Development Level

Tbio 5 | 11,445
Tclin 3 | 613
Tchem 1 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal epididymis morphology 1 | 42
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
abnormal stomach morphology 1 | 10
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
increased vertical activity 1 | 24

Disease

Carcinoma 9 | 11,493
ovarian cancer 7 | 8,520
Autosomal recessive predisposition 6 | 1,442
glioblastoma 6 | 5,792
group 3 medulloblastoma 6 | 4,104
lung cancer 6 | 4,740
psoriasis 6 | 6,694
atypical teratoid / rhabdoid tumor 5 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primitive neuroectodermal tumor 5 | 3,035
Autistic Disorder 4 | 364
Cognitive delay 4 | 608
Epilepsy 4 | 792
Global developmental delay 4 | 608
Intellectual disability 4 | 1,016
Liver Cirrhosis, Experimental 4 | 769
Mental and motor retardation 4 | 608
Seizures 4 | 596
Succinic semialdehyde dehydrogenase deficiency 4 | 16
adult high grade glioma 4 | 3,801
colon cancer 4 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
nephrosclerosis 4 | 333
Astrocytoma, Pilocytic 3 | 3,081
Bipolar Disorder 3 | 666
Dull intelligence 3 | 645
Highly variable clinical phenotype 3 | 150
Highly variable phenotype and severity 3 | 150
Highly variable phenotype, even within families 3 | 150
Lethargy 3 | 77
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Muscle hypotonia 3 | 571
Phenotypic variability 3 | 150
Poor school performance 3 | 645
Small head 3 | 374
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
fibroadenoma 3 | 559
invasive ductal carcinoma 3 | 2,951
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
ulcerative colitis 3 | 1,819
Abnormally small eyeball 2 | 97
Alcoholic Intoxication, Chronic 2 | 289
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Colorectal Neoplasms 2 | 243
Congenital anomaly of face 2 | 56
Decreased size of eyeball 2 | 97
Delayed speech and language development 2 | 112
Depressive disorder 2 | 409
Distortion of face 2 | 46
Downward slant of palpebral fissure 2 | 158
Dysmorphic facies 2 | 46
Dystonia 2 | 164
Dystonic disease 2 | 106
Funny looking face 2 | 46
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hyperreflexia 2 | 209
Infantile onset 2 | 238
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Language Delay 2 | 112
Microphthalmos 2 | 100
Orotic aciduria 2 | 18
Pick disease 2 | 1,894
Poor growth 2 | 114
Schizophrenia 2 | 1,160
Short nose 2 | 132
Small nose 2 | 132
Speech Delay 2 | 112
Speech impairment 2 | 112
Very poor growth 2 | 114
West Syndrome 2 | 28
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
chronic lymphosyte leukemia 2 | 204
chronic rhinosinusitis 2 | 512
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
facial deformity 2 | 46
interstitial cystitis 2 | 2,312
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Respiratory system 8 | 16,393
Cardiovascular System 7 | 15,192

Target Family

Enzyme 9 | 4,145

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 9 | 9
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dihydropyrimidine dehydrogenase [NADP(+)] DPYD Tclin Enzyme -2.62432 395.0 159
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 Tbio Enzyme -1.18866 15.6 381
Beta-ureidopropionase UPB1 Tbio Enzyme -1.65421 45.7 60
4-aminobutyrate aminotransferase, mitochondrial ABAT Tclin Enzyme -2.02391 104.3 204
Membrane primary amine oxidase AOC3 Tchem Enzyme -2.79843 685.2 285
Dihydropyrimidinase DPYS Tbio Enzyme -1.82904 65.0 194
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.97865 1004.9 470
Beta-Ala-His dipeptidase CNDP1 Tbio Enzyme -1.89853 81.0 255
Glutamate decarboxylase 1 GAD1 Tbio Enzyme -2.96960 896.3 529