Development Level

Tbio 22 | 11,445
Tclin 13 | 613
Tchem 11 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

embryonic lethality prior to o... 4 | 239
preweaning lethality, complete... 4 | 979
decreased prepulse inhibition 2 | 82
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal retinal vasculature m... 1 | 27
decreased body length 1 | 101
decreased circulating glucose ... 1 | 126
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
limb grasping 1 | 41
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 31 | 11,493
ovarian cancer 30 | 8,520
medulloblastoma, large-cell 27 | 6,241
lung cancer 24 | 4,740
osteosarcoma 23 | 7,950
ependymoma 21 | 4,679
glioblastoma 21 | 5,792
psoriasis 20 | 6,694
atypical teratoid / rhabdoid tumor 19 | 5,112
Breast cancer 16 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
adult high grade glioma 13 | 3,801
non-small cell lung cancer 13 | 2,890
Astrocytoma, Pilocytic 12 | 3,081
Cancer 12 | 2,499
group 3 medulloblastoma 12 | 4,104
primitive neuroectodermal tumor 12 | 3,035
Autosomal recessive predisposition 11 | 1,442
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
lung adenocarcinoma 11 | 2,716
malignant mesothelioma 11 | 3,232
oligodendroglioma 11 | 2,850
pancreatic cancer 11 | 2,398
tuberculosis 11 | 2,010
Kidney cancer 10 | 2,613
Pick disease 10 | 1,894
astrocytic glioma 10 | 2,597
colon cancer 10 | 1,478
interstitial cystitis 10 | 2,312
lung carcinoma 10 | 2,843
group 4 medulloblastoma 9 | 1,855
invasive ductal carcinoma 8 | 2,951
nasopharyngeal carcinoma 8 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Intellectual disability 7 | 1,016
Multiple myeloma 7 | 1,332
Muscle hypotonia 7 | 571
diabetes mellitus 7 | 1,728
pediatric high grade glioma 7 | 1,064
Atopic dermatitis 6 | 952
Dull intelligence 6 | 645
Epilepsy 6 | 792
Lesch-Nyhan syndrome 6 | 12
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
Purine nucleoside phosphorylase deficiency 6 | 11
Schizophrenia 6 | 1,160
ductal carcinoma in situ 6 | 1,745
ulcerative colitis 6 | 1,819
Melanoma 5 | 711
Mental Depression 5 | 333
Seizures 5 | 596
Waldenstrons macroglobulinemia 5 | 765
active Crohn's disease 5 | 922
acute quadriplegic myopathy 5 | 1,158
cutaneous lupus erythematosus 5 | 1,057
cystic fibrosis 5 | 1,696
non primary Sjogren syndrome sicca 5 | 891
primary pancreatic ductal adenocarcinoma 5 | 1,109
Anteverted nostril 4 | 191
Arthritis, Rheumatoid 4 | 174
Atrial Fibrillation 4 | 124
Autistic Disorder 4 | 364
Chronic heart failure 4 | 46
Colorectal Neoplasms 4 | 243
Disease Models, Animal 4 | 155
Endometriosis 4 | 540
Failure to gain weight 4 | 365
Hyperuricemia 4 | 49
Nystagmus 4 | 317
Optic Atrophy 4 | 242
Pediatric failure to thrive 4 | 365
Rheumatoid arthritis 4 | 1,191
Xanthinuria 4 | 10
active ulcerative colitis 4 | 764
acute myeloid leukemia 4 | 783
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
chronic rhinosinusitis 4 | 512
gastric carcinoma 4 | 807
hepatocellular carcinoma 4 | 547
pancreatic carcinoma 4 | 562
pituitary cancer 4 | 1,972
primary Sjogren syndrome 4 | 735
subependymal giant cell astrocytoma 4 | 2,287
Bipolar Disorder 3 | 666
Depressive disorder 3 | 409
Language Delay 3 | 112
Nephrolithiasis 3 | 56
Prostatic Neoplasms 3 | 495
Speech Delay 3 | 112
Speech impairment 3 | 112
Vascular disease 3 | 319
aldosterone-producing adenoma 3 | 665
dermatomyositis 3 | 966
gastric cancer 3 | 459

Tissue

Endocrine System 47 | 18,159
Blood and immune system 46 | 16,909
Digestive Tract 46 | 17,369
Female tissues 46 | 17,400
Liver and Pancreas 46 | 16,750
Male tissues 46 | 17,142
Respiratory system 46 | 16,393
Skin and soft tissues 46 | 17,230
Urinary Tract 46 | 16,678
Cardiovascular System 42 | 15,192
Nervous System 42 | 16,725

Target Family

Enzyme 31 | 4,145
Kinase 6 | 634
Transporter 6 | 473
Non-IDG 4 | 12,091

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine deaminase GDA Tbio Enzyme -1.48687 32.3 196
Bifunctional purine biosynthesis protein PURH ATIC Tchem Non-IDG -2.93014 835.0 246
Inosine triphosphate pyrophosphatase ITPA Tbio Enzyme -2.54659 339.8 215
Phosphoribosylformylglycinamidine synthase PFAS Tbio Enzyme -2.83741 653.1 88
Thiopurine S-methyltransferase TPMT Tchem Enzyme -2.23217 165.6 275
Adenosine kinase ADK Tchem Kinase -2.53745 340.0 298
Xanthine dehydrogenase/oxidase XDH Tclin Enzyme -2.69810 506.6 179
AMP deaminase 1 AMPD1 Tchem Enzyme -2.35602 227.5 148
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] NUDT2 Tbio Enzyme -1.25186 18.4 144
Adenylate kinase isoenzyme 1 AK1 Tbio Kinase -2.37718 230.1 422