Development Level

Tbio 12 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal gait 1 | 69
abnormal hair growth 1 | 10
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal testis morphology 1 | 43
head bobbing 1 | 5
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
small testis 1 | 58
thrombocytosis 1 | 27

Disease

Astrocytoma, Pilocytic 12 | 3,081
adult high grade glioma 12 | 3,801
ependymoma 12 | 4,679
glioblastoma 12 | 5,792
atypical teratoid / rhabdoid tumor 11 | 5,112
medulloblastoma, large-cell 11 | 6,241
oligodendroglioma 11 | 2,850
Carcinoma 10 | 11,493
astrocytic glioma 10 | 2,597
Pick disease 9 | 1,894
primitive neuroectodermal tumor 9 | 3,035
group 3 medulloblastoma 8 | 4,104
psoriasis 8 | 6,694
lung cancer 7 | 4,740
subependymal giant cell astrocytoma 7 | 2,287
Kidney cancer 6 | 2,613
Schizophrenia 6 | 1,160
malignant mesothelioma 6 | 3,232
ovarian cancer 6 | 8,520
osteosarcoma 5 | 7,950
interstitial cystitis 4 | 2,312
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
Bipolar Disorder 3 | 666
Botulism 3 | 24
Breast cancer 3 | 3,578
Cognitive delay 3 | 608
Congenital Myasthenic Syndromes, Presynaptic 3 | 8
Congenital myasthenic syndrome 3 | 25
Epilepsy 3 | 792
Global developmental delay 3 | 608
Mental and motor retardation 3 | 608
Myasthenic Syndromes, Congenital 3 | 16
Parkinson's disease 3 | 392
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
Alzheimer's disease 2 | 658
Attention deficit hyperactivity disorder 2 | 278
Autistic Disorder 2 | 364
Blepharoptosis 2 | 231
Cataract 7 2 | 32
Cerebellar Ataxia 2 | 304
Depressive disorder 2 | 409
Gaucher disease type 1 2 | 180
Hypomyelinating leukodystrophy 6 2 | 26
Intellectual disability 2 | 1,016
Major Depressive Disorder 2 | 301
Mental Depression 2 | 333
Nager acrofacial dysostosis 2 | 21
Neurodegenerative disease 2 | 414
Neurodevelopmental Disorders 2 | 70
Oppositional defiant disorder 2 | 17
Psychotic Disorders 2 | 151
Reduced fetal movement 2 | 51
Rheumatoid arthritis 2 | 1,191
Severe mental retardation (I.Q. 20-34) 2 | 99
Tetanus 2 | 68
Unipolar Depression 2 | 250
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
Abnormal color vision 1 | 31
Auricular malformation 1 | 41
Coloboma 1 | 51
Color vision defect 1 | 33
Color vision defect, severe 1 | 31
Cone dystrophy 1 | 71
Cone/cone-rod dystrophy 1 | 20
Congenital fibrosis of the extraocular muscles 1 | 13
Early myoclonic encephalopathy 1 | 15
Epileptic encephalopathy 1 | 26
Exocrine pancreatic insufficiency 1 | 32
Fundus dystrophy 1 | 83
Fused vertebrae 1 | 25
Griscelli syndrome 1 | 24
Hyperkyphosis 1 | 111
Kyphosis deformity of spine 1 | 114
Metatarsus Varus 1 | 24
Neonatal onset 1 | 21
Poor speech 1 | 37
Preauricular Fistulae, Congenital 1 | 27
Preauricular dimple 1 | 27
Preauricular sinus 1 | 27
Precocious Puberty 1 | 28
Problems speaking 1 | 37
Pulmonary Fibrosis 1 | 106
Simple ear 1 | 41
Spinal fusion 1 | 25
Toeing-in 1 | 24
Tonic - clonic seizures 1 | 44
Vertebral body fusion 1 | 25
Wernicke encephalopathy 1 | 12
Wolf-Hirschhorn syndrome 1 | 32
cone-rod dystrophy 1 | 59

Tissue

Digestive Tract 16 | 17,369
Female tissues 16 | 17,400
Skin and soft tissues 16 | 17,230
Endocrine System 15 | 18,159
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Urinary Tract 15 | 16,678
Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192

Target Family

Non-IDG 13 | 12,091
Transporter 2 | 473
Enzyme 1 | 4,145

Reactome Pathway

Acetylcholine Neurotransmitter... 16 | 16
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peripheral-type benzodiazepine receptor-associated protein 1 TSPOAP1 Tbio Non-IDG -0.53932 4.30 18
Regulating synaptic membrane exocytosis protein 1 RIMS1 Tbio Non-IDG -1.95711 85.7 11
Vesicle-associated membrane protein 2 VAMP2 Tbio Non-IDG -2.53335 323.7 203
Liprin-alpha-3 PPFIA3 Tdark Non-IDG -1.44046 26.8 42
Syntaxin-binding protein 1 STXBP1 Tbio Non-IDG -2.30714 221.0 351
Liprin-alpha-4 PPFIA4 Tdark Non-IDG 0.13 1.07 31
Liprin-alpha-2 PPFIA2 Tbio Non-IDG -0.44401 2.81 63
Synaptotagmin-1 SYT1 Tbio Non-IDG -2.66042 455.0 616
Synaptosomal-associated protein 25 SNAP25 Tbio Non-IDG -2.61491 385.0 821
Protein unc-13 homolog B UNC13B Tbio Non-IDG -2.08635 111.4 161