Development Level

Tbio 5 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal lens morphology 1 | 81
abnormal sleep behavior 1 | 70
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased urine creatinine lev... 1 | 3
impaired righting response 1 | 26
increased body length 1 | 32
increased bone mineral content 1 | 108
increased lean body mass 1 | 172
increased spleen weight 1 | 10
persistence of hyaloid vascula... 1 | 33
prolonged QRS complex duration 1 | 8
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Carcinoma 7 | 11,493
Atherosclerosis 5 | 291
Autosomal recessive predisposition 5 | 1,442
Hypertension 5 | 396
Hypothyroidism 5 | 122
Kidney disease 5 | 430
diabetes mellitus 5 | 1,728
interstitial cystitis 5 | 2,312
Abdomen distended 4 | 43
Chronic granulomatous disease 4 | 13
Coarse facial features 4 | 108
Cognitive delay 4 | 608
Congenital hypothyroidism 4 | 26
Constipation 4 | 181
Dull intelligence 4 | 645
Dyschezia 4 | 135
Fatigue 4 | 182
Global developmental delay 4 | 608
Goiter 4 | 38
Hypersomnia 4 | 8
Icterus 4 | 82
Intellectual disability 4 | 1,016
Large bregma sutures 4 | 46
Large fontanelle 4 | 46
Large, late-closing fontanelle 4 | 46
Low intelligence 4 | 645
Macroglossia 4 | 65
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Muscle hypotonia 4 | 571
Poor school performance 4 | 645
Short stature 4 | 531
Thickened facial skin with coarse facial features 4 | 108
Thyroid Dyshormonogenesis 1 4 | 6
Umbilical hernia 4 | 93
Wide bregma sutures 4 | 46
psoriasis 4 | 6,694
Astrocytoma, Pilocytic 3 | 3,081
Autoimmune thyroiditis 3 | 27
Cancer 3 | 2,499
Graves' disease 3 | 24
Kidney Failure, Chronic 3 | 46
Kidney cancer 3 | 2,613
Liver Cirrhosis, Experimental 3 | 769
Pendred Syndrome 3 | 22
glioblastoma 3 | 5,792
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
pancreatic cancer 3 | 2,398
Addison's disease 2 | 31
Autoimmune Diseases 2 | 67
Breast cancer 2 | 3,578
Celiac disease 2 | 116
Cerebrovascular disease 2 | 238
Chronic Obstructive Airway Disease 2 | 37
Coronary artery disease 2 | 268
Diabetes Mellitus, Experimental 2 | 108
Eczema 2 | 45
Fever 2 | 138
Heart disease 2 | 306
Heart failure 2 | 162
Hepatomegaly 2 | 285
Hyperpigmented macules 2 | 42
Hyperthyroidism 2 | 53
Infectious disease of lung 2 | 29
Lymphadenitis 2 | 15
Lymphadenopathy 2 | 62
Malabsorption 2 | 82
Melanoma 2 | 711
Multiple pulmonary infections 2 | 29
Neutrophil abnormality 2 | 20
Osteomyelitis due to immunodeficiency 2 | 4
Otitis Media 2 | 52
Paranasal Sinus Diseases 2 | 34
Photosensitivity of skin 2 | 51
Pyloric Stenosis 2 | 47
Recurrent bacterial skin infections 2 | 8
Recurrent pneumonia 2 | 29
Recurrent pulmonary infections 2 | 29
Recurrent respiratory infections 2 | 141
Renal Insufficiency 2 | 90
Sinusitis 2 | 65
Skin cancer 2 | 469
Thyroiditis 2 | 29
Thyrotoxicosis 2 | 38
Tracheoesophageal Fistula 2 | 36
adrenocortical carcinoma 2 | 1,428
cutaneous lupus erythematosus 2 | 1,057
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287
uncontrolled asthma 2 | 56

Tissue

Endocrine System 9 | 18,159
Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Cardiovascular System 7 | 15,192

Target Family

Enzyme 5 | 4,145
Non-IDG 2 | 12,091
Ion Channel 1 | 344
Transporter 1 | 473

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 9 | 9
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b-245 heavy chain CYBB Tchem Ion Channel -3.09698 1276.8 315
Thyroglobulin TG Tbio Non-IDG -3.88676 7423.9 1081
Thyroid peroxidase TPO Tclin Enzyme -2.83776 580.4 368
Dual oxidase 1 DUOX1 Tbio Enzyme -2.50131 279.5 85
Dual oxidase 2 DUOX2 Tchem Enzyme -2.45061 251.8 126
NADPH oxidase 3 NOX3 Tbio Enzyme -1.52922 32.9 139
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.58058 376.0 164
Sodium/iodide cotransporter SLC5A5 Tbio Transporter -3.03414 1016.4 360
NADPH oxidase 4 NOX4 Tchem Enzyme -2.87113 773.1 393