Development Level

Tchem 18 | 1,598
Tbio 10 | 11,445
Tclin 8 | 613

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal gait 2 | 69
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased body weight 2 | 161
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal maxilla morphology 1 | 17
abnormal testis morphology 1 | 43
decreased circulating creatini... 1 | 39
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased circulating glucose ... 1 | 24
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 31 | 11,493
ovarian cancer 28 | 8,520
Cancer 25 | 2,499
lung cancer 25 | 4,740
osteosarcoma 22 | 7,950
glioblastoma 21 | 5,792
psoriasis 19 | 6,694
medulloblastoma, large-cell 17 | 6,241
Breast cancer 14 | 3,578
atypical teratoid / rhabdoid tumor 14 | 5,112
invasive ductal carcinoma 14 | 2,951
Kidney cancer 12 | 2,613
group 3 medulloblastoma 12 | 4,104
Schizophrenia 11 | 1,160
interstitial cystitis 11 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
pancreatic cancer 11 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
subependymal giant cell astrocytoma 10 | 2,287
Byzanthine arch palate 9 | 194
Downward slant of palpebral fissure 9 | 158
Hypoplastic mandible condyle 9 | 275
Mandibular hypoplasia 9 | 275
Micrognathism 9 | 275
Orbital separation excessive 9 | 244
Short stature 9 | 531
juvenile dermatomyositis 9 | 1,187
lung carcinoma 9 | 2,843
non-small cell lung cancer 9 | 2,890
Acquired scoliosis 8 | 281
Astrocytoma, Pilocytic 8 | 3,081
Blepharoptosis 8 | 231
Cognitive delay 8 | 608
Concave bridge of nose 8 | 195
Curvature of spine 8 | 282
Depressed nasal bridge 8 | 195
Depressed nasal root/bridge 8 | 195
Dull intelligence 8 | 645
Global developmental delay 8 | 608
Intellectual disability 8 | 1,016
Low intelligence 8 | 645
Lung Neoplasms 8 | 232
Melanoma 8 | 711
Mental Retardation 8 | 645
Mental and motor retardation 8 | 608
Mental deficiency 8 | 645
Multiple myeloma 8 | 1,332
Muscle hypotonia 8 | 571
Noonan syndrome 8 | 34
Pectus excavatum 8 | 100
Poor school performance 8 | 645
Stomach Neoplasms 8 | 300
adult high grade glioma 8 | 3,801
ependymoma 8 | 4,679
tuberculosis 8 | 2,010
Arthritis 7 | 290
Big calvaria 7 | 147
Breast Neoplasms 7 | 445
Congenital Epicanthus 7 | 177
Cryptorchidism 7 | 296
Delayed bone age 7 | 136
Epilepsy 7 | 792
Frontal bossing 7 | 157
Hemangioma, Cavernous 7 | 20
High forehead 7 | 102
Increased head circumference 7 | 147
Increased size of cranium 7 | 147
Increased size of skull 7 | 147
Mammary Neoplasms 7 | 425
Neck webbing 7 | 35
Pick disease 7 | 1,894
Strabismus 7 | 270
Tall forehead 7 | 102
Waldenstrons macroglobulinemia 7 | 765
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
diabetes mellitus 7 | 1,728
group 4 medulloblastoma 7 | 1,855
lung adenocarcinoma 7 | 2,716
malignant mesothelioma 7 | 3,232
oligodendroglioma 7 | 2,850
Alzheimer's disease 6 | 658
Asthma 6 | 385
Chubby cheeks 6 | 50
Feeding difficulties in infancy 6 | 175
Full cheeks 6 | 50
Hyperplasia of cheeks 6 | 50
Hypertrophy of cheeks 6 | 50
Low-set, posteriorly rotated ears 6 | 110
Myopia 6 | 176
Puffy cheeks 6 | 50
Seizures 6 | 596
Short neck 6 | 140
Triangular face 6 | 58
Vascular disease 6 | 319
breast carcinoma 6 | 1,638
cutaneous lupus erythematosus 6 | 1,057
ductal carcinoma in situ 6 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
ulcerative colitis 6 | 1,819

Tissue

Blood and immune system 35 | 16,909
Cardiovascular System 35 | 15,192
Digestive Tract 35 | 17,369
Endocrine System 35 | 18,159
Female tissues 35 | 17,400
Liver and Pancreas 35 | 16,750
Male tissues 35 | 17,142
Nervous System 35 | 16,725
Respiratory system 35 | 16,393
Skin and soft tissues 35 | 17,230
Urinary Tract 35 | 16,678

Target Family

Kinase 19 | 634
Non-IDG 10 | 12,091
Enzyme 7 | 4,145

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
Linker for activation of T-cells family member 1 LAT Tbio Non-IDG -2.16291 169.4 667
Immunoglobulin heavy constant epsilon IGHE Tclin Non-IDG 0.00000 0
GRB2-associated-binding protein 2 GAB2 Tbio Non-IDG -2.08460 139.8 494
Dual specificity mitogen-activated protein kinase kinase 4 MAP2K4 Tchem Kinase -2.43646 236.7 998
Dual specificity mitogen-activated protein kinase kinase 7 MAP2K7 Tchem Kinase -3.66356 3766.3 513
Cytosolic phospholipase A2 PLA2G4A Tchem Enzyme -2.68316 506.7 274