Development Level

Tbio 27 | 11,445
Tchem 5 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 2 | 239
abnormal behavior 1 | 298
abnormal digit morphology 1 | 10
abnormal kidney morphology 1 | 65
decreased IgM level 1 | 1
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
long tibia 1 | 25

Disease

Carcinoma 25 | 11,493
ovarian cancer 23 | 8,520
Autosomal recessive predisposition 15 | 1,442
Cognitive delay 15 | 608
Global developmental delay 15 | 608
Mental and motor retardation 15 | 608
osteosarcoma 15 | 7,950
psoriasis 15 | 6,694
medulloblastoma, large-cell 14 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Multiple myeloma 13 | 1,332
Muscle hypotonia 12 | 571
lung cancer 12 | 4,740
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
group 3 medulloblastoma 11 | 4,104
Cancer 10 | 2,499
Acidosis, Lactic 9 | 97
Dull intelligence 9 | 645
Epilepsy 9 | 792
Intellectual disability 9 | 1,016
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
lung adenocarcinoma 9 | 2,716
Breast cancer 8 | 3,578
Cerebellar Ataxia 8 | 304
Lactic acidemia 8 | 95
Seizures 8 | 596
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Astrocytoma, Pilocytic 7 | 3,081
Hypoglycemia 7 | 152
Infantile onset 7 | 238
Obesity 7 | 678
breast carcinoma 7 | 1,638
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
primitive neuroectodermal tumor 7 | 3,035
Highly variable clinical phenotype 6 | 150
Highly variable phenotype and severity 6 | 150
Highly variable phenotype, even within families 6 | 150
Increased serum lactate 6 | 60
Kidney cancer 6 | 2,613
Leigh disease 6 | 100
Phenotypic variability 6 | 150
Small head 6 | 374
Stomach Neoplasms 6 | 300
adult high grade glioma 6 | 3,801
ductal carcinoma in situ 6 | 1,745
lung carcinoma 6 | 2,843
malignant mesothelioma 6 | 3,232
pancreatic cancer 6 | 2,398
subependymal giant cell astrocytoma 6 | 2,287
ulcerative colitis 6 | 1,819
Cerebral atrophy 5 | 178
Chondroma 5 | 15
Failure to gain weight 5 | 365
Lactic acidosis 5 | 51
Low Vision 5 | 174
Nystagmus 5 | 317
Optic Atrophy 5 | 242
Pediatric failure to thrive 5 | 365
Pick disease 5 | 1,894
Visual Impairment 5 | 174
Von Hippel-Lindau disease 5 | 19
astrocytic glioma 5 | 2,597
colon cancer 5 | 1,478
ependymoma 5 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
Blepharoptosis 4 | 231
Degenerative brain disorder 4 | 100
Degenerative polyarthritis 4 | 115
Deglutition Disorders 4 | 132
Dystonia 4 | 164
Dystonic disease 4 | 106
Gastrointestinal Stromal Tumors 4 | 48
Heart failure 4 | 162
Hyperhidrosis disorder 4 | 81
Hyperreflexia 4 | 209
Impaired cognition 4 | 96
Increased sweating 4 | 81
Intestinal Obstruction 4 | 31
Mental impairment 4 | 95
Osteoarthritis 4 | 184
Papilloma 4 | 44
Paraganglioma 4 | 15
Persistent generalized lymphadenopathy 4 | 15
Phaeochromocytoma 4 | 20
Pyruvate decarboxylase deficiency 4 | 16
Schizophrenia 4 | 1,160
Short stature 4 | 531
Supratentorial atrophy 4 | 94
Sweating 4 | 81
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
non primary Sjogren syndrome sicca 4 | 891
tuberculosis 4 | 2,010

Tissue

Blood and immune system 33 | 16,909
Cardiovascular System 33 | 15,192
Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Respiratory system 33 | 16,393
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678

Target Family

Enzyme 25 | 4,145
Transporter 5 | 473
Non-IDG 3 | 12,091

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..