neoplasms 3 | 282
Toxic encephalopathy 3 | 131
Vascular disease 3 | 281
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
breast carcinoma 3 | 1,614
gastric cancer 3 | 430
group 3 medulloblastoma 3 | 2,254
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
non primary Sjogren syndrome sicca 3 | 840
pediatric high grade glioma 3 | 2,712
pituitary cancer 3 | 1,972
posterior fossa group B ependymoma 3 | 1,530
sonic hedgehog group medulloblastoma 3 | 1,482
Arthritis 2 | 248
Atopic dermatitis 2 | 944
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Down syndrome 2 | 548
Eye disease 2 | 55
Heart disease 2 | 279
Hypertensive disease 2 | 193
IGA Glomerulonephritis 2 | 454
Male infertility 2 | 170
Metabolic syndrome X 2 | 155
Polycystic Ovary Syndrome 2 | 332
Reperfusion Injury 2 | 84
cystic fibrosis 2 | 1,665
esophageal adenocarcinoma 2 | 737
non-small cell lung carcinoma 2 | 413
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 31 | 17,995
Digestive Tract 31 | 18,473
Female tissues 31 | 18,647
Liver and Pancreas 31 | 18,136
Male tissues 31 | 17,969
Nervous System 31 | 18,561
Respiratory system 31 | 17,484
Urinary Tract 31 | 18,444
Cardiovascular System 30 | 17,958
Endocrine System 30 | 18,512
Skin and soft tissues 30 | 18,115

Target Family

Non-IDG 20 | 11,971
Transcription Factor 6 | 1,400
Kinase 4 | 634
Enzyme 1 | 4,146

Reactome Pathway

Activation of BH3-only protein... 31 | 31
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.65303 525.6 142
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.66052 440.9 327
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.35945 217.4 316
14-3-3 protein epsilon YWHAE Tchem Non-IDG -2.18406 158.6 309
Apoptosis-stimulating of p53 protein 2 TP53BP2 Tbio Non-IDG -1.80161 68.4 178
Bcl-2-like protein 11 BCL2L11 Tbio Non-IDG -3.11135 1340.6 903
Bcl-2-binding component 3 BBC3 Tbio Non-IDG 79.2 511
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.09170 79.2 511
14-3-3 protein zeta/delta YWHAZ Tbio Non-IDG -2.54857 362.3 648
BH3-interacting domain death agonist BID Tbio Non-IDG -1.78154 53.0 854