Development Level

Tbio 7 | 11,445
Tclin 4 | 613
Tchem 2 | 1,598

IMPC Phenotype

increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
decreased body length 1 | 101
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased or absent threshold ... 1 | 101
long tibia 1 | 25
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 8 | 11,493
ovarian cancer 8 | 8,520
psoriasis 8 | 6,694
Cancer 7 | 2,499
lung cancer 7 | 4,740
medulloblastoma, large-cell 7 | 6,241
Breast cancer 6 | 3,578
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
lung adenocarcinoma 5 | 2,716
osteosarcoma 5 | 7,950
primitive neuroectodermal tumor 5 | 3,035
Carcinoma, Hepatocellular 4 | 228
Colorectal Neoplasms 4 | 243
Disease Models, Animal 4 | 155
Liver carcinoma 4 | 240
Waldenstrons macroglobulinemia 4 | 765
ductal carcinoma in situ 4 | 1,745
ependymoma 4 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
nasopharyngeal carcinoma 4 | 1,058
non-small cell lung cancer 4 | 2,890
tuberculosis 4 | 2,010
Adenocarcinoma of lung 3 | 142
Adenocarcinoma of pancreas 3 | 14
Astrocytoma, Pilocytic 3 | 3,081
Atrial Fibrillation 3 | 124
Endometriosis 3 | 540
Metastatic Breast Carcinoma 3 | 21
adrenocortical carcinoma 3 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
primary Sjogren syndrome 3 | 735
Acute lymphoid leukemia 2 | 25
Anemia 2 | 365
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Breast Neoplasms 2 | 445
Cerebellar Ataxia 2 | 304
Chronic myeloid leukemia 2 | 12
Diarrhea 2 | 253
Failure to gain weight 2 | 365
Hb SS disease 2 | 2
Hemoglobin SS disease with crisis 2 | 2
Malignant melanoma 2 | 2
Malignant tumor of head and/or neck 2 | 15
Malignant tumor of ovary 2 | 25
Mammary Neoplasms 2 | 425
Multiple myeloma 2 | 1,332
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Xeroderma pigmentosum group D 2 | 33
active Crohn's disease 2 | 922
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis and chronic rhinosinusitis 2 | 214
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
non-small cell lung carcinoma 2 | 317
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
posterior fossa group B ependymoma 2 | 416
relapsing-remitting multiple sclerosis 2 | 18
sonic hedgehog group medulloblastoma 2 | 467
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Abdominal Pain 1 | 98
Adverse reaction to drug 1 | 61
Bone pain 1 | 42
Cachexia 1 | 50
Chronic heart failure 1 | 46
Defective T cell proliferation 1 | 1
Drug-Related Side Effects and Adverse Reactions 1 | 62
Hemolytic anemia 1 | 77
IMMUNODEFICIENCY 24 1 | 1
Immunoglobulin IgG2 deficiency 1 | 3
Immunologic Deficiency Syndromes 1 | 113
Myoclonus 1 | 74
Neoplasm Metastasis 1 | 168
Neoplasm Recurrence, Local 1 | 37
Nervous System Diseases 1 | 53
Neural Tube Defects 1 | 31
Neutropenia 1 | 72
Opsoclonus 1 | 5
Ovarian Neoplasms 1 | 102
Progressive neurologic deterioration 1 | 19
Squamous cell carcinoma 1 | 129
nervous system disorder 1 | 53
ovarian neoplasm 1 | 99
sarcoidosis 1 | 370

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192
Nervous System 12 | 16,725
Respiratory system 12 | 16,393

Target Family

Enzyme 7 | 4,145
Kinase 3 | 634
Transporter 3 | 473

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 13 | 13
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CTP synthase 1 CTPS1 Tbio Enzyme -2.29349 196.5 107
Thymidylate synthase TYMS Tclin Enzyme -2.93426 732.0 733
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
Sodium/nucleoside cotransporter 1 SLC28A1 Tbio Transporter -1.94286 85.5 41
Deoxycytidylate deaminase DCTD Tbio Enzyme -1.82599 65.4 147
Solute carrier family 28 member 3 SLC28A3 Tchem Transporter -1.73893 55.0 28
Deoxycytidine kinase DCK Tchem Kinase -2.63558 455.4 434
Equilibrative nucleoside transporter 1 SLC29A1 Tclin Transporter -2.61544 427.2 413
Ribonucleoside-diphosphate reductase subunit M2 B RRM2B Tbio Enzyme -1.91697 95.0 244
UMP-CMP kinase CMPK1 Tbio Kinase -1.97755 96.3 322