Development Level

Tbio 8 | 11,445
Tchem 7 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 2 | 298
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
cataract 1 | 92
decreased granulocyte number 1 | 6
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
female infertility 1 | 60
hypoactivity 1 | 132
increased lean body mass 1 | 172
increased startle reflex 1 | 112
male infertility 1 | 123
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 12 | 11,493
ovarian cancer 12 | 8,520
psoriasis 9 | 6,694
medulloblastoma, large-cell 7 | 6,241
osteosarcoma 7 | 7,950
Cancer 6 | 2,499
Homocystinuria 6 | 21
Hyperhomocysteinemia 6 | 37
Schizophrenia 5 | 1,160
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
Autosomal recessive predisposition 4 | 1,442
Kidney cancer 4 | 2,613
Lymphoma, Non-Hodgkin 4 | 24
adrenocortical carcinoma 4 | 1,428
atypical teratoid / rhabdoid tumor 4 | 5,112
dermatomyositis 4 | 966
group 3 medulloblastoma 4 | 4,104
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
spina bifida 4 | 1,074
tuberculosis 4 | 2,010
Astrocytoma, Pilocytic 3 | 3,081
Atherosclerosis 3 | 291
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Coronary artery disease 3 | 268
Dementia 3 | 175
Depressive disorder 3 | 409
Down syndrome 3 | 499
Hypermethioninemia 3 | 11
Hypertension 3 | 396
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Multiple myeloma 3 | 1,332
Prostatic Neoplasms 3 | 495
Sleeping sickness 3 | 37
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109
Adenocarcinoma of lung 2 | 142
Adverse reaction to drug 2 | 61
Alcoholic Intoxication, Chronic 2 | 289
Alzheimer's disease 2 | 658
Anemia 2 | 365
Atopic dermatitis 2 | 952
Brain Ischemia 2 | 110
Breast cancer 2 | 3,578
Cardiovascular Diseases 2 | 59
Cerebrovascular accident 2 | 63
Chronic Lymphocytic Leukemia 2 | 262
Cleft Lip 2 | 141
Cleft Palate 2 | 271
Colonic Neoplasms 2 | 142
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Disease Models, Animal 2 | 155
Drug-Related Side Effects and Adverse Reactions 2 | 62
Epilepsy 2 | 792
Glaucoma 2 | 239
Hearing Loss 2 | 17
MYELODYSPLASTIC SYNDROME 2 | 53
Malnutrition 2 | 11
Mood Disorders 2 | 184
Nervous System Diseases 2 | 53
Neural Tube Defects 2 | 31
Neurodegenerative disease 2 | 414
Neuropathy 2 | 261
Pick disease 2 | 1,894
Progressive disorder 2 | 142
Pulmonary embolism 2 | 55
Secondary progressive multiple sclerosis 2 | 10
Seizures 2 | 596
Steatohepatitis 2 | 44
Stomach Neoplasms 2 | 300
Venous Thrombosis 2 | 47
Waldenstrons macroglobulinemia 2 | 765
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
hearing impairment 2 | 199
juvenile dermatomyositis 2 | 1,187
lung cancer 2 | 4,740
medulloblastoma 2 | 720
nephrosclerosis 2 | 333
nervous system disorder 2 | 53
oligodendroglioma 2 | 2,850
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
ulcerative colitis 2 | 1,819

Tissue

Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Respiratory system 15 | 16,393

Target Family

Enzyme 16 | 4,145

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 16 | 16
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.21333 1562.7 1125
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
Methionine--tRNA ligase, cytoplasmic MARS Tchem Enzyme -1.75152 50.3 88
Serine hydroxymethyltransferase, cytosolic SHMT1 Tbio Enzyme -2.58690 370.4 181
Cystathionine gamma-lyase CTH Tchem Enzyme -2.70857 467.8 252
S-methyl-5'-thioadenosine phosphorylase MTAP Tchem Enzyme -2.24214 189.9 176
S-adenosylmethionine synthase isoform type-2 MAT2A Tbio Enzyme -1.91969 84.1 242
S-adenosylmethionine decarboxylase proenzyme AMD1 Tchem Enzyme -3.21826 1586.8 141
Methionine adenosyltransferase 2 subunit beta MAT2B Tbio Enzyme -1.09522 11.9 158
Spermidine synthase SRM Tchem Enzyme -1.65951 38.0 172