Development Level

Tbio 10 | 11,445
Tclin 7 | 613
Tchem 6 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased pulmonary respirator... 1 | 5
decreased vertical activity 1 | 208
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased cardiac muscle contr... 1 | 8
increased circulating alanine ... 1 | 13
increased circulating sodium l... 1 | 71
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 18 | 11,493
psoriasis 13 | 6,694
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Alcoholic Intoxication, Chronic 8 | 289
lung cancer 8 | 4,740
osteosarcoma 8 | 7,950
Alcohol dependence 7 | 107
Cancer 7 | 2,499
Schizophrenia 7 | 1,160
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung adenocarcinoma 7 | 2,716
lung carcinoma 7 | 2,843
malignant mesothelioma 7 | 3,232
non-small cell lung cancer 7 | 2,890
ovarian cancer 7 | 8,520
Autosomal recessive predisposition 6 | 1,442
Bipolar Disorder 6 | 666
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
medulloblastoma, large-cell 6 | 6,241
Hypertension 5 | 396
Liver disease 5 | 237
Major Depressive Disorder 5 | 301
Parkinson's disease 5 | 392
Substance abuse 5 | 59
Unipolar Depression 5 | 250
adrenocortical carcinoma 5 | 1,428
aldosterone-producing adenoma 5 | 665
atypical teratoid / rhabdoid tumor 5 | 5,112
fibroadenoma 5 | 559
glioblastoma 5 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
ulcerative colitis 5 | 1,819
Alcohol abuse 4 | 50
Alcoholism 4 | 45
Attention deficit hyperactivity disorder 4 | 278
Autistic Disorder 4 | 364
Breast cancer 4 | 3,578
Depressive disorder 4 | 409
Liver Cirrhosis, Experimental 4 | 769
Pheochromocytoma 4 | 24
Psychotic Disorders 4 | 151
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
esophageal adenocarcinoma 4 | 737
interstitial cystitis 4 | 2,312
nasopharyngeal carcinoma 4 | 1,058
nephrosclerosis 4 | 333
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
Atopic dermatitis 3 | 952
Blepharoptosis 3 | 231
Breast Neoplasms 3 | 445
Chemical and Drug Induced Liver Injury 3 | 195
Cocaine Dependence 3 | 51
Endometriosis 3 | 540
Heroin dependence 3 | 30
Hypotension 3 | 82
Kidney disease 3 | 430
Liver carcinoma 3 | 240
Mammary Neoplasms 3 | 425
Mental Depression 3 | 333
Mental disorders 3 | 12
Mood Disorders 3 | 184
Obesity 3 | 678
Parkinson Disease 3 | 64
Prostatic Neoplasms 3 | 495
Tyrosinemia 3 | 10
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung carcinoma 3 | 317
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
substance-related disorder 3 | 162
tuberculosis 3 | 2,010
Alzheimer's disease 2 | 658
Atherosclerosis 2 | 291
Carcinoma, Hepatocellular 2 | 228
Cholestasis 2 | 155
Cognition Disorders 2 | 32
Colitis 2 | 54
Coronary artery disease 2 | 268
Dementia 2 | 175
Hepatomegaly 2 | 285
Hypoglycemia 2 | 152
Malaria 2 | 160
Melanoma 2 | 711
Neoplasm Invasiveness 2 | 161
Ptosis 2 | 48
Seizures 2 | 596
Toxic encephalopathy 2 | 141
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
adrenocortical adenoma 2 | 131
hepatocellular carcinoma 2 | 547

Tissue

Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Skin and soft tissues 23 | 17,230
Blood and immune system 22 | 16,909
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Respiratory system 22 | 16,393
Urinary Tract 22 | 16,678
Digestive Tract 21 | 17,369
Nervous System 21 | 16,725
Cardiovascular System 20 | 15,192

Target Family

Enzyme 21 | 4,145
Non-IDG 2 | 12,091

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 23 | 23
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 Tbio Enzyme -1.48800 26.8 73
Fumarylacetoacetase FAH Tbio Enzyme -2.39887 253.3 196
Maleylacetoacetate isomerase GSTZ1 Tbio Enzyme -1.99892 99.5 150
Phenylethanolamine N-methyltransferase PNMT Tchem Enzyme -2.90323 857.6 277
Tyrosinase TYR Tclin Enzyme -3.32888 2021.2 494
Aromatic-L-amino-acid decarboxylase DDC Tclin Enzyme -2.78263 593.3 412
Homogentisate 1,2-dioxygenase HGD Tbio Enzyme -2.62003 404.9 159
Catechol O-methyltransferase COMT Tclin Enzyme -3.46304 2976.1 433
Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 Tbio Enzyme -2.25828 174.5 264
Amiloride-sensitive amine oxidase [copper-containing] AOC1 Tchem Enzyme -2.77629 590.0 271