Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal lens morphology 2 | 81
abnormal bone mineralization 1 | 38
abnormal heart morphology 1 | 162
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased mean corpuscular vol... 1 | 79
enlarged heart 1 | 210
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 7 | 11,493
ovarian cancer 7 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Peroxisomal disease 6 | 22
Adrenoleukodystrophy 5 | 29
Epilepsy 5 | 792
Muscle hypotonia 5 | 571
Seizures 5 | 596
psoriasis 5 | 6,694
Autosomal recessive predisposition 4 | 1,442
Cataract 4 | 297
Hepatomegaly 4 | 285
Lens Opacities 4 | 231
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
Abnormal skeletal development 3 | 60
Abnormality of metabolism/homeostasis 3 | 134
Abnormality of retinal pigmentation 3 | 111
Addison Disease 3 | 18
Adrenal cortical hypofunction 3 | 23
Atopic dermatitis 3 | 952
Blepharoptosis 3 | 231
Byzanthine arch palate 3 | 194
Cardiomyopathies 3 | 110
Carnitine palmitoyltransferase II deficiency 3 | 14
Cerebellar Ataxia 3 | 304
Chondrodysplasia punctata 3 | 41
Developmental regression 3 | 95
Difficulties with night vision 3 | 87
Elevated hepatic transaminases 3 | 81
Elevated levels of phytanic acid 3 | 15
Feeding difficulties in infancy 3 | 175
Hepatic enzyme increased 3 | 81
High forehead 3 | 102
Hydronephrosis 3 | 89
Infantile Refsum disease 3 | 23
Liver Dysfunction 3 | 99
Liver Failure 3 | 73
Liver enzymes abnormal 3 | 81
Liver function test increased 3 | 81
Liver function tests abnormal finding 3 | 81
Loss of developmental milestones 3 | 95
Low Vision 3 | 174
Mental deterioration in childhood 3 | 95
Multicystic Dysplastic Kidney 3 | 52
Muscle Weakness 3 | 170
Neurodevelopmental regression 3 | 95
Night Blindness 3 | 101
Nystagmus 3 | 317
Osteochondrodysplasias 3 | 72
Polymicrogyria 3 | 48
Psychomotor regression 3 | 95
Psychomotor regression beginning in infancy 3 | 95
Psychomotor regression in infants 3 | 95
Psychomotor regression, progressive 3 | 95
Refsum disease 3 | 20
Respiratory Insufficiency 3 | 132
Respiratory function loss 3 | 121
Retinal pigment epithelial abnormality 3 | 111
Retinitis Pigmentosa 3 | 226
Sensorineural Hearing Loss (disorder) 3 | 284
Small head 3 | 374
Subclinical abnormal liver function tests 3 | 81
Tall forehead 3 | 102
Transaminases increased 3 | 81
Visual Impairment 3 | 174
Zellweger syndrome 3 | 37
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
ulcerative colitis 3 | 1,819
Adrenoleukodystrophy, Neonatal 2 | 13
Clouding of corneal stroma 2 | 50
Decreased to absent deep tendon reflexes 2 | 42
Embryotoxon 2 | 28
Hypotonia, severe 2 | 33
Icterus 2 | 82
Impaired cognition 2 | 96
Infantile Refsum Disease (disorder) 2 | 13
Large bregma sutures 2 | 46
Large fontanelle 2 | 46
Large, late-closing fontanelle 2 | 46
Liver diseases 2 | 87
Long narrow head 2 | 75
Malformations of Cortical Development, Group II 2 | 31
Mental impairment 2 | 95
Muscle weakness, progressive 2 | 22
Penile hypospadias 2 | 106
Peroxisome biogenesis disorders 2 | 11
Posterior embryotoxon 2 | 28
Premature Birth 2 | 77
Premature birth of newborn 2 | 67
Pyloric Stenosis 2 | 47
Triangular face 2 | 58
Visual field constriction 2 | 36
Wide bregma sutures 2 | 46

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Enzyme 6 | 4,145
Transporter 3 | 473
Non-IDG 2 | 12,091

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 11 | 11
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial carnitine/acylcarnitine carrier protein SLC25A20 Tbio Transporter -2.28462 188.7 139
Long-chain-fatty-acid--CoA ligase 1 ACSL1 Tbio Enzyme -2.59850 388.5 222
Peroxisomal membrane protein PEX14 PEX14 Tbio Non-IDG -1.56143 37.1 205
Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 Tchem Enzyme -2.28515 186.9 359
2-hydroxyacyl-CoA lyase 1 HACL1 Tbio Enzyme -1.82472 63.8 159
Peroxisomal membrane protein PEX13 PEX13 Tbio Non-IDG -1.58768 38.1 68
Phytanoyl-CoA dioxygenase, peroxisomal PHYH Tbio Enzyme -2.34936 221.5 300
ATP-binding cassette sub-family D member 1 ABCD1 Tbio Transporter -2.06857 127.3 269
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.97865 1004.9 470
ATP-binding cassette sub-family D member 2 ABCD2 Tbio Transporter -1.65079 43.1 185