Development Level

Tbio 12 | 11,445
Tchem 7 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal hair growth 1 | 10
decreased circulating alanine ... 1 | 47
decreased circulating glucose ... 1 | 126
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 15 | 11,493
ovarian cancer 13 | 8,520
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
medulloblastoma, large-cell 8 | 6,241
Astrocytoma, Pilocytic 7 | 3,081
glioblastoma 7 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
osteosarcoma 7 | 7,950
Breast cancer 6 | 3,578
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
psoriasis 6 | 6,694
group 3 medulloblastoma 5 | 4,104
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
pancreatic cancer 5 | 2,398
primary pancreatic ductal adenocarcinoma 5 | 1,109
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Epilepsy 4 | 792
Gaucher's disease 4 | 26
Seizures 4 | 596
adult high grade glioma 4 | 3,801
aldosterone-producing adenoma 4 | 665
astrocytic glioma 4 | 2,597
ependymoma 4 | 4,679
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
pituitary cancer 4 | 1,972
Alzheimer's disease 3 | 658
Autosomal recessive predisposition 3 | 1,442
Cancer 3 | 2,499
Down syndrome 3 | 499
Krabbe disease 3 | 12
Liver Cirrhosis, Experimental 3 | 769
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Neuropathy 3 | 261
Optic Atrophy 3 | 242
Pick disease 3 | 1,894
active ulcerative colitis 3 | 764
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
mucosa-associated lymphoid tissue lymphoma 3 | 484
progressive supranuclear palsy 3 | 676
Abdominal Pain 2 | 98
Amyotrophic lateral sclerosis 2 | 451
Anemia 2 | 365
Atopic dermatitis 2 | 952
Cerebellar Ataxia 2 | 304
Cerebrospinal fluid protein increased above normal 2 | 14
Congenital deafness 2 | 185
Congenital pes cavus 2 | 88
Deafness 2 | 198
Decreased tendon reflex 2 | 122
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Distal sensory impairment 2 | 52
Distal sensory impairment of all modalities 2 | 7
Dystonia 2 | 164
Dystonic disease 2 | 106
Failure to gain weight 2 | 365
Fatigue 2 | 182
Gait abnormality 2 | 135
Gangliosidosis 2 | 20
Hearing Loss, Partial 2 | 185
Hemoglobin low 2 | 124
Hereditary Sensory Autonomic Neuropathy, Type 1 2 | 4
Hydrocephalus 2 | 152
Hyperreflexia 2 | 209
Leukodystrophy 2 | 55
Metachromatic leukodystrophy 2 | 14
Muscle Hypertonia 2 | 88
Neurodegenerative disease 2 | 414
Pediatric failure to thrive 2 | 365
Peripheral demyelination 2 | 16
Peripheral sensorimotor neuropathy 2 | 16
Rheumatoid arthritis 2 | 1,191
Short stature 2 | 531
Vomiting 2 | 116
active Crohn's disease 2 | 922
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
hearing impairment 2 | 199
inclusion-cell disease 2 | 16
interstitial cystitis 2 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 20 | 16,909
Digestive Tract 20 | 17,369
Liver and Pancreas 20 | 16,750
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Male tissues 19 | 17,142
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Cardiovascular System 18 | 15,192
Nervous System 18 | 16,725
Respiratory system 18 | 16,393

Target Family

Enzyme 19 | 4,145
Kinase 2 | 634

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 21 | 21
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Galactocerebrosidase GALC Tbio Enzyme -2.56924 363.2 143
Alkaline ceramidase 3 ACER3 Tbio Enzyme -2.07938 117.1 95
Sphingosine-1-phosphate phosphatase 2 SGPP2 Tbio Enzyme -0.72925 6.15 77
Phosphatidylcholine:ceramide cholinephosphotransferase 1 SGMS1 Tchem Enzyme -1.61164 41.6 0
3-ketodihydrosphingosine reductase KDSR Tbio Enzyme -1.21646 15.3 101
Sialidase-3 NEU3 Tbio Enzyme -2.02704 118.2 35
2-hydroxyacylsphingosine 1-beta-galactosyltransferase UGT8 Tbio Enzyme -1.67729 39.6 148
Alpha-galactosidase A GLA Tclin Enzyme -3.00418 985.0 249
Ceramide glucosyltransferase UGCG Tclin Enzyme -2.17676 128.8 135
Serine palmitoyltransferase 1 SPTLC1 Tchem Enzyme -2.16711 143.2 285