Development Level

Tchem 23 | 1,598
Tbio 15 | 11,445
Tclin 6 | 613
Tdark 3 | 6,588

IMPC Phenotype

decreased circulating insulin ... 2 | 76
increased circulating HDL chol... 2 | 80
preweaning lethality, complete... 2 | 979
abnormal epididymis morphology 1 | 42
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
decreased circulating HDL chol... 1 | 68
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
hydrometra 1 | 53
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 28 | 11,493
ovarian cancer 22 | 8,520
psoriasis 22 | 6,694
Cancer 21 | 2,499
osteosarcoma 20 | 7,950
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
lung cancer 17 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
glioblastoma 15 | 5,792
non-small cell lung cancer 14 | 2,890
atypical teratoid / rhabdoid tumor 13 | 5,112
medulloblastoma, large-cell 13 | 6,241
pancreatic cancer 13 | 2,398
Astrocytoma, Pilocytic 12 | 3,081
ependymoma 12 | 4,679
group 3 medulloblastoma 12 | 4,104
lung carcinoma 12 | 2,843
Hypertension 11 | 396
interstitial cystitis 11 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
invasive ductal carcinoma 11 | 2,951
lung adenocarcinoma 11 | 2,716
tuberculosis 11 | 2,010
ulcerative colitis 11 | 1,819
Prostatic Neoplasms 10 | 495
adult high grade glioma 10 | 3,801
astrocytoma 10 | 1,146
diabetes mellitus 10 | 1,728
Liver disease 9 | 237
Breast cancer 8 | 3,578
Chemical and Drug Induced Liver Injury 8 | 195
Schizophrenia 8 | 1,160
malignant mesothelioma 8 | 3,232
Asthma 7 | 385
active Crohn's disease 7 | 922
non primary Sjogren syndrome sicca 7 | 891
oligodendroglioma 7 | 2,850
Autosomal recessive predisposition 6 | 1,442
Cerebrovascular disease 6 | 238
Drug-Related Side Effects and Adverse Reactions 6 | 62
Kidney disease 6 | 430
Obesity 6 | 678
Rheumatoid arthritis 6 | 1,191
adrenocortical carcinoma 6 | 1,428
cutaneous lupus erythematosus 6 | 1,057
cystic fibrosis 6 | 1,696
primitive neuroectodermal tumor 6 | 3,035
subependymal giant cell astrocytoma 6 | 2,287
Acute kidney injury 5 | 70
Adverse reaction to drug 5 | 61
Atherosclerosis 5 | 291
Bipolar Disorder 5 | 666
Carcinoma, Hepatocellular 5 | 228
Cholestasis 5 | 155
Coronary artery disease 5 | 268
Epilepsy 5 | 792
Gout 5 | 106
Kidney Failure, Chronic 5 | 46
Liver Cirrhosis, Experimental 5 | 769
Liver carcinoma 5 | 240
Osteoarthritis 5 | 184
Toxic encephalopathy 5 | 141
ductal carcinoma in situ 5 | 1,745
esophageal adenocarcinoma 5 | 737
nephrosclerosis 5 | 333
Actinic keratosis 4 | 21
Alcoholic Intoxication, Chronic 4 | 289
Anemia 4 | 365
Arthritis 4 | 290
Atopic dermatitis 4 | 952
Bilirubin metabolic disorder 4 | 41
Breast Neoplasms 4 | 445
Depressive disorder 4 | 409
Diarrhea 4 | 253
Drug Hypersensitivity 4 | 34
Drug allergy 4 | 36
Dysmenorrhea 4 | 21
Fever 4 | 138
Hyperalgesia 4 | 83
Juvenile rheumatoid arthritis 4 | 111
Mammary Neoplasms 4 | 425
Melanoma 4 | 711
Menorrhagia 4 | 25
Mental Depression 4 | 333
Multiple myeloma 4 | 1,332
Myocardial Infarction 4 | 151
Pain 4 | 103
Pain agnosia 4 | 104
Patent ductus arteriosus 4 | 90
Reperfusion Injury 4 | 86
Sickle Cell Anemia 4 | 53
Urticaria 4 | 67
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
dermatomyositis 4 | 966
head and neck cancer 4 | 271
pancreatic carcinoma 4 | 562
Endometriosis 3 | 540
Vascular disease 3 | 319

Tissue

Digestive Tract 47 | 17,369
Urinary Tract 45 | 16,678
Liver and Pancreas 44 | 16,750
Male tissues 44 | 17,142
Skin and soft tissues 44 | 17,230
Female tissues 42 | 17,400
Endocrine System 40 | 18,159
Nervous System 40 | 16,725
Blood and immune system 39 | 16,909
Respiratory system 38 | 16,393
Cardiovascular System 34 | 15,192

Target Family

Enzyme 32 | 4,145
Non-IDG 13 | 12,091
Transporter 2 | 473

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UDP-glucuronosyltransferase 2B7 UGT2B7 Tchem Enzyme -2.31570 219.0 131
Cytochrome P450 4A11 CYP4A11 Tbio Non-IDG -1.97180 93.7 142
Cytochrome P450 2C19 CYP2C19 Tchem Non-IDG -3.22652 1740.4 154
Cytochrome P450 2C8 CYP2C8 Tchem Non-IDG -2.55207 348.9 159
Leukotriene C4 synthase LTC4S Tchem Enzyme -1.98032 93.9 89
Docosahexaenoic acid omega-hydroxylase CYP4F3 CYP4F3 Tbio Enzyme -1.70683 50.7 114
Prostacyclin synthase PTGIS Tchem Enzyme -2.55019 341.8 152
Cytochrome P450 4F8 CYP4F8 Tdark Non-IDG 0.00000 34
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.23035 1641.3 479
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731