Development Level

Tbio 12 | 11,445
Tclin 5 | 613
Tchem 4 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
decreased hemoglobin content 1 | 68
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
embryonic lethality prior to t... 1 | 278
increased bone mineral content 1 | 108
increased fasted circulating g... 1 | 76

Disease

Carcinoma 17 | 11,493
ovarian cancer 13 | 8,520
psoriasis 12 | 6,694
glioblastoma 11 | 5,792
lung cancer 11 | 4,740
medulloblastoma, large-cell 11 | 6,241
osteosarcoma 11 | 7,950
Autosomal recessive predisposition 10 | 1,442
Epilepsy 10 | 792
atypical teratoid / rhabdoid tumor 9 | 5,112
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
adult high grade glioma 7 | 3,801
group 3 medulloblastoma 7 | 4,104
Cancer 6 | 2,499
Cognitive delay 6 | 608
Dull intelligence 6 | 645
Global developmental delay 6 | 608
Intellectual disability 6 | 1,016
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental and motor retardation 6 | 608
Mental deficiency 6 | 645
Muscle hypotonia 6 | 571
Poor school performance 6 | 645
Seizures 6 | 596
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
non-small cell lung cancer 6 | 2,890
primitive neuroectodermal tumor 6 | 3,035
Liver Cirrhosis, Experimental 5 | 769
Schizophrenia 5 | 1,160
ependymoma 5 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
lung carcinoma 5 | 2,843
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
Infantile onset 4 | 238
Kidney cancer 4 | 2,613
Succinic semialdehyde dehydrogenase deficiency 4 | 16
astrocytic glioma 4 | 2,597
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
gastric cancer 4 | 459
interstitial cystitis 4 | 2,312
nasopharyngeal carcinoma 4 | 1,058
pancreatic cancer 4 | 2,398
Anemia 3 | 365
Anemia, Hemolytic 3 | 55
Autistic Disorder 3 | 364
Breast cancer 3 | 3,578
Cardiovascular system disease 3 | 246
Cerebellar Ataxia 3 | 304
Chemical and Drug Induced Liver Injury 3 | 195
Contact Dermatitis 3 | 81
Dermatitis, Contact 3 | 71
Down syndrome 3 | 499
Hyperammonemia 3 | 30
Hypoglycemia 3 | 152
Multiple myeloma 3 | 1,332
Obesity 3 | 678
Pick disease 3 | 1,894
Toxic encephalopathy 3 | 141
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
hepatocellular carcinoma 3 | 547
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
Abnormality of metabolism/homeostasis 2 | 134
Astrocytoma, Pilocytic 2 | 3,081
Atherosclerosis 2 | 291
Cerebral palsy 2 | 40
Chronic Lymphocytic Leukemia 2 | 262
Citrullinemia 2 | 14
Dysarthria 2 | 192
Encephalitis 2 | 64
Epilepsy characterized by intractable complex partial seizures 2 | 28
Hyperreflexia 2 | 209
Hypertension 2 | 396
Kidney disease 2 | 430
Lethargy 2 | 77
Motor delay 2 | 147
Myocardial Infarction 2 | 151
Myocardial Ischemia 2 | 169
No development of motor milestones 2 | 147
Precancerous Conditions 2 | 80
Prostatic Neoplasms 2 | 495
Status Epilepticus 2 | 98
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
chronic rhinosinusitis 2 | 512
esophageal adenocarcinoma 2 | 737
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
nephrosclerosis 2 | 333
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010

Tissue

Blood and immune system 21 | 16,909
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678
Cardiovascular System 20 | 15,192

Target Family

Enzyme 19 | 4,145
Kinase 1 | 634
Non-IDG 1 | 12,091

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 21 | 21
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutaminase liver isoform, mitochondrial GLS2 Tbio Enzyme -3.14287 1343.1 167
Alanine aminotransferase 1 GPT Tbio Enzyme -2.47451 285.2 217
Aspartate aminotransferase, mitochondrial GOT2 Tbio Enzyme -3.23630 1435.0 450
Glutathione synthetase GSS Tbio Enzyme -2.78139 592.8 229
Glutathione reductase, mitochondrial GSR Tclin Enzyme -3.00773 863.8 276
GMP synthase [glutamine-hydrolyzing] GMPS Tbio Enzyme -2.48490 295.1 194
Succinate-semialdehyde dehydrogenase, mitochondrial ALDH5A1 Tclin Enzyme -2.23586 168.4 347
CAD protein CAD Tchem Non-IDG -2.23887 168.4 224
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 Tbio Enzyme -1.74725 52.8 197
Glutamate dehydrogenase 1, mitochondrial GLUD1 Tbio Enzyme -2.39787 257.7 148