Development Level

Tbio 6 | 11,445

IMPC Phenotype

decreased mean corpuscular vol... 2 | 79
abnormal behavior 1 | 298
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
cataract 1 | 92
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
enlarged heart 1 | 210
hypoactivity 1 | 132
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134

Disease

Carcinoma 5 | 11,493
Peroxisomal disease 5 | 22
Adrenoleukodystrophy 4 | 29
Atopic dermatitis 3 | 952
ductal carcinoma in situ 3 | 1,745
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
psoriasis 3 | 6,694
Abnormal skeletal development 2 | 60
Abnormality of retinal pigmentation 2 | 111
Autosomal recessive predisposition 2 | 1,442
Dry skin 2 | 75
Epilepsy 2 | 792
Ichthyoses 2 | 41
Osteochondrodysplasias 2 | 72
Peripheral Neuropathy 2 | 134
Pyramidal sign 2 | 29
Refsum disease 2 | 20
Retinal Diseases 2 | 55
Retinal pigment epithelial abnormality 2 | 111
Seizures 2 | 596
Xerosis 2 | 75
astrocytic glioma 2 | 2,597
glioblastoma 2 | 5,792
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Abnormal coordination 1 | 15
Abnormal vision 1 | 52
Abnormality of epiphysis morphology 1 | 39
Abnormality of metabolism/homeostasis 1 | 134
Abnormality of the skeletal system 1 | 11
Ataxia, Appendicular 1 | 25
Ataxia, Truncal 1 | 21
Beriberi 1 | 12
Bulbar palsy 1 | 19
Bulbar weakness 1 | 19
Cardiac Arrhythmia 1 | 103
Cardiac conduction abnormalities 1 | 78
Cardiomegaly 1 | 116
Cardiomyopathies 1 | 110
Central nervous system demyelination 1 | 28
Cerebrospinal fluid protein increased above normal 1 | 14
Chemical and Drug Induced Liver Injury 1 | 195
Colorectal Neoplasms 1 | 243
Conduction disorder of the heart 1 | 79
Congenital deafness 1 | 185
Congestive heart failure 1 | 113
Corneal erosion 1 | 16
Cortical white matter abnormalities seen on MRI 1 | 18
Deafness 1 | 198
Defective enamel matrix 1 | 35
Dental Enamel Hypoplasia 1 | 43
Difficulties with night vision 1 | 87
Dysplasia of tooth enamel 1 | 35
EKG abnormalities 1 | 78
Electrocardiogram abnormal 1 | 81
Electrocardiogram change 1 | 78
Elevated levels of phytanic acid 1 | 15
Erectile dysfunction 1 | 32
Erythema 1 | 58
Fibrosis 1 | 44
Flushing 1 | 60
Gaucher disease type 1 1 | 180
Generalized hyperpigmentation 1 | 22
Hammer Toe 1 | 23
Hearing Loss, Partial 1 | 185
Heart failure 1 | 162
Hemiplegia and hemiparesis 1 | 38
Hyperkeratosis 1 | 50
Hyperkyphosis 1 | 111
Hyperpigmentation 1 | 37
Hypesthesia 1 | 7
Kyphosis deformity of spine 1 | 114
Leber congenital amaurosis 1 | 69
Leukoaraiosis 1 | 18
Loss of speech 1 | 16
Lymphoma 1 | 81
Macular degeneration 1 | 65
Muscle weakness of limb 1 | 21
Nail dysplasia 1 | 52
Nerve Degeneration 1 | 121
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Paraparesis 1 | 6
Photodysphoria 1 | 121
Photophobia 1 | 121
Polyneuropathy 1 | 64
Rhizomelic chondrodysplasia punctata 1 | 11
Sengers syndrome 1 | 18
Sphincter disturbances 1 | 16
Succinic semialdehyde dehydrogenase deficiency 1 | 16
Thin dental enamel 1 | 35
Urinary Incontinence 1 | 50
X- linked recessive 1 | 110
X-linked cerebral adrenoleukodystrophy 1 | 116
hearing impairment 1 | 199

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Cardiovascular System 5 | 15,192

Target Family

Enzyme 3 | 4,145
Transporter 3 | 473

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 6 | 6
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Very long-chain acyl-CoA synthetase SLC27A2 Tbio Transporter -1.73251 54.7 121
2-hydroxyacyl-CoA lyase 1 HACL1 Tbio Enzyme -1.82472 63.8 159
Fatty aldehyde dehydrogenase ALDH3A2 Tbio Enzyme -2.29743 197.2 311
Phytanoyl-CoA dioxygenase, peroxisomal PHYH Tbio Enzyme -2.34936 221.5 300
ATP-binding cassette sub-family D member 1 ABCD1 Tbio Transporter -2.06857 127.3 269
ATP-binding cassette sub-family D member 2 ABCD2 Tbio Transporter -1.65079 43.1 185