Development Level

Tbio 12 | 11,445
Tchem 5 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal QT variability 2 | 10
abnormal bone mineralization 1 | 38
abnormal cranium morphology 1 | 36
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating magnesiu... 1 | 13
decreased total body fat amoun... 1 | 207
impaired glucose tolerance 1 | 75
increased body temperature 1 | 9
increased circulating alkaline... 1 | 122
increased prepulse inhibition 1 | 32
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 10 | 11,493
ovarian cancer 9 | 8,520
Autosomal recessive predisposition 7 | 1,442
lung cancer 7 | 4,740
psoriasis 7 | 6,694
osteosarcoma 6 | 7,950
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung adenocarcinoma 5 | 2,716
Icterus 4 | 82
Muscle hypotonia 4 | 571
atypical teratoid / rhabdoid tumor 4 | 5,112
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Adenocarcinoma of lung 3 | 142
Atopic dermatitis 3 | 952
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Cataract 3 | 297
Cholecystitis 3 | 18
Cholelithiasis 3 | 33
Epilepsy 3 | 792
Galactosemia 3 | 19
Hepatomegaly 3 | 285
Hypoglycemia 3 | 152
Neuropathy 3 | 261
Normochromic anemia 3 | 6
Normocytic anemia 3 | 6
Schizophrenia 3 | 1,160
Seizures 3 | 596
Splenomegaly 3 | 190
active ulcerative colitis 3 | 764
astrocytic glioma 3 | 2,597
diabetes mellitus 3 | 1,728
esophageal adenocarcinoma 3 | 737
fructose-1,6-bisphosphatase deficiency 3 | 7
glioblastoma 3 | 5,792
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
nephrosclerosis 3 | 333
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
ulcerative colitis 3 | 1,819
Chemical and Drug Induced Liver Injury 2 | 195
Cognitive delay 2 | 608
Comatose 2 | 56
Congenital disorder of glycosylation 2 | 54
Congenital hemolytic anemia 2 | 32
Decreased tendon reflex 2 | 122
Diarrhea 2 | 253
Disease Models, Animal 2 | 155
Dull intelligence 2 | 645
Failure to gain weight 2 | 365
Global developmental delay 2 | 608
Glycogen storage disease 2 | 39
Increased bilirubin level (finding) 2 | 18
Intellectual disability 2 | 1,016
Lethargy 2 | 77
Liver Cirrhosis 2 | 181
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Metabolic acidosis 2 | 90
Multiple myeloma 2 | 1,332
Myocardial Ischemia 2 | 169
Myopathy 2 | 185
Nonspherocytic hemolytic anemia 2 | 6
Pediatric failure to thrive 2 | 365
Peripheral Neuropathy 2 | 134
Poor school performance 2 | 645
Prenatal onset 2 | 139
Stomach Neoplasms 2 | 300
Vomiting 2 | 116
active Crohn's disease 2 | 922
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
medulloblastoma, large-cell 2 | 6,241
nasopharyngeal carcinoma 2 | 1,058
pituitary cancer 2 | 1,972
Adenocarcinoma of lung (disorder) 1 | 60
Anemia, Hemolytic 1 | 55
Decreased motor NCV 1 | 22
Elevated heart rate 1 | 25
Fanconi syndrome 1 | 14
Hyperglycemia 1 | 137
Hyperkyphosis 1 | 111
Hypermethioninemia 1 | 11
Kyphosis deformity of spine 1 | 114
Myocardial Reperfusion Injury 1 | 37
Nausea 1 | 20
Respiratory Distress Syndrome, Adult 1 | 40
Steatohepatitis 1 | 44
Tyrosinemia 1 | 10
Wilson disease 1 | 16

Tissue

Blood and immune system 18 | 16,909
Cardiovascular System 18 | 15,192
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678

Target Family

Enzyme 13 | 4,145
Kinase 5 | 634

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 18 | 18
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorbitol dehydrogenase SORD Tchem Enzyme -2.18880 132.4 347
Triosephosphate isomerase TPI1 Tbio Enzyme -2.88127 742.8 315
Fructose-1,6-bisphosphatase 1 FBP1 Tchem Enzyme -2.06824 111.8 202
Fucose-1-phosphate guanylyltransferase FPGT Tbio Enzyme -1.12872 12.9 112
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 PFKFB1 Tbio Kinase -1.33284 17.6 214
14 kDa phosphohistidine phosphatase PHPT1 Tbio Enzyme -1.57078 34.7 255
Ketohexokinase KHK Tchem Kinase -1.99770 98.6 319
Aldose reductase AKR1B1 Tclin Enzyme -3.27314 1915.8 350
GDP-L-fucose synthase TSTA3 Tbio Enzyme -1.16563 14.3 231
Mannose-1-phosphate guanyltransferase beta GMPPB Tbio Enzyme -1.17283 16.0 118