Development Level

Tbio 14 | 11,445
Tchem 5 | 1,598
Tclin 2 | 613

IMPC Phenotype

decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased lactate dehydrogenas... 1 | 16
decreased total body fat amoun... 1 | 207

Disease

Carcinoma 15 | 11,493
ovarian cancer 12 | 8,520
Autosomal recessive predisposition 10 | 1,442
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
glioblastoma 9 | 5,792
lung cancer 9 | 4,740
medulloblastoma, large-cell 9 | 6,241
osteosarcoma 9 | 7,950
Liver Cirrhosis, Experimental 8 | 769
ductal carcinoma in situ 8 | 1,745
psoriasis 8 | 6,694
Multiple myeloma 7 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
primitive neuroectodermal tumor 6 | 3,035
Acidosis, Lactic 5 | 97
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Lactic acidosis 5 | 51
Mental and motor retardation 5 | 608
Seizures 5 | 596
astrocytic glioma 5 | 2,597
breast carcinoma 5 | 1,638
diabetes mellitus 5 | 1,728
fibroadenoma 5 | 559
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
ulcerative colitis 5 | 1,819
Cancer 4 | 2,499
Epilepsy 4 | 792
Kidney cancer 4 | 2,613
Lactic acidemia 4 | 95
Leigh disease 4 | 100
Muscle hypotonia 4 | 571
Pick disease 4 | 1,894
Pyruvate decarboxylase deficiency 4 | 16
Schizophrenia 4 | 1,160
colon cancer 4 | 1,478
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
Astrocytoma, Pilocytic 3 | 3,081
Bipolar Disorder 3 | 666
Breast cancer 3 | 3,578
Carcinoma, Hepatocellular 3 | 228
Dull intelligence 3 | 645
Hypoglycemia 3 | 152
Increased serum lactate 3 | 60
Infantile onset 3 | 238
Intellectual disability 3 | 1,016
Kidney disease 3 | 430
Liver carcinoma 3 | 240
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Obesity 3 | 678
Poor school performance 3 | 645
Small head 3 | 374
adrenocortical carcinoma 3 | 1,428
ependymoma 3 | 4,679
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
pituitary cancer 3 | 1,972
Atopic dermatitis 2 | 952
Blepharoptosis 2 | 231
Cerebellar Ataxia 2 | 304
Cerebral atrophy 2 | 178
Complications of Diabetes Mellitus 2 | 5
Degenerative brain disorder 2 | 100
Diabetes Complications 2 | 6
Diabetes Mellitus, Experimental 2 | 108
Dystonia 2 | 164
Dystonic disease 2 | 106
Esophageal Squamous Cell Carcinoma 2 | 77
Fatty liver disease 2 | 103
Gaucher's disease 2 | 26
Heart failure 2 | 162
Highly variable severity 2 | 157
Hyper-beta-alaninemia 2 | 9
Hyperglycemia 2 | 137
Increased blood alanine 2 | 9
Increased serum alanine 2 | 9
Increased serum pyruvate 2 | 9
Lethargy 2 | 77
Mental Depression 2 | 333
Myocardial Ischemia 2 | 169
Prostatic Neoplasms 2 | 495
Respiratory Distress Syndrome, Adult 2 | 40
Squamous cell carcinoma of esophagus 2 | 77
Supratentorial atrophy 2 | 94
Variable expressivity 2 | 157
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
gastric carcinoma 2 | 807
nephrosclerosis 2 | 333
non primary Sjogren syndrome sicca 2 | 891
oligodendroglioma 2 | 2,850

Tissue

Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678
Blood and immune system 20 | 16,909
Female tissues 20 | 17,400
Cardiovascular System 19 | 15,192
Respiratory system 18 | 16,393

Target Family

Enzyme 18 | 4,145
Kinase 2 | 634
Non-IDG 1 | 12,091

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 21 | 21
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
L-lactate dehydrogenase A chain LDHA Tchem Enzyme -3.03454 1030.5 577
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.97865 1004.9 470
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] PCK1 Tbio Kinase -2.33937 203.6 442
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial PDHA1 Tbio Enzyme -2.31887 204.2 436
Acetyl-CoA carboxylase 1 ACACA Tchem Enzyme -3.14345 1376.6 426
Acetyl-CoA acetyltransferase, mitochondrial ACAT1 Tchem Enzyme -1.85518 70.4 397
Pyruvate kinase PKLR PKLR Tbio Kinase -2.37549 231.1 391
Aldose reductase AKR1B1 Tclin Enzyme -3.27314 1915.8 350
Lactoylglutathione lyase GLO1 Tchem Enzyme -2.54547 366.2 302
Malate dehydrogenase, cytoplasmic MDH1 Tbio Enzyme -2.64656 428.3 291