Development Level

Tchem 3 | 1,598
Tbio 2 | 11,445

IMPC Phenotype

abnormal rib morphology 1 | 10
decreased prepulse inhibition 1 | 82
hypoactivity 1 | 132
preweaning lethality, incomple... 1 | 499

Disease

adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
Carcinoma 3 | 11,493
Schizophrenia 3 | 1,160
astrocytic glioma 3 | 2,597
esophageal adenocarcinoma 3 | 737
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
pituitary cancer 3 | 1,972
psoriasis 3 | 6,694
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Atopic dermatitis 2 | 952
Breast cancer 2 | 3,578
Depressive disorder 2 | 409
Mental Depression 2 | 333
Parkinson's disease 2 | 392
Pick disease 2 | 1,894
Toxic encephalopathy 2 | 141
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Alcoholic Intoxication, Chronic 1 | 289
Arthrogryposis 1 | 54
Autistic Disorder 1 | 364
Bipolar Disorder 1 | 666
Brain disease 1 | 96
Carcinoma, Hepatocellular 1 | 228
Cardiomyopathy, Dilated 1 | 83
Cardiovascular system disease 1 | 246
Cerebrovascular disease 1 | 238
Clenched hands 1 | 6
Cocaine-Related Disorders 1 | 92
Cognition Disorders 1 | 32
Common variable immunodeficiency 1 | 101
Dementia 1 | 175
Down syndrome 1 | 499
Endometrial cancer 1 | 311
Epilepsy 1 | 792
Glioma 1 | 74
Global developmental delay, severe 1 | 47
Heart failure 1 | 162
Hirsutism 1 | 47
Huntington's disease 1 | 76
Hyperactive behavior 1 | 91
Lissencephaly 1 | 69
Liver cancer 1 | 604
Liver carcinoma 1 | 240
Liver diseases 1 | 87
Lymphedema 1 | 42
Major Depressive Disorder 1 | 301
Melanoma 1 | 711
Mood Disorders 1 | 184
Mouth Neoplasms 1 | 55
Neoplasm Metastasis 1 | 168
Nephrosis 1 | 21
Nerve Degeneration 1 | 121
Neuroblastoma 1 | 80
Neurodegenerative disease 1 | 414
Pilocytic astrocytoma 1 | 56
Prenatal onset 1 | 139
Reflex, Deep Tendon, Absent 1 | 92
Retinitis pigmentosa 47 1 | 4
Severe psychomotor retardation 1 | 47
Skin cancer 1 | 469
Status Epilepticus 1 | 98
Unipolar Depression 1 | 250
Waldenstrons macroglobulinemia 1 | 765
astrocytoma 1 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
breast carcinoma 1 | 1,638
chorea-acanthocytosis 1 | 12
cystic fibrosis 1 | 1,696
medulloblastoma 1 | 720
nasopharyngeal carcinoma 1 | 1,058
nephrosclerosis 1 | 333
pancreatic cancer 1 | 2,398
pediatric high grade glioma 1 | 1,064
permanent atrial fibrillation 1 | 45
sarcoidosis 1 | 370
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Enzyme 2 | 4,145
Kinase 2 | 634
Non-IDG 1 | 12,091

Reactome Pathway

Activated NTRK2 signals throug... 5 | 5
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BDNF/NT-3 growth factors receptor NTRK2 Tchem Kinase -3.14477 1170.3 947
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.94674 87.1 452
Cyclin-dependent-like kinase 5 CDK5 Tchem Kinase -3.06393 1238.4 694
T-lymphoma invasion and metastasis-inducing protein 1 TIAM1 Tbio Non-IDG -2.25288 186.4 142
Cyclin-dependent kinase 5 activator 1 CDK5R1 Tchem Enzyme -1.77914 52.4 217