Development Level

Tbio 14 | 11,651
Tchem 1 | 1,388
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal embryo size 2 | 220
abnormal retinal vasculature m... 2 | 27
cataract 2 | 92
embryonic lethality prior to t... 2 | 278
impaired pupillary reflex 2 | 26
increased circulating choleste... 2 | 66
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal tail morphology 1 | 25
absent startle reflex 1 | 24
cleft palate 1 | 8
corneal opacity 1 | 32
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased spleen weight 1 | 10
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
fused cornea and lens 1 | 5
hemorrhage 1 | 23
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
limb grasping 1 | 41
narrow eye opening 1 | 12
no spontaneous movement 1 | 1
persistence of hyaloid vascula... 1 | 33

Disease

Cancer 9 | 2,499
Cleft Lip 7 | 141
Cleft Palate 7 | 271
lung cancer 7 | 4,740
psoriasis 7 | 6,694
Autosomal recessive predisposition 5 | 1,442
Carcinoma 5 | 11,493
Depressive disorder 5 | 409
LADD syndrome 5 | 9
group 3 medulloblastoma 5 | 4,104
malignant mesothelioma 5 | 3,232
Achondroplasia 4 | 21
Breast Neoplasms 4 | 445
Breast cancer 4 | 3,578
Mammary Neoplasms 4 | 425
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Acrocephalosyndactylia 3 | 17
Bipolar Disorder 3 | 666
Congenital absence of kidney 3 | 31
Craniofacial Abnormalities 3 | 151
Craniosynostosis 3 | 74
Cryptorchidism 3 | 296
Down syndrome 3 | 499
Downward slant of palpebral fissure 3 | 158
Generalized osteopenia 3 | 99
Hypospadias 3 | 53
Liver Cirrhosis 3 | 181
Lung disease 3 | 142
Mental Depression 3 | 333
Orbital separation excessive 3 | 244
Osteopenia 3 | 99
Osteoporosis 3 | 363
Parkinson's disease 3 | 392
Synostosis 3 | 15
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
Abnormality of body height 2 | 13
Absence of pubertal development 2 | 17
Absence of radius and ulna 2 | 15
Absence of secondary sex characteristics 2 | 22
Absent radius 2 | 15
Ankylosis 2 | 28
Anxiety 2 | 136
Anxiety disease 2 | 113
Capuchin ears 2 | 17
Choanal Atresia 2 | 42
Congenital hypoplasia of breast 2 | 25
Congenital hypoplasia of radius 2 | 23
Cupped ears (finding) 2 | 17
Decreased bone mineral density Z score 2 | 31
Decreased fertility 2 | 33
Decreased testosterone in males 2 | 28
Defective enamel matrix 2 | 35
Delayed Puberty 2 | 97
Dental Enamel Hypoplasia 2 | 43
Dental caries 2 | 164
Dysplasia of tooth enamel 2 | 35
Erectile dysfunction 2 | 32
Esophageal atresia 2 | 43
Eunuchoid habitus 2 | 14
Female hypogonadism syndrome 2 | 25
Gynecomastia 2 | 64
Hypochondroplasia 2 | 10
Hypodontia 2 | 81
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Increased female libido 2 | 13
Infantile uterus 2 | 23
Kallmann Syndrome 2 (disorder) 2 | 18
Lacrimal Duct Obstruction 2 | 16
Non-obstructive azoospermia 2 | 21
Obstruction of nasolacrimal duct 2 | 9
Peg shaped front tooth 2 | 6
Peg-shaped incisors 2 | 6
Periorbital fullness 2 | 9
Pointed front tooth 2 | 6
Pointed incisor 2 | 6
Primary physiologic amenorrhea 2 | 55
Pulmonary Fibrosis 2 | 106
Radial aplasia 2 | 15
Radial ray hypoplasia 2 | 23
Renal agenesis 2 | 29
Rotting teeth 2 | 73
Short ulnae 2 | 24
Small testicle 2 | 75
Sparse body hair 2 | 32
Testicular hypogonadism 2 | 21
Thanatophoric dysplasia 2 | 7
Thin dental enamel 2 | 35
Tooth Abnormalities 2 | 69
ULNAR HYPOPLASIA 2 | 24
Wide spaced nipples 2 | 46

Tissue

Endocrine System 15 | 18,159
Digestive Tract 14 | 17,369
Nervous System 14 | 16,725
Female tissues 13 | 17,400
Male tissues 13 | 17,142
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Blood and immune system 12 | 16,909
Liver and Pancreas 12 | 16,750
Respiratory system 11 | 16,393
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 15 | 12,091
Kinase 1 | 634

Reactome Pathway

Activated point mutants of FGF... 16 | 16
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor 22 FGF22 Tbio Non-IDG -1.15836 16.5 186
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.55166 363.0 320
Fibroblast growth factor 2 FGF2 Tchem Non-IDG -4.00542 10573.5 798
Fibroblast growth factor 3 FGF3 Tbio Non-IDG -2.29270 192.7 118
Fibroblast growth factor 4 FGF4 Tbio Non-IDG -2.60388 394.1 327
Fibroblast growth factor 6 FGF6 Tbio Non-IDG -1.56137 40.2 113
Fibroblast growth factor 5 FGF5 Tbio Non-IDG -2.07061 109.8 192
Fibroblast growth factor 16 FGF16 Tbio Non-IDG -1.75464 57.5 162
Fibroblast growth factor 18 FGF18 Tbio Non-IDG -1.89822 84.6 146
Fibroblast growth factor 20 FGF20 Tbio Non-IDG -1.71980 55.3 117