Development Level

Tbio 9 | 11,445
Tchem 7 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

IMPC Phenotype

increased circulating HDL chol... 2 | 80
preweaning lethality, complete... 2 | 979
decreased circulating HDL chol... 1 | 68
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134

Disease

Carcinoma 15 | 11,493
Cancer 10 | 2,499
ovarian cancer 10 | 8,520
psoriasis 10 | 6,694
glioblastoma 9 | 5,792
osteosarcoma 8 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Astrocytoma, Pilocytic 6 | 3,081
Chemical and Drug Induced Liver Injury 6 | 195
Liver disease 6 | 237
active Crohn's disease 6 | 922
adult high grade glioma 6 | 3,801
astrocytoma 6 | 1,146
atypical teratoid / rhabdoid tumor 6 | 5,112
diabetes mellitus 6 | 1,728
ependymoma 6 | 4,679
lung adenocarcinoma 6 | 2,716
pancreatic cancer 6 | 2,398
Prostatic Neoplasms 5 | 495
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
lung cancer 5 | 4,740
medulloblastoma, large-cell 5 | 6,241
ulcerative colitis 5 | 1,819
Acute kidney injury 4 | 70
Breast cancer 4 | 3,578
Cholestasis 4 | 155
Coronary artery disease 4 | 268
Diarrhea 4 | 253
Drug-Related Side Effects and Adverse Reactions 4 | 62
Epilepsy 4 | 792
Gout 4 | 106
Kidney disease 4 | 430
Multiple myeloma 4 | 1,332
Pain agnosia 4 | 104
Schizophrenia 4 | 1,160
Sickle Cell Anemia 4 | 53
invasive ductal carcinoma 4 | 2,951
non primary Sjogren syndrome sicca 4 | 891
non-small cell lung cancer 4 | 2,890
Adverse reaction to drug 3 | 61
Anemia 3 | 365
Articular gout 3 | 11
Autosomal recessive predisposition 3 | 1,442
Bilirubin metabolic disorder 3 | 41
Breast Neoplasms 3 | 445
Carcinoma, Hepatocellular 3 | 228
Cerebrovascular disease 3 | 238
Hypertension 3 | 396
Kidney Failure, Chronic 3 | 46
Liver Cirrhosis, Experimental 3 | 769
Liver carcinoma 3 | 240
Major Depressive Disorder 3 | 301
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Myocardial Infarction 3 | 151
Nervous System Diseases 3 | 53
Pericholangitis 3 | 8
Rheumatoid arthritis 3 | 1,191
Toxic encephalopathy 3 | 141
Unipolar Depression 3 | 250
cutaneous lupus erythematosus 3 | 1,057
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung carcinoma 3 | 2,843
nervous system disorder 3 | 53
pediatric high grade glioma 3 | 1,064
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Actinic keratosis 2 | 21
Ankylosing spondylitis 2 | 140
Bladder Neoplasm 2 | 112
Cardiomyopathies 2 | 110
Common cold 2 | 67
Drug Hypersensitivity 2 | 34
Drug allergy 2 | 36
Esophageal Neoplasms 2 | 69
Esophageal Squamous Cell Carcinoma 2 | 77
Esophagitis 2 | 35
Fever 2 | 138
Gastritis 2 | 47
Gastroesophageal reflux disease 2 | 110
Heart failure 2 | 162
Hyperalgesia 2 | 83
Hyperuricemia 2 | 49
Juvenile rheumatoid arthritis 2 | 111
Kidney Diseases 2 | 114
Menorrhagia 2 | 25
Neoplasm Metastasis 2 | 168
Neutropenia 2 | 72
Osteoarthritis 2 | 184
Pain 2 | 103
Parkinson's disease 2 | 392
Squamous cell carcinoma of esophagus 2 | 77
Synovitis 2 | 78
Urinary Bladder Neoplasms 2 | 114
adrenocortical adenoma 2 | 131
pulmonary tuberculosis 2 | 9

Tissue

Digestive Tract 22 | 17,369
Urinary Tract 21 | 16,678
Liver and Pancreas 20 | 16,750
Skin and soft tissues 20 | 17,230
Male tissues 19 | 17,142
Female tissues 17 | 17,400
Blood and immune system 16 | 16,909
Endocrine System 16 | 18,159
Nervous System 16 | 16,725
Respiratory system 15 | 16,393
Cardiovascular System 12 | 15,192

Target Family

Enzyme 13 | 4,145
Non-IDG 7 | 12,091
Transporter 2 | 473

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 22 | 22
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UDP-glucuronosyltransferase 2B7 UGT2B7 Tchem Enzyme -2.31570 219.0 131
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.23035 1641.3 479
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731
Cytochrome P450 2C8 CYP2C8 Tchem Non-IDG -2.55207 348.9 159
Cytochrome P450 2C19 CYP2C19 Tchem Non-IDG -3.22652 1740.4 154
UDP-glucuronosyltransferase 1-3 UGT1A3 Tbio Enzyme -1.83933 63.3 13
UDP-glucuronosyltransferase 1-1 UGT1A1 Tchem Enzyme -2.95436 932.5 146
Protein disulfide-isomerase A2 PDIA2 Tbio Enzyme -1.65060 45.7 295
Cytochrome P450 3A4 CYP3A4 Tclin Enzyme -3.65839 4688.0 397
Solute carrier family 22 member 8 SLC22A8 Tclin Transporter -2.40126 258.4 113