Development Level

Tbio 24 | 11,445
Tchem 2 | 1,598
Tclin 2 | 613

IMPC Phenotype

decreased circulating alkaline... 2 | 46
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 22 | 11,493
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
Autosomal recessive predisposition 19 | 1,442
ovarian cancer 17 | 8,520
Seizures 15 | 596
Epilepsy 14 | 792
Cognitive delay 13 | 608
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
Muscle hypotonia 13 | 571
Hypoglycemia 12 | 152
glioblastoma 12 | 5,792
lung cancer 12 | 4,740
Lethargy 11 | 77
atypical teratoid / rhabdoid tumor 11 | 5,112
interstitial cystitis 11 | 2,312
osteosarcoma 11 | 7,950
psoriasis 11 | 6,694
medulloblastoma, large-cell 10 | 6,241
Maple syrup urine disease 9 | 24
Metabolic acidosis 9 | 90
Vomiting 9 | 116
adult high grade glioma 9 | 3,801
ependymoma 9 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
ulcerative colitis 9 | 1,819
Comatose 8 | 56
lung carcinoma 8 | 2,843
Acidosis, Lactic 7 | 97
Dull intelligence 7 | 645
Intellectual disability 7 | 1,016
Lactic acidemia 7 | 95
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
invasive ductal carcinoma 7 | 2,951
lung adenocarcinoma 7 | 2,716
Breast cancer 6 | 3,578
Dystonia 6 | 164
Dystonic disease 6 | 106
Feeding difficulties in infancy 6 | 175
Pick disease 6 | 1,894
beta-ketothiolase deficiency 6 | 13
colon cancer 6 | 1,478
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
3-Methylcrotonyl-CoA carboxylase deficiency 5 | 11
Astrocytoma, Pilocytic 5 | 3,081
Cerebellar Ataxia 5 | 304
Kidney cancer 5 | 2,613
Pancreatitis 5 | 123
Propionic acidemia 5 | 16
adrenocortical carcinoma 5 | 1,428
astrocytic glioma 5 | 2,597
cystic fibrosis 5 | 1,696
gastric carcinoma 5 | 807
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
tuberculosis 5 | 2,010
3-methylglutaconic aciduria 4 | 29
Brain Edema 4 | 50
Cerebral Edema 4 | 30
Dehydration 4 | 40
Failure to gain weight 4 | 365
Glycinuria 4 | 10
HYPERGLYCINURIA (disorder) 4 | 12
Hallucinations 4 | 34
Hallucinations, Sensory 4 | 33
Hepatomegaly 4 | 285
Infantile onset 4 | 238
Isovaleric acidemia 4 | 15
Liver Cirrhosis, Experimental 4 | 769
Medium chain acyl-CoA dehydrogenase deficiency 4 | 13
Methylmalonic acidemia 4 | 37
Multiple myeloma 4 | 1,332
Pediatric failure to thrive 4 | 365
Short chain acyl-CoA dehydrogenase deficiency 4 | 9
Waldenstrons macroglobulinemia 4 | 765
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
nephrosclerosis 4 | 333
Anemia 3 | 365
Carnitine deficiency 3 | 6
Delayed speech and language development 3 | 112
Hemoglobin low 3 | 124
Language Delay 3 | 112
Lipid metabolism disorder 3 | 114
Multiple acyl-CoA dehydrogenase deficiency 3 | 25
Speech Delay 3 | 112
Speech impairment 3 | 112
active Crohn's disease 3 | 922
aldosterone-producing adenoma 3 | 665
chronic lymphosyte leukemia 3 | 204
fibroadenoma 3 | 559
pituitary cancer 3 | 1,972

Tissue

Blood and immune system 28 | 16,909
Cardiovascular System 28 | 15,192
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Nervous System 28 | 16,725
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678

Target Family

Enzyme 28 | 4,145

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 28 | 28
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..