Development Level

Tclin 27 | 613
Tbio 24 | 11,445
Tchem 8 | 1,598

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

embryonic lethality prior to t... 5 | 278
preweaning lethality, complete... 5 | 979
abnormal behavior 3 | 298
decreased total body fat amoun... 3 | 207
hyperactivity 3 | 148
abnormal embryo size 2 | 220
decreased fasted circulating g... 2 | 65
embryonic growth retardation 2 | 106
impaired glucose tolerance 2 | 75
increased bone mineral content 2 | 108
increased startle reflex 2 | 112
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal embryo development 1 | 7
abnormal epididymis morphology 1 | 42
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal limb bud morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal sensory capabilities-... 1 | 8
abnormal skin morphology 1 | 50
abnormal somite shape 1 | 5
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
bleb 1 | 2
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating iron lev... 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart 1 | 210
increased body length 1 | 32
increased circulating magnesiu... 1 | 10
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased vertical activity 1 | 24
limb grasping 1 | 41
long tibia 1 | 25
pale yolk sac 1 | 25
preweaning lethality, incomple... 1 | 499
small epididymis 1 | 3

Disease

Carcinoma 41 | 11,493
psoriasis 33 | 6,694
glioblastoma 29 | 5,792
atypical teratoid / rhabdoid tumor 26 | 5,112
ependymoma 26 | 4,679
medulloblastoma, large-cell 26 | 6,241
ovarian cancer 26 | 8,520
group 3 medulloblastoma 24 | 4,104
adult high grade glioma 23 | 3,801
Atrial Fibrillation 22 | 124
osteosarcoma 21 | 7,950
primitive neuroectodermal tumor 21 | 3,035
lung cancer 20 | 4,740
oligodendroglioma 20 | 2,850
Breast cancer 18 | 3,578
lung adenocarcinoma 18 | 2,716
lung carcinoma 18 | 2,843
Kidney cancer 16 | 2,613
astrocytic glioma 16 | 2,597
colon cancer 16 | 1,478
Heart disease 15 | 306
Congestive heart failure 14 | 113
Epilepsy 14 | 792
diabetes mellitus 14 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
invasive ductal carcinoma 14 | 2,951
non-small cell lung cancer 14 | 2,890
pancreatic cancer 14 | 2,398
subependymal giant cell astrocytoma 14 | 2,287
Astrocytoma, Pilocytic 13 | 3,081
Pick disease 13 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
malignant mesothelioma 13 | 3,232
Autosomal recessive predisposition 12 | 1,442
Cardiomyopathy 12 | 116
Hypertension 12 | 396
Chronic heart failure 11 | 46
Hypertensive disease 11 | 292
Long QT syndrome 11 | 39
ductal carcinoma in situ 11 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
pituitary cancer 11 | 1,972
Syncope 10 | 22
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Bipolar Disorder 9 | 666
Brugada syndrome 9 | 29
Cardiomyopathy, Dilated 9 | 83
Heart failure 9 | 162
acute quadriplegic myopathy 9 | 1,158
adrenocortical carcinoma 9 | 1,428
cystic fibrosis 9 | 1,696
fibroadenoma 9 | 559
interstitial cystitis 9 | 2,312
Depressive disorder 8 | 409
Familial atrial fibrillation 8 | 23
Hypertensive disorder 8 | 56
Poisoning by digitalis glycoside 8 | 8
Prolonged QT interval 8 | 15
Schizophrenia 8 | 1,160
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 7 | 21
Atrioventricular block 7 | 35
Cardiac Arrhythmia 7 | 103
Cardiac arrest 7 | 36
Coronary artery disease 7 | 268
Dilated cardiomyopathy 7 | 56
Duchenne muscular dystrophy 7 | 601
Familial isolated dilated cardiomyopathy 7 | 41
Heart conduction disease 7 | 83
Hypertrophic Cardiomyopathy 7 | 117
LEFT VENTRICULAR NONCOMPACTION 10 7 | 40
LEFT VENTRICULAR NONCOMPACTION 8 7 | 40
Liver cancer 7 | 604
Long philtrum 7 | 137
Parkinson's disease 7 | 392
Paroxysmal atrial fibrillation 7 | 14
Romano-Ward Syndrome 7 | 12
Seizures 7 | 596
Sudden Cardiac Death 7 | 29
Ventricular Fibrillation 7 | 17
breast carcinoma 7 | 1,638
tuberculosis 7 | 2,010
Atopic dermatitis 6 | 952
Broad flat nasal bridge 6 | 236
Cardiomegaly 6 | 116
Cerebrovascular disease 6 | 238
Congenital ear anomaly NOS (disorder) 6 | 29
Intellectual disability 6 | 1,016
Long QT syndrome 1 6 | 20
Myocardial Ischemia 6 | 169
Nasal bridge wide 6 | 236
Tachycardia, Ventricular 6 | 22
Timothy syndrome 6 | 11
Torsades de Pointes 6 | 8
group 4 medulloblastoma 6 | 1,855
Acquired scoliosis 5 | 281
Curvature of spine 5 | 282
Mental Depression 5 | 333
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
pancreatic carcinoma 5 | 562
ulcerative colitis 5 | 1,819

Tissue

Cardiovascular System 59 | 15,192
Digestive Tract 59 | 17,369
Endocrine System 59 | 18,159
Female tissues 58 | 17,400
Liver and Pancreas 58 | 16,750
Male tissues 58 | 17,142
Nervous System 58 | 16,725
Respiratory system 58 | 16,393
Blood and immune system 57 | 16,909
Skin and soft tissues 57 | 17,230
Urinary Tract 57 | 16,678

Target Family

Ion Channel 23 | 344
Non-IDG 15 | 12,091
Transporter 11 | 473
Enzyme 4 | 4,145
GPCR 4 | 408
Kinase 2 | 634

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Potassium voltage-gated channel subfamily D member 3 KCND3 Tclin Ion Channel -2.34610 217.9 162
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Tclin Ion Channel -2.48671 270.6 121
Alpha-1-syntrophin SNTA1 Tbio Non-IDG -1.49227 31.4 254
Beta-2-syntrophin SNTB2 Tbio Non-IDG -1.20042 14.7 121
Sodium/potassium-transporting ATPase subunit gamma FXYD2 Tclin Enzyme -1.58017 39.0 64
Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G Tclin Ion Channel -2.16668 140.8 217
Inward rectifier potassium channel 2 KCNJ2 Tchem Ion Channel -2.36978 224.8 221
Potassium voltage-gated channel subfamily H member 2 KCNH2 Tclin Ion Channel -3.22575 1653.9 243