Development Level

Tbio 18 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 3 | 220
embryonic growth retardation 3 | 106
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
anophthalmia 2 | 33
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain morphology 1 | 10
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta morphology 1 | 5
abnormal placenta size 1 | 20
abnormal skin coloration 1 | 25
brachydactyly 1 | 19
decreased circulating alanine ... 1 | 47
decreased circulating glucose ... 1 | 126
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
edema 1 | 59
increased circulating alanine ... 1 | 13
increased circulating glucose ... 1 | 24
increased hematocrit 1 | 46
increased mean corpuscular vol... 1 | 92
microphthalmia 1 | 26
pallor 1 | 34
prenatal lethality 1 | 28
syndactyly 1 | 23
urinary bladder obstruction 1 | 4

Disease

ovarian cancer 15 | 8,520
lung cancer 10 | 4,740
osteosarcoma 9 | 7,950
Carcinoma 8 | 11,493
glioblastoma 8 | 5,792
medulloblastoma, large-cell 8 | 6,241
psoriasis 8 | 6,694
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
adrenocortical carcinoma 6 | 1,428
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
Breast cancer 5 | 3,578
Cancer 5 | 2,499
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
Atopic dermatitis 4 | 952
Endometriosis 4 | 540
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
ductal carcinoma in situ 4 | 1,745
malignant mesothelioma 4 | 3,232
primitive neuroectodermal tumor 4 | 3,035
ulcerative colitis 4 | 1,819
Pick disease 3 | 1,894
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
esophageal adenocarcinoma 3 | 737
non primary Sjogren syndrome sicca 3 | 891
oligodendroglioma 3 | 2,850
Anemia 2 | 365
Kidney cancer 2 | 2,613
Multiple myeloma 2 | 1,332
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Pick's disease 2 | 15
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
diabetes mellitus 2 | 1,728
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung carcinoma 2 | 2,843
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group A ependymoma 2 | 468
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
Acquired metabolic disease 1 | 336
Alzheimer's disease 1 | 658
Amyotrophic lateral sclerosis 1 | 451
Arsenic Poisoning 1 | 62
Arthritis, Juvenile 1 | 126
Astrocytoma, Pilocytic 1 | 3,081
Breast Neoplasms 1 | 445
DOID:9917 1 | 31
Dermatologic disorders 1 | 93
Diffuse large B-cell lymphoma 1 | 39
Duchenne muscular dystrophy 1 | 601
Epilepsy 1 | 792
Exophthalmos 1 | 112
Gaucher disease type 1 1 | 180
Gingival Hyperplasia 1 | 34
Gingival Hypertrophy 1 | 34
Gingival Overgrowth 1 | 36
Juvenile arthritis 1 | 126
Liver Cirrhosis, Experimental 1 | 769
Mammary Neoplasms 1 | 425
Neuronal ceroid lipofuscinosis 1 | 28
Neuronal ceroid lipofuscinosis 2 1 | 17
Polycystic ovary syndrome 1 | 360
Profound Mental Retardation 1 | 31
Profound intellectual disabilities 1 | 31
Seizures 1 | 596
Skin Diseases 1 | 71
Spinocerebellar ataxia type 1 1 | 16
Syringomyelia 1 | 15
Toxoplasmosis 1 | 17
Type 2 diabetes mellitus 1 | 272
Varicocele 1 | 26
aldosterone-producing adenoma 1 | 665
dermatomyositis 1 | 966
interstitial lung disease 1 | 298
juvenile dermatomyositis 1 | 1,187
limb girdle muscular dystrophy 2B 1 | 40
medulloblastoma 1 | 720
mucosa-associated lymphoid tissue lymphoma 1 | 484
non diabetic and post-ischemic heart failure 1 | 200
non-small cell lung carcinoma 1 | 317
pituitary cancer 1 | 1,972
sarcoidosis 1 | 370
sonic hedgehog group medulloblastoma 1 | 467
tuberculosis 1 | 2,010

Tissue

Blood and immune system 22 | 16,909
Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678

Target Family

Non-IDG 12 | 12,091
Enzyme 9 | 4,145
Kinase 1 | 634

Reactome Pathway

APC/C:Cdc20 mediated degradati... 22 | 22
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Anaphase-promoting complex subunit 10 ANAPC10 Tbio Enzyme -1.23751 18.1 156
Anaphase-promoting complex subunit 11 ANAPC11 Tbio Enzyme -1.27406 17.9 239
Anaphase-promoting complex subunit 2 ANAPC2 Tbio Enzyme -0.45557 2.44 166
Anaphase-promoting complex subunit 4 ANAPC4 Tbio Enzyme 0.43 0.13 156
Anaphase-promoting complex subunit 7 ANAPC7 Tbio Enzyme -0.17118 1.40 73
Cell division cycle protein 23 homolog CDC23 Tbio Non-IDG -1.50528 30.4 191
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Anaphase-promoting complex subunit 15 ANAPC15 Tdark Enzyme -0.41378 2.22 27