Development Level

Tbio 22 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 2 | 239
abnormal behavior 1 | 298
abnormal digit morphology 1 | 10
abnormal kidney morphology 1 | 65
decreased IgM level 1 | 1
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating choleste... 1 | 93
decreased lean body mass 1 | 135
embryonic lethality prior to t... 1 | 278
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
long tibia 1 | 25

Disease

Carcinoma 21 | 11,493
ovarian cancer 20 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Cognitive delay 13 | 608
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
Autosomal recessive predisposition 12 | 1,442
Multiple myeloma 10 | 1,332
Muscle hypotonia 10 | 571
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
Acidosis, Lactic 9 | 97
lung cancer 9 | 4,740
medulloblastoma, large-cell 9 | 6,241
Cerebellar Ataxia 8 | 304
Epilepsy 8 | 792
Lactic acidemia 8 | 95
Seizures 8 | 596
atypical teratoid / rhabdoid tumor 8 | 5,112
lung adenocarcinoma 8 | 2,716
Cancer 7 | 2,499
Dull intelligence 7 | 645
Intellectual disability 7 | 1,016
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
breast carcinoma 7 | 1,638
glioblastoma 7 | 5,792
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Breast cancer 6 | 3,578
Chondroma 6 | 15
Infantile onset 6 | 238
Leigh disease 6 | 100
Stomach Neoplasms 6 | 300
invasive ductal carcinoma 6 | 2,951
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
Degenerative polyarthritis 5 | 115
Highly variable clinical phenotype 5 | 150
Highly variable phenotype and severity 5 | 150
Highly variable phenotype, even within families 5 | 150
Increased serum lactate 5 | 60
Kidney cancer 5 | 2,613
Lactic acidosis 5 | 51
Low Vision 5 | 174
Multiple, subcutaneous nodules 5 | 53
Nystagmus 5 | 317
Optic Atrophy 5 | 242
Osteoarthritis 5 | 184
Papilloma 5 | 44
Persistent generalized lymphadenopathy 5 | 15
Phenotypic variability 5 | 150
Small head 5 | 374
Subcutaneous nodule 5 | 53
Visual Impairment 5 | 174
Von Hippel-Lindau disease 5 | 19
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
ductal carcinoma in situ 5 | 1,745
primitive neuroectodermal tumor 5 | 3,035
Astrocytoma, Pilocytic 4 | 3,081
Blepharoptosis 4 | 231
Cerebral atrophy 4 | 178
Deglutition Disorders 4 | 132
Dystonia 4 | 164
Dystonic disease 4 | 106
Failure to gain weight 4 | 365
Gastrointestinal Hemorrhage 4 | 52
Gastrointestinal Stromal Tumors 4 | 48
Gastrointestinal stromal tumor 4 | 62
Hemangioma 4 | 69
Hyperhidrosis disorder 4 | 81
Hypoglycemia 4 | 152
Impaired cognition 4 | 96
Increased sweating 4 | 81
Intestinal Obstruction 4 | 31
Mental impairment 4 | 95
Paraganglioma 4 | 15
Pediatric failure to thrive 4 | 365
Phaeochromocytoma 4 | 20
Polycythemia 4 | 25
Pyruvate decarboxylase deficiency 4 | 16
Short stature 4 | 531
Sweating 4 | 81
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
pancreatic cancer 4 | 2,398
ulcerative colitis 4 | 1,819
Adult onset 3 | 82
Big calvaria 3 | 147
Constipation 3 | 181
Dyschezia 3 | 135
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Macroglossia 3 | 65
Neonatal Hypotonia 3 | 64
Ophthalmoplegia 3 | 106
Tachycardia 3 | 43

Tissue

Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678

Target Family

Enzyme 22 | 4,145
Non-IDG 4 | 12,091
Transporter 1 | 473

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 27 | 27
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..