Development Level

Tbio 5 | 11,445
Tchem 4 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

abnormal behavior 2 | 298
preweaning lethality, complete... 2 | 979
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
cataract 1 | 92
decreased granulocyte number 1 | 6
decreased prepulse inhibition 1 | 82
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
increased startle reflex 1 | 112

Disease

Carcinoma 9 | 11,493
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
Autosomal recessive predisposition 4 | 1,442
Cancer 4 | 2,499
Hyperhomocysteinemia 4 | 37
Hypermethioninemia 4 | 11
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
Atherosclerosis 3 | 291
Homocystinuria 3 | 21
Hypertension 3 | 396
Multiple myeloma 3 | 1,332
Waldenstrons macroglobulinemia 3 | 765
diabetes mellitus 3 | 1,728
medulloblastoma, large-cell 3 | 6,241
Down syndrome 2 | 499
Dull intelligence 2 | 645
Failure to gain weight 2 | 365
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Myocardial Infarction 2 | 151
Neurodegenerative disease 2 | 414
Pancreatitis 2 | 123
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Poor school performance 2 | 645
Steatohepatitis 2 | 44
Substance abuse 2 | 59
astrocytic glioma 2 | 2,597
dermatomyositis 2 | 966
lung adenocarcinoma 2 | 2,716
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
progressive supranuclear palsy 2 | 676
psoriasis 2 | 6,694
Abnormal urinary amino-acid findings 1 | 38
Agoraphobia 1 | 21
Alcohol dependence 1 | 107
Alcoholism 1 | 45
Amblyopia 1 | 38
Aminoaciduria 1 | 38
Aphasia 1 | 26
Apraxia 1 | 26
Arachnodactyly 1 | 49
Argininosuccinic aciduria 1 | 17
Atypical depressive disorder 1 | 6
Bilirubin metabolic disorder 1 | 41
Bulimia nervosa 1 | 14
COPD 1 | 118
Cerebral Ischemia 1 | 37
Charcot-Marie-Tooth disease 1 | 62
Cholangitis 1 | 32
Clubbing 1 | 9
Congenital arteriovenous malformation 1 | 8
Coughing 1 | 25
Cystathioninuria 1 | 2
Dental abnormalities 1 | 60
Dyspnea 1 | 76
Ectopia Lentis 1 | 17
Embolism and Thrombosis 1 | 6
Fatty liver disease 1 | 103
Generalized anxiety disorder 1 | 29
Hepatic methionine adenosyltransferase deficiency 1 | 7
Hepatolenticular Degeneration 1 | 24
Hyperkyphosis 1 | 111
Inadequate arch length for tooth size 1 | 45
Joint stiffness 1 | 84
Knee joint valgus deformity 1 | 56
Kyphoscoliosis deformity of spine 1 | 60
Kyphosis deformity of spine 1 | 114
Long QT syndrome 1 | 39
Lung Diseases, Interstitial 1 | 5
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mitral Valve Prolapse Syndrome 1 | 39
Osteochondritis dissecans 1 | 17
Panic disorder 1 | 61
Patellofemoral pain syndrome 1 | 10
Pityriasis versicolor 1 | 19
Pulmonary alveolar proteinosis 1 | 15
Retinal Neovascularization 1 | 4
Sleeping sickness 1 | 37
Sparse scalp hair 1 | 42
Tall stature 1 | 34
Thromboembolism 1 | 15
Tinea manuum 1 | 4
Tooth Abnormalities 1 | 69
Tooth Crowding 1 | 45
Tooth mass arch size discrepancy 1 | 45
Tooth size discrepancy 1 | 45
Vaccinia 1 | 36
Vaginal discharge 1 | 9
Voyeurism 1 | 4
interstitial lung disease 1 | 298
non-inflammatory breast cancer 1 | 66

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Enzyme 11 | 4,145

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 11 | 11
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Selenide, water dikinase 2 SEPHS2 Tdark Enzyme -1.42671 25.3 0
Selenocysteine lyase SCLY Tbio Enzyme -2.50435 312.5 90
Cystathionine beta-synthase CBS Tchem Enzyme -3.25635 3246.1 391
Methionine--tRNA ligase, cytoplasmic MARS Tchem Enzyme -1.75152 50.3 88
S-adenosylmethionine synthase isoform type-2 MAT2A Tbio Enzyme -1.91969 84.1 242
Methionine adenosyltransferase 2 subunit beta MAT2B Tbio Enzyme -1.09522 11.9 158
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 PAPSS1 Tbio Enzyme -2.41857 281.0 125
Adenosylhomocysteinase AHCY Tchem Enzyme -2.69517 493.7 257
Glutathione hydrolase 1 proenzyme GGT1 Tbio Enzyme -3.13033 1793.6 313
Methyltransferase-like protein 6 METTL6 Tdark Enzyme -0.27300 1.63 103