Development Level

Tbio 43 | 10,625
Tchem 15 | 1,890
Tclin 8 | 602
Tdark 1 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633
vertebral fusion 2 | 23
abnormal bone structure 1 | 131
abnormal hair growth 1 | 8
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating insulin ... 1 | 75
decreased fasted circulating g... 1 | 49
impaired glucose tolerance 1 | 52
vertebral transformation 1 | 12

Disease

ovarian cancer 47 | 8,484
Multiple myeloma 29 | 1,327
lung cancer 29 | 4,466
psoriasis 29 | 6,685
osteosarcoma 25 | 7,933
glioblastoma 23 | 5,572
HIV Infections 15 | 100
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
Waldenstrons macroglobulinemia 11 | 765
atypical teratoid / rhabdoid tumor 11 | 4,369
dermatomyositis 11 | 933
medulloblastoma, large-cell 11 | 6,234
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
Breast cancer 10 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
lung adenocarcinoma 10 | 2,713
malignant mesothelioma 10 | 3,162
non-small cell lung cancer 10 | 2,798
astrocytoma 9 | 1,493
lung carcinoma 9 | 2,844
Cancer 8 | 2,346
diabetes mellitus 8 | 1,663
pancreatic cancer 8 | 2,300
Pick disease 7 | 1,893
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
non primary Sjogren syndrome sicca 7 | 840
ependymoma 6 | 2,514
interstitial cystitis 6 | 2,299
oligodendroglioma 6 | 2,849
primary pancreatic ductal adenocarcinoma 6 | 1,271
ulcerative colitis 6 | 2,087
Mantle cell lymphoma 5 | 18
Rheumatoid Arthritis 5 | 1,160
invasive ductal carcinoma 5 | 2,950
pediatric high grade glioma 5 | 2,712
pilocytic astrocytoma 5 | 3,086
primitive neuroectodermal tumor 5 | 3,031
subependymal giant cell astrocytoma 5 | 2,287
astrocytic glioma 4 | 2,241
cutaneous lupus erythematosus 4 | 1,056
juvenile dermatomyositis 4 | 1,189
medulloblastoma 4 | 1,524
primary Sjogren syndrome 4 | 789
progressive supranuclear palsy 4 | 674
Alzheimer's disease 3 | 644
Diabetes Mellitus, Non-Insulin-Dependent 3 | 157
Diaphragmatic Hernia 3 | 40
IGA Glomerulonephritis 3 | 454
Idiopathic pulmonary fibrosis 3 | 21
Lung disease 3 | 132
Neurodegenerative disease 3 | 383
Pneumonia 3 | 133
Pulmonary alveolar proteinosis 3 | 13
Respiratory failure 3 | 30
Stevens-Johnson syndrome 3 | 78
active Crohn's disease 3 | 918
acute myeloid leukemia 3 | 780
adult high grade glioma 3 | 2,148
cystic fibrosis 3 | 1,665
esophageal adenocarcinoma 3 | 737
group 3 medulloblastoma 3 | 2,254
interstitial lung disease 3 | 291
maturity-onset diabetes of the young 3 | 28
pituitary cancer 3 | 1,972
posterior fossa group A ependymoma 3 | 1,511
posterior fossa group B ependymoma 3 | 1,530
tuberculosis 3 | 1,557
Anemia 2 | 252
Animal Mammary Neoplasms 2 | 136
Aspergillosis 2 | 23
Carcinoma 2 | 2,147
Chronic obstructive pulmonary disease 2 | 146
Colorectal Neoplasms 2 | 217
Crohn's disease 2 | 304
Diabetes Mellitus, Insulin-Dependent 2 | 76
Diabetes mellitus type 2 2 | 69
Diarrhea 2 | 155
Epilepsy 2 | 346
Hyperglycemia 2 | 120
Hyperinsulinism 2 | 63
Hypertensive Emergencies 2 | 10
Hypoglycemia 2 | 81
Lung Neoplasms 2 | 171
Mammary Neoplasms, Experimental 2 | 150
Myopathy 2 | 128
Osteoporosis 2 | 257
Pancreatic agenesis 2 | 14
Peripheral Neuropathy 2 | 303
Pick's disease 2 | 14
Polycystic Ovary Syndrome 2 | 332
Squamous cell carcinoma of esophagus 2 | 82
Treatment Refractory Type 2 Diabetes Mellitus 2 | 53
Vascular disease 2 | 281
chronic kidney disease 2 | 90
facioscapulohumeral dystrophy 2 | 286
gastric carcinoma 2 | 832
hepatocellular carcinoma 2 | 532
hereditary spastic paraplegia 2 | 313
periodontitis 2 | 269
tuberculosis and treatment for 6 months 2 | 686

Tissue

Blood and immune system 67 | 17,995
Digestive Tract 67 | 18,473
Endocrine System 67 | 18,512
Female tissues 67 | 18,647
Liver and Pancreas 67 | 18,136
Male tissues 67 | 17,969
Nervous System 67 | 18,561
Urinary Tract 67 | 18,444
Cardiovascular System 66 | 17,958
Respiratory system 66 | 17,484
Skin and soft tissues 66 | 18,115

Target Family

Enzyme 42 | 4,146
Non-IDG 22 | 11,971
Ion Channel 2 | 341
Transporter 1 | 473

Reactome Pathway

ABC transporter disorders 67 | 67
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pulmonary surfactant-associated protein A2 SFTPA2 Tbio Non-IDG -2.31137 207.3 90
Pulmonary surfactant-associated protein A1 SFTPA1 Tbio Non-IDG -2.01123 102.6 195
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.21113 124.2 150
26S proteasome non-ATPase regulatory subunit 8 PSMD8 Tbio Enzyme -1.35900 20.6 94
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG 56.7 150
Pulmonary surfactant-associated protein D SFTPD Tbio Non-IDG -2.76722 653.0 266
Cystic fibrosis transmembrane conductance regulator CFTR Tclin Ion Channel -3.74904 5988.4 267
Proteasome activator complex subunit 3 PSME3 Tbio Non-IDG -1.80641 78.9 225
Erlin-2 ERLIN2 Tbio Non-IDG -1.24538 18.7 148
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.83653 71.4 158