Development Level

Tbio 6 | 11,445
Tchem 6 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
decreased circulating HDL chol... 1 | 68
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134

Disease

Carcinoma 13 | 11,493
ovarian cancer 12 | 8,520
Cancer 11 | 2,499
glioblastoma 10 | 5,792
lung cancer 10 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung adenocarcinoma 9 | 2,716
psoriasis 9 | 6,694
atypical teratoid / rhabdoid tumor 8 | 5,112
Astrocytoma, Pilocytic 7 | 3,081
Prostatic Neoplasms 7 | 495
active Crohn's disease 7 | 922
astrocytoma 7 | 1,146
ependymoma 7 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
non-small cell lung cancer 7 | 2,890
osteosarcoma 7 | 7,950
pancreatic cancer 7 | 2,398
ulcerative colitis 7 | 1,819
Breast cancer 6 | 3,578
Rheumatoid arthritis 6 | 1,191
adult high grade glioma 6 | 3,801
diabetes mellitus 6 | 1,728
group 3 medulloblastoma 6 | 4,104
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
medulloblastoma, large-cell 6 | 6,241
Arthritis, Rheumatoid 5 | 174
Breast Neoplasms 5 | 445
Carcinoma, Hepatocellular 5 | 228
Diarrhea 5 | 253
Kidney cancer 5 | 2,613
Liver carcinoma 5 | 240
Liver disease 5 | 237
Mammary Neoplasms 5 | 425
Multiple myeloma 5 | 1,332
Schizophrenia 5 | 1,160
esophageal adenocarcinoma 5 | 737
Asthma 4 | 385
Coronary artery disease 4 | 268
Hypertension 4 | 396
Kidney disease 4 | 430
Neutropenia 4 | 72
adrenocortical carcinoma 4 | 1,428
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
malignant mesothelioma 4 | 3,232
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Adverse reaction to drug 3 | 61
Alzheimer's disease 3 | 658
Arthritis 3 | 290
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Cerebrovascular disease 3 | 238
Chemical and Drug Induced Liver Injury 3 | 195
Colorectal Neoplasms 3 | 243
Common cold 3 | 67
Drug-Related Side Effects and Adverse Reactions 3 | 62
Esophageal Neoplasms 3 | 69
Kidney Diseases 3 | 114
Liver Cirrhosis, Experimental 3 | 769
Major Depressive Disorder 3 | 301
Myocardial Infarction 3 | 151
Neoplasm Metastasis 3 | 168
Pain agnosia 3 | 104
Pleurisy 3 | 19
Reperfusion Injury 3 | 86
Toxic encephalopathy 3 | 141
Urticaria 3 | 67
Waldenstrons macroglobulinemia 3 | 765
dermatomyositis 3 | 966
lung carcinoma 3 | 2,843
non primary Sjogren syndrome sicca 3 | 891
oligodendroglioma 3 | 2,850
pediatric high grade glioma 3 | 1,064
primitive neuroectodermal tumor 3 | 3,035
Acute kidney injury 2 | 70
Ankylosing spondylitis 2 | 140
Barrett's esophagus 2 | 182
Bilirubin metabolic disorder 2 | 41
Brain Injuries 2 | 65
Diabetes Mellitus, Experimental 2 | 108
Esophageal Squamous Cell Carcinoma 2 | 77
Fever 2 | 138
Glioma 2 | 74
Gout 2 | 106
Heart failure 2 | 162
Hyperalgesia 2 | 83
Inflammation 2 | 120
Kidney Neoplasm 2 | 29
Kidney Neoplasms 2 | 37
Lung diseases 2 | 50
Nervous System Diseases 2 | 53
Squamous cell carcinoma of esophagus 2 | 77
nervous system disorder 2 | 53
non-small cell lung carcinoma 2 | 317
pulmonary tuberculosis 2 | 9

Tissue

Blood and immune system 18 | 16,909
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Cardiovascular System 16 | 15,192

Target Family

Enzyme 12 | 4,145
Non-IDG 4 | 12,091
Transporter 2 | 473

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 18 | 18
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA topoisomerase 2-alpha TOP2A Tclin Enzyme -2.88264 723.0 847
Canalicular multispecific organic anion transporter 2 ABCC3 Tbio Transporter -2.46032 287.4 214
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.23035 1641.3 479
UDP-glucuronosyltransferase 1-1 UGT1A1 Tchem Enzyme -2.95436 932.5 146
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731
Multidrug resistance protein 1 ABCB1 Tchem Transporter -3.61827 4039.4 875