Development Level

Tbio 7 | 11,651
Tchem 2 | 1,388

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
cataract 1 | 92
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
hypoactivity 1 | 132

Disease

Carcinoma 7 | 11,493
medulloblastoma, large-cell 5 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Autosomal recessive predisposition 4 | 1,442
Cancer 4 | 2,499
glioblastoma 4 | 5,792
non-small cell lung cancer 4 | 2,890
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Myocardial Infarction 3 | 151
atypical teratoid / rhabdoid tumor 3 | 5,112
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
Ancylostomiasis 2 | 6
Astrocytoma, Pilocytic 2 | 3,081
Chemical and Drug Induced Liver Injury 2 | 195
Hypertension 2 | 396
Kidney Failure 2 | 111
Liver Cirrhosis, Experimental 2 | 769
Melanoma 2 | 711
Myopathy 2 | 185
Pick disease 2 | 1,894
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Schizophrenia 2 | 1,160
Toxic encephalopathy 2 | 141
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
chronic rhinosinusitis 2 | 512
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
non primary Sjogren syndrome sicca 2 | 891
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
tuberculosis 2 | 2,010
Abnormal urinary amino-acid findings 1 | 38
Abnormality of metabolism/homeostasis 1 | 134
Amino Acid Metabolism, Inborn Errors 1 | 13
Aminoaciduria 1 | 38
Amyloidosis 1 | 67
Anemia, Hemolytic 1 | 55
Argininosuccinic aciduria 1 | 17
Atypical autism 1 | 26
Berylliosis 1 | 28
Carcinoma, Non-Small-Cell Lung 1 | 107
Cardiomyopathies 1 | 110
Chronic kidney disease stage 5 1 | 31
Congenital hemolytic anemia 1 | 32
Cystathioninuria 1 | 2
Cystinosis 1 | 14
Degenerative brain disorder 1 | 100
Deglutition Disorders 1 | 132
Dehydration 1 | 40
Delayed Puberty 1 | 97
Exocrine pancreatic insufficiency 1 | 32
Fanconi syndrome 1 | 14
Glycosuria 1 | 29
Homocystinuria 1 | 21
Hyperchloremic metabolic acidosis 1 | 5
Hyperhomocysteinemia 1 | 37
Hypermethioninemia 1 | 11
Hypohidrosis 1 | 34
Hypokalemia 1 | 52
Hypophosphatemia 1 | 40
Hypopigmentation disorder 1 | 25
Increased serum lactate 1 | 60
Increased serum pyruvate 1 | 9
Inflammatory myofibroblastic tumor 1 | 8
Knee joint valgus deformity 1 | 56
Long QT syndrome 1 | 39
MYELODYSPLASTIC SYNDROME 1 | 53
Microscopic hematuria 1 | 9
Muscle Cramp 1 | 55
Muscle Rigidity 1 | 49
Muscular stiffness 1 | 12
Nephritis, Tubulointerstitial 1 | 8
Pancreatic Insufficiency 1 | 13
Peripheral Neuropathy 1 | 134
Photodysphoria 1 | 121
Photophobia 1 | 121
Polydipsia 1 | 15
Polyneuropathy 1 | 64
Polyuria 1 | 23
Progressive neurologic deterioration 1 | 19
Reduced visual acuity 1 | 63
Renal tubular disorder 1 | 12
Retinal Neovascularization 1 | 4
Rickets 1 | 49
Shared Paranoid Disorder 1 | 5
Supratentorial atrophy 1 | 94
X-linked cerebral adrenoleukodystrophy 1 | 116
interstitial lung disease 1 | 298
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Enzyme 8 | 4,145
Non-IDG 1 | 12,091

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 9 | 9
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aspartate aminotransferase, cytoplasmic GOT1 Tbio Enzyme -2.25904 173.1 355
Glutamate--cysteine ligase regulatory subunit GCLM Tbio Enzyme -2.23855 156.3 277
Glutamate--cysteine ligase catalytic subunit GCLC Tchem Enzyme -2.48963 294.6 293
L-lactate dehydrogenase A chain LDHA Tchem Enzyme -3.03454 1030.5 577
Cysteine dioxygenase type 1 CDO1 Tbio Enzyme -1.58332 35.3 90
3-mercaptopyruvate sulfurtransferase MPST Tbio Enzyme -1.85628 72.4 79
Cysteine--tRNA ligase, cytoplasmic CARS Tbio Enzyme -3.00492 954.7 154
Cystinosin CTNS Tbio Non-IDG -2.31471 205.6 165
Cystathionine gamma-lyase CTH Tbio Enzyme -2.70857 467.8 252