Development Level

Tbio 10 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal brain morphology 1 | 13
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal neural tube morpholog... 1 | 12
abnormal skin morphology 1 | 50
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
female infertility 1 | 60
hydroencephaly 1 | 14
pale yolk sac 1 | 25
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 14 | 8,520
Carcinoma 8 | 11,493
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
osteosarcoma 8 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
glioblastoma 7 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
invasive ductal carcinoma 7 | 2,951
pancreatic cancer 7 | 2,398
cystic fibrosis 6 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung carcinoma 6 | 2,843
malignant mesothelioma 6 | 3,232
Astrocytoma, Pilocytic 5 | 3,081
ependymoma 5 | 4,679
interstitial cystitis 5 | 2,312
lung cancer 5 | 4,740
medulloblastoma, large-cell 5 | 6,241
pituitary cancer 5 | 1,972
psoriasis 5 | 6,694
ulcerative colitis 5 | 1,819
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
Pick disease 4 | 1,894
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
non-small cell lung cancer 4 | 2,890
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Cancer 3 | 2,499
Schizophrenia 3 | 1,160
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
ductal carcinoma in situ 3 | 1,745
lung adenocarcinoma 3 | 2,716
primary pancreatic ductal adenocarcinoma 3 | 1,109
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Dull intelligence 2 | 645
Failure to gain weight 2 | 365
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Motor delay 2 | 147
Myopia 2 | 176
No development of motor milestones 2 | 147
Obesity 2 | 678
Pediatric failure to thrive 2 | 365
Pellagra 2 | 26
Poor school performance 2 | 645
Rickets 2 | 49
acute quadriplegic myopathy 2 | 1,158
axial spondyloarthropathy 2 | 28
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
head and neck cancer 2 | 271
hereditary spastic paraplegia 2 | 318
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
urothelial carcinoma 2 | 318
Abnormal trabecular bone morphology 1 | 6
Abnormality of the cerebral vasculature 1 | 6
Achalasia 1 | 13
Adrenal rest tumor 1 | 5
Bilirubin metabolic disorder 1 | 41
Calcinosis 1 | 70
Carcinoma, squamous cell of head and neck 1 | 31
Congenital adrenal hyperplasia 1 | 73
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Exanthema 1 | 43
Exhibitionism 1 | 7
Familial glucocorticoid deficiency 1 | 4
Fatty liver disease 1 | 103
GLUCOCORTICOID DEFICIENCY 1 1 | 5
Gaucher disease type 3 1 | 67
Genu varum 1 | 29
Glucose Intolerance 1 | 19
Hyperkeratosis 1 | 50
Increased susceptibility to bacterial infections 1 | 42
Linear atrophy 1 | 15
Ovarian hyperstimulation syndrome 1 | 19
Prone to bacterial infection 1 | 42
Pseudoxanthoma elasticum 1 | 18
Quadriparesis 1 | 8
Rectal prolapse 1 | 19
Recurrent bacterial infection 1 | 42
Retinal Hemorrhage 1 | 6
Schistosomiasis 1 | 35
Sinusitis 1 | 65
triple-A syndrome 1 | 17

Tissue

Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678

Target Family

Enzyme 12 | 4,145
Kinase 2 | 634

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 14 | 14
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nicotinamide riboside kinase 1 NMRK1 Tbio Kinase -0.84939 6.66 143
NAD(P) transhydrogenase, mitochondrial NNT Tbio Enzyme -2.49624 309.2 112
Glutamine-dependent NAD(+) synthetase NADSYN1 Tbio Enzyme -1.21917 15.2 60
Nicotinamide N-methyltransferase NNMT Tchem Enzyme -2.09313 121.9 268
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 NMNAT2 Tbio Enzyme -1.54038 36.0 111
Cytosolic purine 5'-nucleotidase NT5C2 Tbio Enzyme -2.24348 166.8 144
Aldehyde oxidase AOX1 Tbio Enzyme -2.65775 418.6 161
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 ENPP1 Tchem Enzyme -2.74480 552.8 275
Purine nucleoside phosphorylase PNP Tclin Enzyme -2.75207 531.4 165
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667