Development Level

Tchem 10 | 1,598
Tbio 7 | 11,445
Tclin 4 | 613
Tdark 1 | 6,588

IMPC Phenotype

increased circulating HDL chol... 2 | 80
increased total body fat amoun... 2 | 134
preweaning lethality, complete... 2 | 979
abnormal sleep behavior 1 | 70
decreased circulating HDL chol... 1 | 68
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased startle reflex 1 | 112

Disease

Carcinoma 17 | 11,493
Cancer 12 | 2,499
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
ovarian cancer 11 | 8,520
psoriasis 11 | 6,694
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
Adverse reaction to drug 9 | 61
Drug-Related Side Effects and Adverse Reactions 9 | 62
active Crohn's disease 9 | 922
lung cancer 9 | 4,740
non-small cell lung cancer 9 | 2,890
lung adenocarcinoma 8 | 2,716
osteosarcoma 8 | 7,950
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
Astrocytoma, Pilocytic 6 | 3,081
Breast Neoplasms 6 | 445
Kidney cancer 6 | 2,613
Mammary Neoplasms 6 | 425
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
Breast cancer 5 | 3,578
Chemical and Drug Induced Liver Injury 5 | 195
Liver disease 5 | 237
Neutropenia 5 | 72
Rheumatoid arthritis 5 | 1,191
astrocytoma 5 | 1,146
cutaneous lupus erythematosus 5 | 1,057
malignant mesothelioma 5 | 3,232
ulcerative colitis 5 | 1,819
Autosomal recessive predisposition 4 | 1,442
Bilirubin metabolic disorder 4 | 41
Carcinoma, squamous cell of head and neck 4 | 31
Colorectal Neoplasms 4 | 243
Diarrhea 4 | 253
Multiple myeloma 4 | 1,332
Prostatic Neoplasms 4 | 495
Squamous cell carcinoma of the head and neck 4 | 29
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
diabetes mellitus 4 | 1,728
group 3 medulloblastoma 4 | 4,104
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
pancreatic cancer 4 | 2,398
Arthritis, Rheumatoid 3 | 174
Bipolar Disorder 3 | 666
Carcinoma, Hepatocellular 3 | 228
Cholestasis 3 | 155
Cocaine-Related Disorders 3 | 92
Epilepsy 3 | 792
Hypertension 3 | 396
Icterus 3 | 82
Liver Cirrhosis, Experimental 3 | 769
Liver carcinoma 3 | 240
Nervous System Diseases 3 | 53
Neurotoxicity Syndromes 3 | 26
Obesity 3 | 678
Schizophrenia 3 | 1,160
Sickle Cell Anemia 3 | 53
Toxic encephalopathy 3 | 141
colon cancer 3 | 1,478
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
nervous system disorder 3 | 53
non primary Sjogren syndrome sicca 3 | 891
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Acute kidney injury 2 | 70
Alopecia 2 | 115
Alzheimer's disease 2 | 658
Anemia 2 | 365
Attention deficit hyperactivity disorder 2 | 278
Becker muscular dystrophy 2 | 191
Disease Progression 2 | 136
Esophageal Squamous Cell Carcinoma 2 | 77
Gout 2 | 106
Kidney disease 2 | 430
Liver cancer 2 | 604
Multiple Sclerosis 2 | 540
Myopathy 2 | 185
Neonatal Jaundice 2 | 30
Neoplasm Metastasis 2 | 168
Neuroblastoma 2 | 80
Parkinson's disease 2 | 392
Seizures 2 | 596
Squamous cell carcinoma of esophagus 2 | 77
active ulcerative colitis 2 | 764
adrenocortical adenoma 2 | 131
adrenocortical carcinoma 2 | 1,428
dermatomyositis 2 | 966
drug-induced hepatitis 2 | 44
esophageal adenocarcinoma 2 | 737
medulloblastoma 2 | 720
non-small cell lung carcinoma 2 | 317
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972

Tissue

Liver and Pancreas 22 | 16,750
Urinary Tract 22 | 16,678
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Male tissues 21 | 17,142
Skin and soft tissues 21 | 17,230
Blood and immune system 20 | 16,909
Nervous System 19 | 16,725
Respiratory system 18 | 16,393
Cardiovascular System 16 | 15,192

Target Family

Enzyme 13 | 4,145
Transporter 5 | 473
Non-IDG 4 | 12,091

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 22 | 22
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.61701 4015.4 248
Multidrug resistance protein 1 ABCB1 Tchem Transporter -3.61827 4039.4 875
UDP-glucuronosyltransferase 1-1 UGT1A1 Tchem Enzyme -2.95436 932.5 146
Canalicular multispecific organic anion transporter 1 ABCC2 Tchem Transporter -2.90204 834.9 234
Multidrug resistance-associated protein 1 ABCC1 Tchem Transporter -2.81072 662.2 328
Cytochrome P450 3A4 CYP3A4 Tclin Enzyme -3.65839 4688.0 397
Protein disulfide-isomerase A2 PDIA2 Tbio Enzyme -1.65060 45.7 295
Solute carrier organic anion transporter family member 1B1 SLCO1B1 Tchem Transporter -2.77788 574.0 124
Stromal cell-derived factor 2-like protein 1 SDF2L1 Tdark Non-IDG -0.57145 4.35 62
ATP-binding cassette sub-family G member 2 ABCG2 Tchem Transporter -3.41877 2731.1 246