Development Level

Tbio 32 | 11,445
Tclin 28 | 613
Tchem 17 | 1,598
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to t... 6 | 278
hyperactivity 5 | 148
abnormal behavior 4 | 298
decreased total body fat amoun... 4 | 207
increased startle reflex 4 | 112
abnormal embryo size 2 | 220
decreased body weight 2 | 161
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
embryonic growth retardation 2 | 106
impaired glucose tolerance 2 | 75
increased bone mineral content 2 | 108
increased lean body mass 2 | 172
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal embryo development 1 | 7
abnormal epididymis morphology 1 | 42
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal limb bud morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal sensory capabilities-... 1 | 8
abnormal skin morphology 1 | 50
abnormal somite shape 1 | 5
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
bleb 1 | 2
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased pulmonary respirator... 1 | 5
decreased respiratory quotient 1 | 16
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged heart 1 | 210
increased IgA level 1 | 1
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating choleste... 1 | 66
increased circulating magnesiu... 1 | 10
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
long tibia 1 | 25
pale yolk sac 1 | 25
preweaning lethality, incomple... 1 | 499
small epididymis 1 | 3
thrombocytopenia 1 | 56

Disease

Carcinoma 53 | 11,493
psoriasis 42 | 6,694
glioblastoma 37 | 5,792
ovarian cancer 37 | 8,520
atypical teratoid / rhabdoid tumor 33 | 5,112
ependymoma 33 | 4,679
medulloblastoma, large-cell 33 | 6,241
group 3 medulloblastoma 29 | 4,104
osteosarcoma 28 | 7,950
adult high grade glioma 27 | 3,801
lung cancer 25 | 4,740
Atrial Fibrillation 24 | 124
Breast cancer 23 | 3,578
lung adenocarcinoma 23 | 2,716
primitive neuroectodermal tumor 23 | 3,035
oligodendroglioma 22 | 2,850
diabetes mellitus 21 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
pancreatic cancer 20 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
Epilepsy 19 | 792
invasive ductal carcinoma 19 | 2,951
lung carcinoma 19 | 2,843
Astrocytoma, Pilocytic 18 | 3,081
astrocytic glioma 18 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
non-small cell lung cancer 18 | 2,890
Kidney cancer 17 | 2,613
subependymal giant cell astrocytoma 17 | 2,287
Autosomal recessive predisposition 16 | 1,442
Heart disease 16 | 306
colon cancer 16 | 1,478
malignant mesothelioma 16 | 3,232
Cancer 14 | 2,499
Congestive heart failure 14 | 113
Hypertension 14 | 396
Pick disease 14 | 1,894
ductal carcinoma in situ 13 | 1,745
pituitary cancer 13 | 1,972
Cardiomyopathy 12 | 116
Schizophrenia 12 | 1,160
acute quadriplegic myopathy 12 | 1,158
Chronic heart failure 11 | 46
Hypertensive disease 11 | 292
Long QT syndrome 11 | 39
active Crohn's disease 11 | 922
interstitial cystitis 11 | 2,312
tuberculosis 11 | 2,010
Bipolar Disorder 10 | 666
Depressive disorder 10 | 409
Syncope 10 | 22
fibroadenoma 10 | 559
Brugada syndrome 9 | 29
Cardiomyopathy, Dilated 9 | 83
Coronary artery disease 9 | 268
Heart failure 9 | 162
Parkinson's disease 9 | 392
Prostatic Neoplasms 9 | 495
adrenocortical carcinoma 9 | 1,428
cystic fibrosis 9 | 1,696
Chemical and Drug Induced Liver Injury 8 | 195
Duchenne muscular dystrophy 8 | 601
Familial atrial fibrillation 8 | 23
Long philtrum 8 | 137
Poisoning by digitalis glycoside 8 | 8
Prolonged QT interval 8 | 15
astrocytoma 8 | 1,146
group 4 medulloblastoma 8 | 1,855
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 7 | 21
Atrioventricular block 7 | 35
Broad flat nasal bridge 7 | 236
Cardiac Arrhythmia 7 | 103
Cardiac arrest 7 | 36
Cardiomegaly 7 | 116
Dilated cardiomyopathy 7 | 56
Familial isolated dilated cardiomyopathy 7 | 41
Heart conduction disease 7 | 83
Hypertensive disorder 7 | 56
Hypertrophic Cardiomyopathy 7 | 117
LEFT VENTRICULAR NONCOMPACTION 10 7 | 40
LEFT VENTRICULAR NONCOMPACTION 8 7 | 40
Liver cancer 7 | 604
Liver disease 7 | 237
Mental Depression 7 | 333
Mood Disorders 7 | 184
Multiple myeloma 7 | 1,332
Nasal bridge wide 7 | 236
Obesity 7 | 678
Paroxysmal atrial fibrillation 7 | 14
Romano-Ward Syndrome 7 | 12
Seizures 7 | 596
Sudden Cardiac Death 7 | 29
Torsades de Pointes 7 | 8
Ventricular Fibrillation 7 | 17
breast carcinoma 7 | 1,638
ulcerative colitis 7 | 1,819
Myocardial Ischemia 6 | 169
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
juvenile dermatomyositis 6 | 1,187

Tissue

Digestive Tract 78 | 17,369
Liver and Pancreas 77 | 16,750
Male tissues 75 | 17,142
Skin and soft tissues 75 | 17,230
Endocrine System 74 | 18,159
Female tissues 74 | 17,400
Urinary Tract 74 | 16,678
Blood and immune system 73 | 16,909
Nervous System 73 | 16,725
Respiratory system 73 | 16,393
Cardiovascular System 72 | 15,192

Target Family

Ion Channel 23 | 344
Non-IDG 23 | 12,091
Enzyme 16 | 4,145
Transporter 11 | 473
GPCR 3 | 408
Kinase 2 | 634

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Potassium voltage-gated channel subfamily D member 3 KCND3 Tclin Ion Channel -2.34610 217.9 162
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Tclin Ion Channel -2.48671 270.6 121
Alpha-1-syntrophin SNTA1 Tbio Non-IDG -1.49227 31.4 254
Beta-2-syntrophin SNTB2 Tbio Non-IDG -1.20042 14.7 121
Sodium/potassium-transporting ATPase subunit gamma FXYD2 Tclin Enzyme -1.58017 39.0 64
Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G Tclin Ion Channel -2.16668 140.8 217
Inward rectifier potassium channel 2 KCNJ2 Tchem Ion Channel -2.36978 224.8 221
Potassium voltage-gated channel subfamily H member 2 KCNH2 Tclin Ion Channel -3.22575 1653.9 243