Development Level

Tchem 3 | 1,598
Tbio 2 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal rib morphology 1 | 10
decreased prepulse inhibition 1 | 82
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 5 | 11,493
psoriasis 5 | 6,694
Breast cancer 4 | 3,578
Cancer 4 | 2,499
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
ovarian cancer 4 | 8,520
Kidney cancer 3 | 2,613
Schizophrenia 3 | 1,160
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
juvenile dermatomyositis 3 | 1,187
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
Alcoholic Intoxication, Chronic 2 | 289
Astrocytoma, Pilocytic 2 | 3,081
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Cataract 2 | 297
DOID:2627 2 | 94
Depressive disorder 2 | 409
Endometrial cancer 2 | 311
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Fatigue 2 | 182
Frontal bossing 2 | 157
Glaucoma 2 | 239
Hypoplastic mandible condyle 2 | 275
Intellectual disability 2 | 1,016
Joint laxity 2 | 54
Lens Opacities 2 | 231
Liver cancer 2 | 604
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Myopia 2 | 176
Parkinson's disease 2 | 392
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
oligodendroglioma 2 | 2,850
pancreatic carcinoma 2 | 562
permanent atrial fibrillation 2 | 45
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
ulcerative colitis 2 | 1,819
AGAMMAGLOBULINEMIA 1, AUTOSOMAL RECESSIVE 1 | 8
Action Tremor 1 | 22
Agammaglobulinemia, non-Bruton type 1 | 8
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1 1 | 13
Birth length less than 3rd percentile 1 | 6
Bronchioloalveolar Adenocarcinoma 1 | 14
Cardiovascular Abnormalities 1 | 31
Cowden disease 1 | 18
Cutis marmorata 1 | 32
Dysthymic Disorder 1 | 17
Facial asymmetry 1 | 32
Fibrous skin tumor of tuberous sclerosis 1 | 18
Fissured tongue 1 | 25
Gastric Cancer, Hereditary Diffuse 1 | 12
Gastrointestinal Hemorrhage 1 | 52
Goiter 1 | 38
Hamartoma Syndrome, Multiple 1 | 10
Hematologic Neoplasms 1 | 22
Hyperphagia 1 | 23
Hyperthyroidism 1 | 53
Increased appetite (finding) 1 | 23
Infection of bone 1 | 19
Irritation - emotion 1 | 68
Lipodystrophy 1 | 40
Lymphoma, Large B-Cell, Diffuse 1 | 34
Macrocephaly 1 | 11
Macule 1 | 19
Malignant neoplasm of ovary 1 | 4
Mucosal telangiectasiae 1 | 14
Multiple, subcutaneous nodules 1 | 53
Noonan syndrome 1 | 34
Numerous nevi 1 | 5
Papule 1 | 43
Paranasal Sinus Diseases 1 | 34
Port-Wine Stain 1 | 8
Rectal Neoplasms 1 | 18
Recurrent skin infections 1 | 21
Rieger syndrome 1 | 8
Sinusitis 1 | 65
Stomach Carcinoma 1 | 11
Subcutaneous lipomas 1 | 9
Subcutaneous nodule 1 | 53
Terminal tremor 1 | 20
Thin hypoplastic alae nasi 1 | 51
Thyroid Gland Follicular Adenoma 1 | 9
Thyroiditis 1 | 29

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Liver and Pancreas 5 | 16,750

Target Family

Kinase 3 | 634
Non-IDG 3 | 12,091

Reactome Pathway

Activated NTRK2 signals throug... 6 | 6
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GRB2-associated-binding protein 1 GAB1 Tbio Non-IDG -1.55563 50.4 268
BDNF/NT-3 growth factors receptor NTRK2 Tchem Kinase -3.14477 1170.3 947
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -3.02404 981.4 501
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.51919 316.4 758
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform PIK3CA Tclin Kinase -3.04988 1076.8 484
Neurotrophin-4 NTF4 Tbio Non-IDG -2.58153 360.5 446